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Journal Articles

Integrating Computational Cytomorphological Analysis of Bone Marrow Smears and Clinical Data for Predicting Response to Venetoclax and Hypomethylating Agents in AML

Henri Sundquist, Mikael Tatun, Mikko Purhonen, Laura Toivanen, Johanna Rimpiläinen, Samuli Rounioja, Timo Siitonen, Marja Pyörälä, Pentti Mäntymaa, Sari Kytölä, Kimmo Porkka, Sanna Siitonen, Heikki Kuusanmäki, Mika Kontro, Oscar E. Brück
Journal: Blood
Blood (2024) 144 (Supplement 1): 4320.
https://doi.org/10.1182/blood-2024-206949
Published: 2024
Journal Articles

Integrative Analysis of Transcriptomic and Proteomic Data Identifies Patterns of Primary Resistance to Venetoclax-Azacitidine and Reveals Targetable Vulnerabilities in Acute Myeloid Leukemia (AML)

Ida Vänttinen, Joseph Saad, Tanja Ruokoranta, Sari Kytölä, Pia-Sofia Ettala, Marja Pyörälä, Johanna Rimpiläinen, Timo Siitonen, Caroline A. Heckman, Heikki Kuusanmäki, Mika Kontro
Journal: Blood
Blood (2024) 144 (Supplement 1): 2757.
https://doi.org/10.1182/blood-2024-209429
Published: 2024
Journal Articles

Ex Vivo Venetoclax Sensitivity Predicts Clinical Response in Acute Myeloid Leukemia in the Prospective VenEx Trial

Clinical Trials & Observations
Sari Kytölä, Ida Maria Vänttinen, Tanja Ruokoranta, Anu Partanen, Annasofia Holopainen, Joseph Saad, Milla E.L. Kuusisto, Sirpa Koskela, Riikka Katariina Räty, Maija Itälä-Remes, Imre Västrik, Minna Suvela, Alun Owen Parsons, Kimmo Porkka, Krister Wennerberg, Caroline A. Heckman, Tero Jalkanen, Teppo Huttunen, Pia Ettala, MD, Johanna Rimpiläinen, Timo Siitonen, Marja Pyörälä, Heikki Kuusanmäki, Mika Kontro
Journal: Blood
Blood blood.2024024968.
https://doi.org/10.1182/blood.2024024968
Published: 2024
Includes: Supplemental data
Journal Articles

Targeting Venetoclax Resistance in TP53 -Mutated Acute Myeloid Leukemia

Ida Vänttinen, Tanja Ruokoranta, Joseph J Saad, Sari Kytölä, Monica Hellesøy, Stein-Erik Gullaksen, Pia-Sofia Ettala, Marja Pyörälä, Johanna Rimpiläinen, Timo Siitonen, Krister Wennerberg, Bjorn T. Gjertsen, Caroline A. Heckman, Mika Kontro, Heikki Kuusanmäki
Journal: Blood
Blood (2023) 142 (Supplement 1): 2927.
https://doi.org/10.1182/blood-2023-189340
Published: 2023
Journal Articles

Ex Vivo Venetoclax Sensitivity Testing Predicts Response and Overall Survival in De Novo and s/R/R AML Patients Treated with Azacitidine and Venetoclax

Sari Kytölä, Ida Vänttinen, Tanja Ruokoranta, Annasofia Holopainen, Anu Partanen, Milla E.L. Kuusisto, Sirpa Koskela, Riikka Räty, Maija Itälä-Remes, Amanda Ranta, Minna Suvela, Alun Parsons, Imre Västrik, Sanna M. Siitonen, Kimmo Porkka, Krister Wennerberg, Caroline A. Heckman, Pia Ettala, Johanna Rimpiläinen, Timo Siitonen, Marja Pyörälä, Heikki Kuusanmäki, Mika Kontro
Journal: Blood
Blood (2022) 140 (Supplement 1): 2020–2022.
https://doi.org/10.1182/blood-2022-159391
Published: 2022
Journal Articles

Ex Vivo Drug Sensitivity Testing to Predict Response to Venetoclax + Azacitidine in Acute Myeloid Leukemia: Interim Results of the Prospective Multicenter Phase II Venex Trial

Heikki Kuusanmäki, Sari Kytölä, Ida Vänttinen, Amanda Ranta, Tanja Ruokoranta, Annasofia Holopainen, Sirpa Koskela, Milla E.L. Kuusisto, Kimmo Porkka, Riikka Räty, Imre Västrik, Krister Wennerberg, Caroline A. Heckman, Pia Ettala, Marja Pyörälä, Johanna Rimpiläinen, Timo Siitonen, Mika Kontro
Journal: Blood
Blood (2021) 138 (Supplement 1): 228.
https://doi.org/10.1182/blood-2021-147691
Published: 2021
Journal Articles

Aspariginase-Triggered Hyperglycerimedia: An Analysis on Germline Regulatory Gene Variations in Adult Acute Lymphoblastic Leukemia Patients

Sari Kytölä, MD, Suvi Rantamo, MSc, Matti Jauhiainen, PhD, Kimmo Porkka, MD PhD, Outi Kilpivaara, PhD, Ulla Wartiovaara-Kautto, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1287.
https://doi.org/10.1182/blood.V130.Suppl_1.1287.1287
Published: 2017