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Sara Salerno
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Journal Articles

Mutations At The FLT3 Activation Loop D835 Residue Confer Differential Resistance To Clinically Active FLT3 Inhibitors

Kimberly Lin, BS, Catherine C Smith, MD, Sara Salerno, PharmD, Neil P. Shah, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3929.
https://doi.org/10.1182/blood.V122.21.3929.3929
Published: 2013
Journal Articles

Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD

Catherine C. Smith, Elisabeth A. Lasater, Xiaotian Zhu, Kimberly C. Lin, Whitney K. Stewart, Lauren E. Damon, Sara Salerno, Neil P. Shah
Journal: Blood
Blood (2013) 121 (16): 3165–3171.
https://doi.org/10.1182/blood-2012-07-442871
Published: 2013
Includes: Supplemental data
Journal Articles

Constitutively Activating Mutations At the FLT3 Activation Loop Residue D835 Are Associated with Clinical Resistance to AC220

Catherine C Smith, MD, Jason Chin, PhD, Elisabeth Lasater, PhD, Amy L. Paguirigan, PhD, Kimberly Lin, BS, Whitney Stewart, BS, Sara Salerno, BS, Lauren E Damon, Mark J. Levis, MD, PhD, Alexander E Perl, MD, Kevin Travers, PhD, Andrew Kasarskis, PhD, Jerald P. Radich, MD, Neil Shah, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 674.
https://doi.org/10.1182/blood.V120.21.674.674
Published: 2012
Journal Articles

Activity of Allosteric, Switch-Pocket, ABL/FLT3 Kinase Inhibitor DCC2036 Against Cultured and Primary AML Progenitors with FLT-ITD or FLT3 Kinase Domain Mutations

Warren Fiskus, BSc, PhD, Catherine C. Smith, MD, Jacqueline Smith, MS, Scott C. Wise, MS, Elisabeth Lasater, PhD, Lauren E. Damon, Sara Salerno, BS, Allan Fleming, MD, Ruben Reyes, MD, Siddhartha Ganguly, MD, Mark S. Berger, MD, Tom J. Rutkoski, Ph.D, Joseph McGuirk, DO, Neil Shah, MD, PhD, Kapil N. Bhalla, MD
Journal: Blood
Blood (2011) 118 (21): 2611.
https://doi.org/10.1182/blood.V118.21.2611.2611
Published: 2011
Journal Articles

Single Molecule Real Time (SMRT™) Sequencing Sensitively Detects Polyclonal and Compound BCR-ABL in Patients Who Relapse on Kinase Inhibitor Therapy,

Catherine C. Smith, MD, Michael Brown, PhD, Jason Chin, PhD, Corynn Kasap, BS, Sara Salerno, BS, Lauren E. Damon, Kevin Travers, PhD, Susana Wang, Andrew Kasarskis, PhD, Eric Schadt, PhD, Neil Shah, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3752.
https://doi.org/10.1182/blood.V118.21.3752.3752
Published: 2011
Journal Articles

Analysis of in Vitro Activity of the Clinically-Active ABL/FLT3 Inhibitor Ponatinib (AP24534) Against AC220-Resistant FLT3-ITD Mutants

Catherine C. Smith, MD, Lauren E. Damon, Xiaotian Zhu, PhD, Sara Salerno, BS, Neil Shah, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 930.
https://doi.org/10.1182/blood.V118.21.930.930
Published: 2011
Journal Articles

Validation of FLT3-ITD As a Therapeutic Target in Human Acute Myeloid Leukemia

Catherine C. Smith, MD, Jason Chin, PhD, Qi Wang, PhD, Sara Salerno, BS, Lauren E. Damon, Jeremy P. Hunt, Mark J. Levis, MD, PhD, Alexander E Perl, MD, Kevin Travers, PhD, Susana Wang, Andrew Kasarskis, PhD, Eric Schadt, PhD, John Kuriyan, PhD, Neil Shah, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 937.
https://doi.org/10.1182/blood.V118.21.937.937
Published: 2011