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Journal Articles

De Novo UBE2A Mutations Are Recurrently Acquired during CML Progression and Interfere with Myeloid Differentiation Pathways

VERA Magistroni, PhD, Rocco Piazza, MD PhD, Mario Mauri, PhD, Caterina Mezzatesta, M.Sc., Nitesh Sharma, PhD, Wendy Parker, PhD, Andreas Schreiber, PhD, David T Yeung, PhDBSc,FRACP,FRCPA,MBBS, Sara Redaelli, PhD, Paul Wang, Alessandra Pirola, M.Sc., Luca Massimino, PhD, Praveen Khandelwal, Stefania Citterio, Michela Viltadi, Jacqueline Boultwood, PhD, Alessandro Morotti, MD PhD, Giuseppe Saglio, MD PhD, Dong-Wook Kim, MD PhD, Susan Branford, PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 44.
https://doi.org/10.1182/blood.V130.Suppl_1.44.44
Published: 2017
Journal Articles

Identification of SETBP1 As an Epigenetic Hub Protein That Induces the Transcription of a Network of Development-Related Genes

Rocco Piazza, MD PhD, VERA Magistroni, PhD, Sara Redaelli, PhD, Mario Mauri, PhD, Luca Massimino, PhD, Alessandro Sessa, PhD, Marco Peronaci, PhD, Maciej Lalowski, PhD, Rabah Soliymani, PhD, Caterina Mezzatesta, M.Sc., Alessandra Pirola, M.Sc., Federica Banfi, M.Sc., Alicia Rubio, PhD, Delphine Rea, MD, Fabio Stagno, MD PhD, Emilio Usala, MD, Bruno Martino, Leonardo Campiotti, MD, Michele Merli, Francesco Passamonti, MD, Francesco Onida, MD, Alessandro Morotti, MD PhD, Francesca Pavesi, MD, Marco Bregni, MD, Vania Broccoli, PhD, Marc Baumann, MBA, MB, PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4980.
https://doi.org/10.1182/blood.V130.Suppl_1.4980.4980
Published: 2017
Journal Articles

ETNK1 Is an Early Event and SETBP1 a Late Event in Atypical Chronic Myeloid Leukemia

Antonio Niro, Rocco Piazza, MDPhD, Gabriele Merati, Alessandra Pirola, MSc, Carla Donadoni, MSc, PhD, Diletta Fontana, MSc, Sara Redaelli, PhD, Caterina Mezzatesta, Rossella Renso, MD, Francesca Farina, MD, Delphine Rea, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2015) 126 (23): 3652.
https://doi.org/10.1182/blood.V126.23.3652.3652
Published: 2015
Journal Articles

Synergistic Activity of ALK and mTOR Inhibitors for the Treatment of NPM-ALK Positive Lymphoma

Sara Redaelli, PhD, Monica Ceccon, PhD, Alessandra Pirola, MSc, Marco Peronaci, MSc, Carlo Gambacorti-Passerini, MD, Luca Mologni, PhD
Journal: Blood
Blood (2015) 126 (23): 3710.
https://doi.org/10.1182/blood.V126.23.3710.3710
Published: 2015
Journal Articles

Recurrent ETNK1 mutations in atypical chronic myeloid leukemia

Carlo B. Gambacorti-Passerini, Carla Donadoni, Andrea Parmiani, Alessandra Pirola, Sara Redaelli, Giovanni Signore, Vincenzo Piazza, Luca Malcovati, Diletta Fontana, Roberta Spinelli, Vera Magistroni, Giuseppe Gaipa, Marco Peronaci, Alessandro Morotti, Cristina Panuzzo, Giuseppe Saglio, Emilio Usala, Dong-Wook Kim, Delphine Rea, Konstantinos Zervakis, Nora Viniou, Argiris Symeonidis, Heiko Becker, Jacqueline Boultwood, Leonardo Campiotti, Matteo Carrabba, Elena Elli, Graham R. Bignell, Elli Papaemmanuil, Peter J. Campbell, Mario Cazzola, Rocco Piazza
Journal: Blood
Blood (2015) 125 (3): 499–503.
https://doi.org/10.1182/blood-2014-06-579466
Published: 2015
Includes: Supplemental data
Journal Articles

Recurrent KIT D816V Mutation in Atypical Chronic Myeloid Leukemia

Sara Redaelli, PhD, Rocco Piazza, MD PhD, Alessandra Pirola, M.Sc., Vera Magistroni, PhD, Susanne Schnittger, PhD, Manja Meggendorfer, PhD, Nicholas C.P. Cross, PhD, Delphine Rea, MD PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2014) 124 (21): 3576.
https://doi.org/10.1182/blood.V124.21.3576.3576
Published: 2014
Journal Articles

Evidence of ETNK1 Somatic Variants in Atypical Chronic Myeloid Leukemia

Carla Donadoni, PhD, Rocco Piazza, MD PhD, Diletta Fontana, M.Sc., Andrea Parmiani, M.Sc., Alessandra Pirola, M.Sc., Sara Redaelli, PhD, Giovanni Signore, M.Sc., Vincenzo Piazza, PhD, Luca Malcovati, MD, Roberta Spinelli, M.Sc., Vera Magistroni, PhD, Giuseppe Gaipa, Marco Peronaci, M.Sc., Alessandro Morotti, MDPhD, Cristina Panuzzo, PhD, Giuseppe Saglio, MD, Elena Maria Elli, MD, Emilio Usala, MD, Dong-Wook Kim, MD PhD, Delphine Rea, MDPhD, Konstantinos Zervakis, MD, Nora-Athina Viniou, MD, Argiris Symeonidis, MD, Heiko Becker, MD, Jacqueline Boultwood, PhD, Leonardo Campiotti, MD, Matteo G Carrabba, MD, Graham R Bignell, PhD, Elli Papaemmanuil, PhD, Peter J Campbell, PhD, Mario Cazzola, MD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2014) 124 (21): 2212.
https://doi.org/10.1182/blood.V124.21.2212.2212
Published: 2014
Journal Articles

SETBP1 and CSF3R Mutations In Atypical Chronic Myeloid Leukemia

Rocco Piazza, MD, PhD, Sara Redaelli, PhD, Simona Valletta, Alessandra Pirola, M.Sc., Roberta Spinelli, M.Sc., Vera Magistroni, PhD, Dong-Wook Kim, MD, PhD, Nicholas C.P. Cross, PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2013) 122 (21): 2598.
https://doi.org/10.1182/blood.V122.21.2598.2598
Published: 2013
Journal Articles

High Response Rates To Crizotinib In Advanced, Chemoresistant ALK+ Lymphoma Patients

Sara Redaelli, PhD, Francesca Farina, MD, Alessandra Stasia, MD, Monica Ceccon, PhD, Luca Mologni, PhD, Cristina Messa, MD, Luca Guerra, MD, Giovanni Giudici, MS, Elena Sala, MS, Lara Mussolin, PhD, Dries Deeren, MD, Michael H. King, MD, Michael Steurer, MD, Rainer Ordemann, MD, Amos Cohen, MD, Matthias Grube, MD, Lea Bernard, MD, Gianpaolo Chiriano, PhD, Rocco Piazza, MD, PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2013) 122 (21): 368.
https://doi.org/10.1182/blood.V122.21.368.368
Published: 2013
Journal Articles

Recurrent SETBP1 Mutations in Atypical Chronic Myeloid Leukemia Abrogate an Ubiquitination Site and Dysregulate SETBP1 Protein Levels

Carlo Gambacorti-Passerini, MD, Simona Valletta, Nils Winkelmann, MD, Sara Redaelli, PhD, Roberta Spinelli, M.Sc., Alessandra Pirola, M.Sc., Laura Antolini, Luca Mologni, PhD, Carla Donadoni, Elli Papaemmanuil, PhD, Susanne Schnittger, PhD, Kim Dong-Wook, Jacqueline Boultwood, MD, Fabio Rossi, Giuseppe Gaipa, PhD, Greta De Martini, MD, Paola Francia di Celle, PhD, Hyun G. Jang, Valeria Fantin, PhD, Graham R Bignell, Vera Magistroni, PhD, Torsten Haferlach, MD, Enrico Maria Pogliani, MD, Peter Campbell, MD Phd, Andrew J Chase, PhD, William J Tapper, PhD, Nicholas C.P. Cross, PhD, FRCPath, Rocco Piazza, MD, PhD
Journal: Blood
Blood (2012) 120 (21): LBA-2.
https://doi.org/10.1182/blood.V120.21.LBA-2.LBA-2
Published: 2012
Journal Articles

A New BCR-ABL1 Mutation (L248R) Is Highly Resistant to Imatinib, Bosutinib, Nilotinib and Dasatinib, but Can Be Inhibited by AP-24534 and DCC-2036.

Sara Redaelli, PhD, Luca Mologni, PhD, Roberta Rostagno, MS, Rocco Piazza, MD, PhD, Michela Viltadi, MS, Scott Wise, MS, Daniel Flynn, PhD, Carlo Gambacorti-Passerini, MD
Journal: Blood
Blood (2010) 116 (21): 3398.
https://doi.org/10.1182/blood.V116.21.3398.3398
Published: 2010
Journal Articles

Deregulated Activity and Localization of Glycogen Synthase Kinase 3β In Chronic Myeloid Leukemia Progenitors: Role In Leukemia Maintenance and Targeted Therapy.

Addolorata ML Coluccia, PhD, Simone De Leo, Emanuela de Luca, BSc, Giovanni Reddiconto, MD, Ilaria Palamà, BSc, Sara Redaelli, PhD, Serena De Matteis, Carlo Gambacorti-Passerini, MD, Luciana Dini, Prof, Michele Maffia, Prof
Journal: Blood
Blood (2010) 116 (21): 1216.
https://doi.org/10.1182/blood.V116.21.1216.1216
Published: 2010
Journal Articles

Bosutinib is a Substrate of the ABC Efflux Transporter P-Glycoprotein.

Pietro Perini, MS, Sara Redaelli, PhD, Rocco Piazza, MD, Michela Viltadi, MS, Frank Boschelli, PhD, Carlo Gambacorti, MD
Journal: Blood
Blood (2009) 114 (22): 3763.
https://doi.org/10.1182/blood.V114.22.3763.3763
Published: 2009
Journal Articles

BCR and BCR/ABL Regulation during Myeloid Differentiation in Healthy Donors and in Chronic Phase/Blast Crisis CML Patients

Manuela Marega, MS, Rocco Piazza, MD, Iris Meneghetti, Sara Redaelli, MS, Angela Mogavero, Carlo Gambacorti, MD
Journal: Blood
Blood (2008) 112 (11): 3204.
https://doi.org/10.1182/blood.V112.11.3204.3204
Published: 2008
Journal Articles

Determination of the Activity Profile of Bosutinib, Dasatinib and Nilotinib against 18 Imatinib Resistant Bcr/Abl Mutants

Sara Redaelli, MS, Rocco Piazza, MD, Roberta Rostagno, Marianna Sassone, MD, Vera Magistroni, PhD, Pietro Perini, MS, Manuela Marega, MS, Frank Boschelli, PhD, Carlo Gambacorti, MD
Journal: Blood
Blood (2008) 112 (11): 3220.
https://doi.org/10.1182/blood.V112.11.3220.3220
Published: 2008
Journal Articles

Synergistic Activity of the Novel Src/Abl Inhibitor Bosutinib in Combination with Imatinib.

Sara Redaelli, Frank Boschelli, Michela Viltadi, Iris Meneghetti, Carlo Gambacorti
Journal: Blood
Blood (2007) 110 (11): 2930.
https://doi.org/10.1182/blood.V110.11.2930.2930
Published: 2007
Journal Articles

NPM/ALK binds and phosphorylates the RNA/DNA-binding protein PSF in anaplastic large-cell lymphoma

Annamaria Galietta, Rosalind H. Gunby, Sara Redaelli, Paola Stano, Cristiana Carniti, Angela Bachi, Philip W. Tucker, Carmen J. Tartari, Ching-Jung Huang, Emanuela Colombo, Karen Pulford, Miriam Puttini, Rocco G. Piazza, Holger Ruchatz, Antonello Villa, Arianna Donella-Deana, Oriano Marin, Danilo Perrotti, Carlo Gambacorti-Passerini
Journal: Blood
Blood (2007) 110 (7): 2600–2609.
https://doi.org/10.1182/blood-2006-01-028647
Published: 2007
Includes: Supplemental data
Journal Articles

In Vitro and In Vivo Activity of SKI-606, a Novel Abl/Src Inhibitor, Against Imatinib Resistant BCR-ABL+ Neoplastic Cells.

Miriam Puttini, Addolorata M.L. Coluccia, Frank Boschelli, Anna Franceschino, Lucia Tornaghi, Shaheen Ahmed, Sara Redaelli, Rocco Piazza, Vera Magistroni, Federica Andreoni, Leonardo Scapozza, Franca Formelli, Carlo Gambacorti
Journal: Blood
Blood (2006) 108 (11): 2176.
https://doi.org/10.1182/blood.V108.11.2176.2176
Published: 2006