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Sandra Verploegen
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Journal Articles

Duohexabody-CD37, a Novel Bispecific Antibody with a Hexamerization-Enhancing Mutation Targeting CD37, Demonstrates Superior Complement-Dependent Cytotoxicity in Preclinical B-Cell Malignancy Models

Simone C. Oostindie, MSc, Hilma J. Van Der Horst, MSc, Marije B. Overdijk, PhD, Kristin Strumane, PhD, Sandra Verploegen, PhD, Margaret A. Lindorfer, PhD, Erica M. Cook, B.A., Martine E.D. Chamuleau, MD, Tuna Mutis, PhD, Janine Schuurman, PhD, A. Kate Sasser, PhD, Ronald P. Taylor, PhD, Paul W. H. I. Parren, PhD, Frank J. Beurskens, PhD, Esther C. W. Breij, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4170.
https://doi.org/10.1182/blood-2018-99-114723
Published: 2018
Journal Articles

Duobody-CD3xCD20 Shows Unique and Potent Preclinical Anti-Tumor Activity in Vitro and In Vivo , and Is Being Evaluated Clinically in Patients with B-Cell Malignancies

Ida H. Hiemstra, PhD, Patrick J. Engelberts, BS, Bart de Jong, BS, Danita H Schuurhuis, PhD, Theodora W. Salcedo, PhD DABT, Sandra Verploegen, PhD, Marten van der Zee, PhD, Arnout F. Gerritsen, PhD, Nedjad Losic, PhD, Sjeng Horbach, PhD, Roberto Oliveri, MD PhD, Jeroen J. Lammerts van Bueren, PhD, Pernille Autzen Usher, PhD, Janine Schuurman, PhD, Paul W. H. I. Parren, PhD, Esther C. W. Breij, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1664.
https://doi.org/10.1182/blood-2018-99-115957
Published: 2018
Journal Articles

Enhanced IgG Hexamerization Mediates Efficient C1q Docking and Complement-Dependent Cytotoxicity; Preclinical Proof Of Concept On Primary CLL and Burkitt Lymphoma

Frank J Beurskens, PhD, Rob N de Jong, PhD, Sandra Verploegen, PhD, Marleen Voorhorst, Kristin Strumane, PhD, Margaret A. Lindorfer, PhD, Ronald P. Taylor, PhD, Erica Ollmann Saphire, PhD, Dennis Burton, PhD, Janine Schuurman, PhD, Paul W.H.I. Parren, PhD
Journal: Blood
Blood (2013) 122 (21): 375.
https://doi.org/10.1182/blood.V122.21.375.375
Published: 2013
Journal Articles

Phagocytosis Is A Mechanism of Action for Daratumumab

Marije B. Overdijk, PhD student, Sandra Verploegen, PhD, Bögels Marijn, PhD student, Marjolein van Egmond, Prof., Richard W.J. Groen, PhD, Anton C.M. Martens, PhD, Jeroen Lammerts van Bueren, PhD, Wim Bleeker, PhD, Paul W.H.I. Parren, PhD
Journal: Blood
Blood (2012) 120 (21): 4054.
https://doi.org/10.1182/blood.V120.21.4054.4054
Published: 2012
Journal Articles

Protein kinase B (c-akt) regulates hematopoietic lineage choice decisions during myelopoiesis

Miranda Buitenhuis, Liesbeth P. Verhagen, Hanneke W. M. van Deutekom, Anders Castor, Sandra Verploegen, Leo Koenderman, Sten-Eirik W. Jacobsen, Paul J. Coffer
Journal: Blood
Blood (2008) 111 (1): 112–121.
https://doi.org/10.1182/blood-2006-07-037572
Published: 2008
Includes: Supplemental data
Journal Articles

Characterization of the role of CaMKI-like kinase (CKLiK) in human granulocyte function

Sandra Verploegen, Laurien Ulfman, Hanneke W. M. van Deutekom, Corneli van Aalst, Henk Honing, Jan-Willem J. Lammers, Leo Koenderman, Paul J. Coffer
Journal: Blood
Blood (2005) 106 (3): 1076–1083.
https://doi.org/10.1182/blood-2004-09-3755
Published: 2005
Journal Articles

Identification and characterization of CKLiK, a novel granulocyte Ca ++ /calmodulin-dependent kinase

Sandra Verploegen, Jan-Willem J. Lammers, Leo Koenderman, Paul J. Coffer
Journal: Blood
Blood (2000) 96 (9): 3215–3223.
https://doi.org/10.1182/blood.V96.9.3215
Published: 2000