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Saïd M. Sebti
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Journal Articles

Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells

Kuichun Zhu, Elvira Gerbino, Darrin M. Beaupre, Paul A. Mackley, Carlos Muro-Cacho, Craig Beam, Andrew D. Hamilton, Mathias G. Lichtenheld, William G. Kerr, William Dalton, Melissa Alsina, Saïd M. Sebti
Journal: Blood
Blood (2005) 105 (12): 4759–4766.
https://doi.org/10.1182/blood-2004-11-4307
Published: 2005
Journal Articles

Farnesyltransferase inhibitor tipifarnib is well tolerated, induces stabilization of disease, and inhibits farnesylation and oncogenic/tumor survival pathways in patients with advanced multiple myeloma

Clinical Trials & Observations
Melissa Alsina, Rafael Fonseca, Edward F. Wilson, A. Nelida Belle, Elvira Gerbino, Tammy Price-Troska, Rose M. Overton, Gregory Ahmann, Laura M. Bruzek, Alex A. Adjei, Scott H. Kaufmann, John J. Wright, Daniel Sullivan, Benjamin Djulbegovic, Alan B. Cantor, Philip R. Greipp, William S. Dalton, Saïd M. Sebti
Journal: Blood
Blood (2004) 103 (9): 3271–3277.
https://doi.org/10.1182/blood-2003-08-2764
Published: 2004
Journal Articles

Farnesyltransferase inhibitor R115777 in myelodysplastic syndrome: clinical and biologic activities in the phase 1 setting

Razelle Kurzrock, Hagop M. Kantarjian, Jorge E. Cortes, Neil Singhania, Deborah A. Thomas, Edward F. Wilson, John J. Wright, Emil J. Freireich, Moshe Talpaz, Saïd M. Sebti
Journal: Blood
Blood (2003) 102 (13): 4527–4534.
https://doi.org/10.1182/blood-2002-11-3359
Published: 2003