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Journal Articles

The Selective Anti Leukemic Effect of BL-8040, a Peptidic CXCR4 Antagonist, Is Mediated By Induction of Leukemic Blast Mobilization, Differentiation and Apoptosis: Results of Correlative Studies from a Ph2a Trial in Acute Myeloid Leukemia

Blood (2016) 128 (22): 2745.

https://doi.org/10.1182/blood.V128.22.2745.2745

Published: 2016

Journal Articles

Role of Mesenchymal Stem Cell Galectin 3 in the AML Tumor Microenvironment

Peter Ruvolo, PhD, Yihua Qiu, MD, Vivian Ruvolo, MS, Rui-Yu Wang, MD PhD, Zhihong Zeng, MD, Jared Burks, PhD, Rongqing Pan, MS, Numsen Hail, Jr., PhD, Teresa McQueen, Suk-Young Yoo, Steven M. Kornblau, MD, Michael Andreeff, MD PhD

Blood (2015) 126 (23): 1198.

https://doi.org/10.1182/blood.V126.23.1198.1198

Published: 2015

Journal Articles

Acute Myelogenous Leukemia (AML) Mesenchymal Stromal Cell (MSC) Have Distinct Protein Expression Patterns Compared to Normal MSC

Steven M. Kornblau, MD, Peter Ruvolo, PhD, Rui-Yu Wang, MD PhD, Vivian Ruvolo, MS, Yihua Qiu, MD, Venkata Lokesh Battula, PhD, Zhihong Zeng, MD, Teresa McQueen, Suk-Young Yoo, Marina Konopleva, MD PhD, Michael Andreeff, MD, PhD

Blood (2015) 126 (23): 3813.

https://doi.org/10.1182/blood.V126.23.3813.3813

Published: 2015

Journal Articles

Reverse Phase Protein Analysis of Mesenchymal Stem Cells from AML Patients and Healthy Donors Reveals Distinct Patterns of Protein Expression Reflecting Differences in Senescence, Differentiation and Survival Signaling

Peter P. Ruvolo, PhD, Venkata Lokesh Battula, PhD, YiHua Qui, MD, Vivian R Ruvolo, MA, Rodrigo Jacamo, PhD, Zhihong Zeng, MD, Rui-Yu Wang, MD PhD, Teresa McQueen, BS, Arvind Rao, SukYoung Yoo, Phuong M Le, Numsen Hail, PhD, Bing Z Carter, PhD, Steven M. Kornblau, MD, Michael Andreeff, MD PhD

Blood (2014) 124 (21): 4376.

https://doi.org/10.1182/blood.V124.21.4376.4376

Published: 2014

Journal Articles

Acute Myeloid Leukemia Cells Acquire Chemo-Resistance By Inducing Osteoblast Differentiation in Mesenchymal Stem Cells through up-Regulation of RUNX2

Venkata Lokesh Battula, PhD, Phuong M Le, Jeffrey Sun, BS, Teresa McQueen, BS, Anitha Somanchi, MS, Rui-Yu Wang, MD PhD, Dirk Strunk, MD, Elizabeth J Shpall, MD, Peter P. Ruvolo, PhD, Hagop M. Kantarjian, MD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD

Blood (2014) 124 (21): 2929.

https://doi.org/10.1182/blood.V124.21.2929.2929

Published: 2014

Journal Articles

MLN0128, a Second-Generation mTOR Kinase Inhibitor, Disrupts Survival Signaling and Triggers Apoptosis in AML

Zhihong Zeng, MD, Rui-Yu Wang, MD PhD, Yuexi Shi, MD, Yihua Qiu, MD, Duncan H Mak, MS, Kevin Coombes, PhD, Suk Young Yoo, PhD, Katti Jessen, Yi Liu, PhD, Christian Rommel, PhD, Hagop M. Kantarjian, MD, Steven M. Kornblau, MD, David Fruman, PhD, Michael Andreeff, MD PhD, Marina Konopleva, MD PhD

Blood (2014) 124 (21): 3613.

https://doi.org/10.1182/blood.V124.21.3613.3613

Published: 2014

Journal Articles

Phosphorylation Of GSK3β Is Associated With Inferior Survival In Acute Myeloid Leukemia and Is An Indicator Of AKT Activation In AML Blasts and Bone Marrow Mesenchymal Stem Cells

Peter P. Ruvolo, PhD, Rui-yu Wang, MD, PhD, Vivian R Ruvolo, MA, Rodrigo Jacamo, PhD, Teresa McQueen, BS, Gautam Borthakur, MD, Yihua Qiu, MD, Kevin R. Coombes, PhD, Nianxiang Zhang, Elizabeth J Shpall, MD, Richard E Champlin, MD, Ramiro Garzon, MD, Guido Marcucci, MD, Carlo M. Croce, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD, Steven M. Kornblau, MD

Blood (2013) 122 (21): 2551.

https://doi.org/10.1182/blood.V122.21.2551.2551

Published: 2013

Journal Articles

Proteomic, Gene Expression, and Micro-RNA Analysis Of Bone Marrow Mesenchymal Stromal Cells In Acute Myeloid Leukemia Identifies Pro-Inflammatory, Pro-Survival Signatures In Vitro and In Vivo

Blood (2013) 122 (21): 3685.

https://doi.org/10.1182/blood.V122.21.3685.3685

Published: 2013

Journal Articles

Mobilization and Elimination of FLT3-ITD+ Acute Myelogenous Leukemia (AML) Stem/Progenitor Cells by Plerixafor/G-CSF/Sorafenib: Results From a Phase I Trial in Relapsed/Refractory AML Patients

Michael Andreeff, MD, PhD, Zhihong Zeng, PhD, Mary A Kelly, RN, Rui-yu Wang, MD, PhD, Teresa McQueen, BS, Seshagiri Duvvuri, Gul Nowshad, Gautam Borthakur, MD, Jan A. Burger, MD, PhD, Tapan M. Kadia, M.D., Elias Jabbour, MD, Jorge E. Cortes, MD, Hagop M. Kantarjian, MD, Marina Konopleva, MD, PhD

Blood (2012) 120 (21): 142.

https://doi.org/10.1182/blood.V120.21.142.142

Published: 2012

Journal Articles

Leukemia Cell Mobilization with Plerixafor Plus G-CSF with Busulfan/Fludarabine and Allogeneic Hematopoietic Cell Transplantation in Patients with AML/MDS Is Associated with Decreased Complete Chimerism and GvHD, and Increased Risk of Relapse

Blood (2012) 120 (21): 360.

https://doi.org/10.1182/blood.V120.21.360.360

Published: 2012

Journal Articles

Proteomic Profiling of AML Bone Marrow-Derived Mesenchymal Stem Cells (MSC) Reveals Marked Differences From Normal MSC.

Rui-yu Wang, MD, PhD, Yi Hua Qiu, MD, Suk Young Yoo, PhD, Teresa McQueen, BS, Ye Chen, PhD, Zhihong Zeng, MD, Kevin R. Coombes, PhD, Wendy D. Schober, MLT (ASCP), Marina Konopleva, MD, PhD, Steven M. Kornblau, MD, PhD, Michael Andreeff, MD, PhD

Blood (2012) 120 (21): 2355.

https://doi.org/10.1182/blood.V120.21.2355.2355

Published: 2012

Journal Articles

p53 Activation of Mesenchymal Stromal Cells (MSC) Partially Abrogates Microenvironment-Mediated Resistance to FLT3 Inhibition In FLT3/ITD AML

Kensuke Kojima, MD, PhD, Teresa McQueen, Elizabeth J. Shpall, MD, Rui-Yu Wang, MD, PhD, Michael Andreeff, MD, PhD

Blood (2010) 116 (21): 2151.

https://doi.org/10.1182/blood.V116.21.2151.2151

Published: 2010

Journal Articles

A Phase I/II Trial of Plerixafor/G-CSF Combined with IV Bu/Flu Conditioning Regimen In AML/MDS Patients Undergoing Allogenic Stem Cell Transplantation

Blood (2010) 116 (21): 2358.

https://doi.org/10.1182/blood.V116.21.2358.2358

Published: 2010

Journal Articles

Mesenchymal Stem Cells From Patients with Acute Myeloid Leukemia (AML) Can Differentiate Into B-Cells in NOD/SCID/IL-2Rγ -/- Mice .

Rui-Yu Wang, MD, PhD, Yue-Xi Shi, Zhihong Zeng, MD, Wendy D. Schober, Teresa J. McQueen, BS, Vicki L. Hopwood, MS, BS, Borys Korchin, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD

Blood (2009) 114 (22): 4573.

https://doi.org/10.1182/blood.V114.22.4573.4573

Published: 2009

Journal Articles

Targeting IL3 Receptor in Chronic Myeloid Leukemia.

Olga Frolova, MD, PhD, Rui-Yu Wang, MD, PhD, Borys Korchin, Julie C. Watt, Jorge Cortes, MD, Arthur E. Frankel, MD, Hagop M. Kantarjian, MD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD

Blood (2009) 114 (22): 2172.

https://doi.org/10.1182/blood.V114.22.2172.2172

Published: 2009

Journal Articles

Clinical Evaluation of a Custom Genome Wide 44K Oligoarray for Copy Number Changes in Acute Myeloid Leukemia

Ankita Patel, Ph.D., Rui-Yu Wang, MD, PhD, Patricia Hixson, Ph.D., Jian Li, Aleksandar Milosavljevic, Ph.D., Hagop M Kantarjian, Sau w Cheung, Ph.D., Michael Andreeff, MD, PhD

Blood (2008) 112 (11): 4869.

https://doi.org/10.1182/blood.V112.11.4869.4869

Published: 2008

Journal Articles

Clonal Abnormalities in MSC Derived from AML Bone Marrows

Michael Andreeff, MD, PhD, Teresa McQueen, BS, Christopher Williams, Jun Gu, MS, MD, Vicki L. Hopwood, MS, BS, Taylor Appleberry, Corinn Rich, Stephanie Dallaire, PhD, MD, Steven Kornblau, MD, Rui-Yu Wang, MD, PhD

Blood (2008) 112 (11): 2428.

https://doi.org/10.1182/blood.V112.11.2428.2428

Published: 2008

Journal Articles

Apoptosis Inducing Factor Acts as a Survival Factor in Acute Myelogenous Leukemia through Mitochondrial Complex 1.

Rui-yu Wang, MD, PhD, Ismael J. Samudio, PhD, Teresa McQueen, BS, Wendy D. Schober, MLT, Vivian R. Ruvolo, Steven Kornblau, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD

Blood (2007) 110 (11): 1812.

https://doi.org/10.1182/blood.V110.11.1812.1812

Published: 2007

Journal Articles

Overexpression of Apoptosis-Inducing Factor (AIF) and Pro-Survival Function in AML.

Rui-Yu Wang, MD, PhD, Vivian R. Ruvolo, Teresa McQueen, Wendy D. Schober, Steven Kornblau, MD, Marina Konopleva, M.D., Ph.D., Michael Andreeff, M.D., PhD.

Blood (2006) 108 (11): 4395.

https://doi.org/10.1182/blood.V108.11.4395.4395

Published: 2006

Journal Articles

Mechanisms of Apoptosis Induction by BH3 Inhibitor ABT-737 in AML.

Michael Andreeff, MD, PhD, Rooha Contractor, Peter P. Ruvolo, PhD, Xingming Deng, MD, PhD, Ismael Samudio, PhD, Yue-Xi Shi, Teresa McQueen, BS, Rui-Yu Wang, MD, PhD, Wendy Schober, Xiaoyang Ling, PhD, Frank C. Marini, PhD, David Harris, Zeev Estrov, MD, James McCubrey, PhD, W. Stratford May, MD, PhD, Marina Konopleva, MD, PhD

Blood (2005) 106 (11): 244.

https://doi.org/10.1182/blood.V106.11.244.244

Published: 2005

NARROW

The Selective Anti Leukemic Effect of BL-8040, a Peptidic CXCR4 Antagonist, Is Mediated By Induction of Leukemic Blast Mobilization, Differentiation and Apoptosis: Results of Correlative Studies from a Ph2a Trial in Acute Myeloid Leukemia

Role of Mesenchymal Stem Cell Galectin 3 in the AML Tumor Microenvironment

Acute Myelogenous Leukemia (AML) Mesenchymal Stromal Cell (MSC) Have Distinct Protein Expression Patterns Compared to Normal MSC

Reverse Phase Protein Analysis of Mesenchymal Stem Cells from AML Patients and Healthy Donors Reveals Distinct Patterns of Protein Expression Reflecting Differences in Senescence, Differentiation and Survival Signaling

Acute Myeloid Leukemia Cells Acquire Chemo-Resistance By Inducing Osteoblast Differentiation in Mesenchymal Stem Cells through up-Regulation of RUNX2

MLN0128, a Second-Generation mTOR Kinase Inhibitor, Disrupts Survival Signaling and Triggers Apoptosis in AML

Phosphorylation Of GSK3β Is Associated With Inferior Survival In Acute Myeloid Leukemia and Is An Indicator Of AKT Activation In AML Blasts and Bone Marrow Mesenchymal Stem Cells

Proteomic, Gene Expression, and Micro-RNA Analysis Of Bone Marrow Mesenchymal Stromal Cells In Acute Myeloid Leukemia Identifies Pro-Inflammatory, Pro-Survival Signatures In Vitro and In Vivo

Mobilization and Elimination of FLT3-ITD+ Acute Myelogenous Leukemia (AML) Stem/Progenitor Cells by Plerixafor/G-CSF/Sorafenib: Results From a Phase I Trial in Relapsed/Refractory AML Patients

Leukemia Cell Mobilization with Plerixafor Plus G-CSF with Busulfan/Fludarabine and Allogeneic Hematopoietic Cell Transplantation in Patients with AML/MDS Is Associated with Decreased Complete Chimerism and GvHD, and Increased Risk of Relapse

Proteomic Profiling of AML Bone Marrow-Derived Mesenchymal Stem Cells (MSC) Reveals Marked Differences From Normal MSC.

p53 Activation of Mesenchymal Stromal Cells (MSC) Partially Abrogates Microenvironment-Mediated Resistance to FLT3 Inhibition In FLT3/ITD AML

A Phase I/II Trial of Plerixafor/G-CSF Combined with IV Bu/Flu Conditioning Regimen In AML/MDS Patients Undergoing Allogenic Stem Cell Transplantation

Mesenchymal Stem Cells From Patients with Acute Myeloid Leukemia (AML) Can Differentiate Into B-Cells in NOD/SCID/IL-2Rγ -/- Mice .

Targeting IL3 Receptor in Chronic Myeloid Leukemia.

Clinical Evaluation of a Custom Genome Wide 44K Oligoarray for Copy Number Changes in Acute Myeloid Leukemia

Clonal Abnormalities in MSC Derived from AML Bone Marrows

Apoptosis Inducing Factor Acts as a Survival Factor in Acute Myelogenous Leukemia through Mitochondrial Complex 1.

Overexpression of Apoptosis-Inducing Factor (AIF) and Pro-Survival Function in AML.

Mechanisms of Apoptosis Induction by BH3 Inhibitor ABT-737 in AML.

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American Society of Hematology

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American Society of Hematology

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