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Rui Chen, PhD
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Journal Articles

High-Density Domain-Focused CRISPR Screens Reveal Epigenetic Regulators of Hox/Meis Gene Expression in Acute Myeloid Leukemia

Karina Barbosa, BSc, Anagha Deshpande, PhD, Ping Xiang, PhD, Bo-Rui Chen, PhD, Adam Brown, MSc, Neil Robertson, Younguk Sun, PhD, John Doench, PhD, Peter D Adams, PhD, R. Keith Humphries, MD PhD, Prashant Mali, PhD, Aniruddha J. Deshpande, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-141412
Published: 2020
Journal Articles

Single Cell Profiling of DNMT3A-Mutant Progenitors Reveals LY86 As a Novel Pre-Leukemia Marker and Potential Therapeutic Target

Mira Jeong, PhD, Sangbae Kim, PhD, Yumei Li, PhD, Rui Chen, PhD, Premal Lulla, MBBS, Margaret Goodell, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2724.
https://doi.org/10.1182/blood-2019-123597
Published: 2019
Journal Articles

Genomic and Proteomic Profiling of AF10-Fusion Oncoproteins Reveal Mechanisms of Leukemogenesis and Actionable Targets

Bo-Rui Chen, PhD, Anagha Deshpande, PhD, Maria Kleppe, PhD, Narayana Yeddula, PhD, Sunnie Yoh, PhD, Scott A. Armstrong, MD PhD, Ross L. Levine, MD, Sumit Chanda, PhD, Aniruddha J. Deshpande, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 544.
https://doi.org/10.1182/blood-2018-99-119210
Published: 2018
Journal Articles

Association Between Down-Regulation of EZH2 and Abnormal Karyotype, Response to Hypomethylation Treatment, and Patient Survival in Myelodysplastic Syndromes

Yue Wei, Monica Cabrero, MD, Yu Jia, Hong Zheng, Hui Yang, MD, PhD, Zhihong Fang, Zach Bohannan, Rui Chen, PhD, Hui Wang, PhD, Simona Colla, Xia Wang, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2014) 124 (21): 3241.
https://doi.org/10.1182/blood.V124.21.3241.3241
Published: 2014
Journal Articles

Transcriptomic Evaluation of CD34+ Marrow Cells from Myelodysplastic Syndrome (MDS) Patients

Hogune Im, PhD, Varsha Rao, PhD, Kunju Joshi Sridhar, PhD, Rui Chen, PhD, George Mias, PhD, Yan Zhang, MD, Li Xiao, MD, Michael P Snyder, PhD, Peter L. Greenberg, MD
Journal: Blood
Blood (2014) 124 (21): 1894.
https://doi.org/10.1182/blood.V124.21.1894.1894
Published: 2014
Journal Articles

Phase I Study of Decitabine and Rapamycin in Relapsed/Refractory Acute Myelogenous Leukemia

Jane L. Liesveld, MD, Kristen O'Dwyer, MD, Michael W. Becker, MD, Deborah Mulford, MD, Alison Walker, MD, Rui Chen, PhD, Jeremy Bechelli, MS, Karen Rosell, BS, Craig T. Jordan, PhD, Mohammad Minhajuddin, PhD, Gordon L. Phillips, II, MD
Journal: Blood
Blood (2012) 120 (21): 3549.
https://doi.org/10.1182/blood.V120.21.3549.3549
Published: 2012
Journal Articles

Genome-Wide Chip-Seq Analysis of Histone Methylation Reveals Modulators of NF-κB Signaling and the Histone Demethylase JMJD3 as Implicated in Disease Progression in Myelodysplastic Syndrome (MDS).

Yue Wei, PhD, Rui Chen, PhD, Carlos E. Bueso-Ramos, MD, Hui Wang, PhD, Xingzhi Song, PhD, Jing Wang, Hui Yao, Martin Nguyen, Michael Fernandez, Hui Yang, MD, PhD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2009) 114 (22): 291.
https://doi.org/10.1182/blood.V114.22.291.291
Published: 2009