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Ronald Stam, PhD
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Journal Articles

Irinotecan Induces Complete Remission in MLL -Rearranged Acute Lymphoblastic Leukemia Xenografts

Patricia Garrido Castro, PhD, Mark Kerstjens, MSc, Sandra S Pinhanços, MSc, Pauline Schneider, BSc, Priscilla Wander, MSc, Rob Pieters, MD PhD, Ronald Stam, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3877.
https://doi.org/10.1182/blood.V130.Suppl_1.3877.3877
Published: 2017
Journal Articles

The Histone Deacetylase Inhibitor Panobinostat (LBH-589) Exerts Anti-Leukaemic Activity in a MLL-Rearranged ALL Xenograft Mouse Model

Patricia Garrido Castro, PhD, Eddy HJ Van Roon, PhD, Sandra S Mimoso Pinhancos, MSc, Pauline Schneider, BSc, Mark JB Kerstjens, MSc, Merel Willekes, BSc, Rob Pieters, MD PhD, Ronald Stam, PhD
Journal: Blood
Blood (2014) 124 (21): 3709.
https://doi.org/10.1182/blood.V124.21.3709.3709
Published: 2014
Journal Articles

Unravelling the Mirnome of MLL -Rearranged Acute Lymphoblastic Leukemia

Patricia Garrido Castro, PhD, Clara Bueno, PhD, Eddy HJ van Roon, PhD, Sandra S Mimoso Pinhancos, MSc, Pauline Schneider, BSc, Merel Willekes, BSc, Pablo Menendez, PhD, Rob Pieters, MD PhD, Ronald Stam, PhD
Journal: Blood
Blood (2014) 124 (21): 878.
https://doi.org/10.1182/blood.V124.21.878.878
Published: 2014
Journal Articles

Exome Sequencing Identifies Pxdn and DSP As Recurrently Mutated Genes in Infant ALL Patients Carrying a MLL-AF4 Translocation

Eddy HJ van Roon, PhD, Ronald Stam, PhD, Merel Willekes, BSc, Roland P. Kuiper, PhD, Rutger W.W. Brouwer, PhD, van IJcken F. Wilfred, PhD, Rob Pieters, MD PhD
Journal: Blood
Blood (2014) 124 (21): 130.
https://doi.org/10.1182/blood.V124.21.130.130
Published: 2014
Journal Articles

MEK Inhibition Is a Promising Therapeutic Strategy for MLL -Rearranged Infant ALL Patients Carrying RAS Mutations

Mark JB Kerstjens, MSc, Emma MC Driessen, MD, Merel Willekes, BSc, Sandra S Mimoso Pinhancos, MSc, Rob Pieters, MD PhD, Ronald Stam, PhD
Journal: Blood
Blood (2014) 124 (21): 919.
https://doi.org/10.1182/blood.V124.21.919.919
Published: 2014
Journal Articles

MLL Fusion Driven Activation of CDK6 Potentiates Proliferation in MLL- rearranged Infant ALL

Marieke Hendrika van der Linden, Merel Willekes, Eddy Van Roon, PhD, Pauline Schneider, Rob Pieters, MD, PhD, Ronald Stam, PhD
Journal: Blood
Blood (2012) 120 (21): 1426.
https://doi.org/10.1182/blood.V120.21.1426.1426
Published: 2012
Journal Articles

MLL -Rearranged ALL Cells Are Highly Dependent On the Expression of EP300-Interacting Inhibitor of Differentiation 1 (EID1)

Marieke Hendrika van der Linden, Pauline Schneider, Rob Pieters, MD, PhD, Ronald Stam, PhD
Journal: Blood
Blood (2012) 120 (21): 1462.
https://doi.org/10.1182/blood.V120.21.1462.1462
Published: 2012
Journal Articles

ANGIOPOIETIN1 - a Novel Factor Implicated In MLL-Rearranged Acute Lymphoblastic Leukemia and Regulated In a Fusion Gene-Dependent Manner

Patricia Garrido Castro, Dipl.-Biochem., Simon Bomken, MD, Lidija Seslija, Ronald Stam, PhD, Elda S Latif, Michael A Batey, MPhil, Hesta McNeill, Rob Pieters, MD, PhD, Josef Vormoor, MD, Prof., Johann Greil, MD, Olaf Heidenreich, PhD
Journal: Blood
Blood (2010) 116 (21): 66.
https://doi.org/10.1182/blood.V116.21.66.66
Published: 2010
Journal Articles

Connectivity Mapping Identifies HDAC Inhibitors as Suitable Candidates for the Treatment of t(4;11)-Positive Acute Lymphoblastic Leukemia In Infants

Dominique JPM Stumpel, Pauline Schneider, Lidija Seslija, Hikari Osaki, Owen Williams, Rob Pieters, MD, PhD, Ronald Stam, PhD
Journal: Blood
Blood (2010) 116 (21): 3222.
https://doi.org/10.1182/blood.V116.21.3222.3222
Published: 2010
Journal Articles

Methylation of Specific Microrna Genes In MLL -Rearranged Infant Acute Lymphoblastic Leukemia: - Major Matters at a Micro Scale -

Dominique JPM Stumpel, Diana Schotte, Ellen AM Lange-Turenhout, Pauline Schneider, Lidija Seslija, Renee X de Menezes, Victor E Marquez, Rob Pieters, MD, PhD, Monique L. Den Boer, Ronald Stam, PhD
Journal: Blood
Blood (2010) 116 (21): 2483.
https://doi.org/10.1182/blood.V116.21.2483.2483
Published: 2010
Journal Articles

CD34+CD19−, CD34+CD19+ and CD34−CD19+ Cells May All Have Leukemia-Initiating Potential in NOD/ Scid Mice.

Christoph Le Viseur, Marc Hotfilder, PhD, Annegret Rosemann, Ronald Stam, PhD, Andre Schrauder, MD, Leonard Shultz, PhD, Martin Schrappe, MD, Rob Pieters, MD, Josef Vormoor, MD
Journal: Blood
Blood (2006) 108 (11): 2542.
https://doi.org/10.1182/blood.V108.11.2542.2542
Published: 2006
Journal Articles

A Gene Expression Connectivity Map Identifies Rapamycin as a Glucocorticoid Resistance Reversal Agent in Lymphoblastic Leukemia.

Scott A. Armstrong, MD, PhD, Guo Wei, PhD, Justin Lamb, PhD, Joseph Opferman, PhD, David Twomey, Ronald Stam, PhD, Monique den Boer, PhD, Stephen E. Sallan, MD, Rob Pieters, MD, Todd R. Golub, MD
Journal: Blood
Blood (2005) 106 (11): 108.
https://doi.org/10.1182/blood.V106.11.108.108
Published: 2005