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Roger Grau
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Journal Articles

Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell–mediated B-cell cytotoxicity

Ekkehard Mössner, Peter Brünker, Samuel Moser, Ursula Püntener, Carla Schmidt, Sylvia Herter, Roger Grau, Christian Gerdes, Adam Nopora, Erwin van Puijenbroek, Claudia Ferrara, Peter Sondermann, Christiane Jäger, Pamela Strein, Georg Fertig, Thomas Friess, Christine Schüll, Sabine Bauer, Joseph Dal Porto, Christopher Del Nagro, Karim Dabbagh, Martin J. S. Dyer, Sibrand Poppema, Christian Klein, Pablo Umaña
Journal: Blood
Blood (2010) 115 (22): 4393–4402.
https://doi.org/10.1182/blood-2009-06-225979
Published: 2010
Journal Articles

GA101, a Novel Humanized Type II CD20 Antibody with Glycoengineered Fc and Enhanced Cell Death Induction, Exhibits Superior Anti-Tumor Efficacy and Superior Tissue B Cell Depletion In Vivo.

Pablo Umana, PhD, Moessner Ekkehard, PhD, Bruenker Peter, PhD, Klingner Gabriele, Puentener Ursula, PhD, Tobias Suter, PhD, Roger Grau, PhD, Carla Schmidt, PhD, Sylvia Herter, PhD, Christian Gerdes, PhD, Adam Nopora, PhD, Monika Patre, PhD, Samuel Moser, PhD, Peter Sondermann, PhD, Luise Wheat, PhD, Martin J.S. Dyer, PhD, Sibrand Poppema, PhD, Sabine Bauer, PhD, Manfred Kubbies, PhD, Pamela Strein, PhD, Georg Fertig, PhD, Thomas Friess, PhD, Karim Dabbagh, PhD, Joe DalPorto, PhD, Christian Klein, PhD
Journal: Blood
Blood (2007) 110 (11): 2348.
https://doi.org/10.1182/blood.V110.11.2348.2348
Published: 2007
Journal Articles

Novel 3 rd Generation Humanized Type II CD20 Antibody with Glycoengineered Fc and Modified Elbow Hinge for Enhanced ADCC and Superior Apoptosis Induction.

Pablo Umana, PhD, Ekkehard Moessner, Ph.D., Peter Bruenker, Ph.D., Gabriele Unsin, MSc., Ursula Puentener, MSc., Tobias Suter, Ph.D., Roger Grau, Ph.D., Carla Schmidt, Ph.D., Christian Gerdes, Ph.D., Adam Nopora, Ph.D., Monika Patre, Ph.D., Samuel Moser, MSc., Peter Sondermann, Ph.D., Luise Wheat, Ph.D., Martin J.S. Dyer, Ph.D., Sibrand Poppema, Ph.D., Sabine Bauer, Ph.D., Pamela Strein, Ph.D., Thomas Friess, Ph.D., Christian Klein, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 229.
https://doi.org/10.1182/blood.V108.11.229.229
Published: 2006
Journal Articles

Enhanced Potency of Glycoengineered Anti-CD52 Monoclonal Antibodies (MAbs).

Martin J.S. Dyer, MD, PhD, Samuel Moser, PhD, Peter Brünker, PhD, Pru Bird, PhD, Neil Almond, PhD, Ursula Püentener, PhD, Luise M.W. Wheat, PhD, Emma Bolam, Eleanor Berrie, PhD, Roger Grau, PhD, Emma Buckby, Ben Kennedy, MD, Richard Stebbings, PhD, Geoff Hale, PhD, Pablo Umana, PhD
Journal: Blood
Blood (2005) 106 (11): 2958.
https://doi.org/10.1182/blood.V106.11.2958.2958
Published: 2005