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Richard F Little, MD
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Journal Articles

Ibrutinib and Rituximab Provides Superior Clinical Outcome Compared to FCR in Younger Patients with Chronic Lymphocytic Leukemia (CLL): Extended Follow-up from the E1912 Trial

Tait D. Shanafelt, MD, Victoria Wang, Neil E. Kay, MD, Curtis A. Hanson, MD, Susan M. O'Brien, MD, Jacqueline C. Barrientos, MD MS, Diane F Jelinek, PhD, Esteban Braggio, PhD, Jose F. Leis, MD PhD, Cong Christina Zhang, Steven Coutre, MD, Paul M. Barr, MD, Amanda F Cashen, MD, Anthony R. Mato, MD MSCE, Avina Singh, MD, Michael P. Mullane, MD, Richard F. Little, MD MPH, Harry P. Erba, MD PhD, Richard M. Stone, MD, Mark Litzow, MD, Martin S. Tallman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 33.
https://doi.org/10.1182/blood-2019-126824
Published: 2019
Journal Articles

Potential Factors That Impact Lenalidomide/R-CHOP Efficacy in Previously Untreated Diffuse Large B-Cell Lymphoma in the ROBUST and ECOG-ACRIN 1412 Studies

Grzegorz Nowakowski, MD, Annalisa Chiappella, Fangxin Hong, PhD, Randy D. Gascoyne, MD, David W. Scott, MBChB, PhD, William R. Macon, MD, Rebecca L. King, MD, Jennifer E. Amengual, MD, Richard F. Little, MD MPH, John P. Leonard, MD, Jonathan W. Friedberg, MD, Lale Kostakoglu, MD MPH, Wojciech Jurczak, Kazuhito Yamamoto, Myron Czuczman, Jacqueline Russo, Krista Hudak, PharmD, Jingshan Zhang, PhD, Steve Wade, Thomas E. Witzig, MD, Brad S. Kahl, MD, Umberto Vitolo
Journal: Blood
Blood (2019) 134 (Supplement_1): 4092.
https://doi.org/10.1182/blood-2019-123083
Published: 2019
Journal Articles

Accrual Barriers and Detection of Early Toxicity Signal in Older Less-Fit Patients Treated with Azacitidine and Nivolumab for Newly Diagnosed Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS) in the SWOG 1612 Platform Randomized Phase II/III Clinical Trial

Annette E. Hay, Sarit Assouline, MD, Roland B. Walter, MD PhD MS, Richard F. Little, MD MPH, Anna Moseley, M.S., Sperling M Gail, MPH, CHES, Annie Im, MD, James M. Foran, MD, Jerald P. Radich, MD, Min Fang, MD PhD, Megan Othus, PhD, Harry P. Erba, MD PhD, Laura C. Michaelis, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3905.
https://doi.org/10.1182/blood-2019-124320
Published: 2019
Journal Articles

Comparative Analysis of Immune Reconstitution in HIV-Positive Recipients of Allogeneic and Autologous Stem Cell Transplant on the BMT CTN 0903/AMC-080 and BMT CTN 0803/AMC-071 Trials

Polina Shindiapina, MD PhD, Maciej Pietrzak, PhD, Michal Seweryn, PhD, Eric McLaughlin, MS, Xiaoli Zhang, PhD, Mateusz Makowski, PhD, Justin Lyberger, Hsiaochi Chang, Elshafa Hassan Ahmed, DVM, PhD, Alexander Prouty, BS, Rebecca Pearson, Rhonda Kitzler, Jennifer Le-Rademacher, PhD, Richard F. Little, MD MPH, Gorgun Akpek, MD, Ernesto Ayala, MD, Steven Devine, MD, Ariela Noy, MD, Lawrence D Kaplan, MD, Uday Popat, MD, Jack W. Hsu, MD, Lawrence E Morris, MD, Adam M. Mendizabal, MS, Craig C Hofmeister, MDMPH, William Wachsman, MD PhD, Stephen J Forman, MD, Willis H. Navarro, MD, Joseph C. Alvarnas, MD, Richard F. Ambinder, MD, Gregory K. Behbehani, MD PhD, Gerard Lozanski, MD, Robert A Baiocchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4525.
https://doi.org/10.1182/blood-2019-129488
Published: 2019
Journal Articles

Radiation-Sparing Treatment of HIV-Related Primary Central Nervous System Lymphoma with Antiretroviral Therapy, Rituximab and High-Dose Methotrexate

Kathryn Lurain, MD MPH, Thomas S. Uldrick, MD MS, Priscila H. Goncalves, MD, Ramya Ramaswami, MBBS, MPH, Mark N. Polizzotto, Anaida Widell, Seth M. Steinberg, PhD, Elaine S. Jaffe, Stefania Pittaluga, MD PhD, Maryalice Stetler-Stevenson, MD PhD, Constance M. Yuan, MD PhD, Richard F. Little, MD MPH, Robert Yarchoan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2963.
https://doi.org/10.1182/blood-2018-99-112169
Published: 2018
Journal Articles

Ibrutinib Alone or in Combination with Rituximab Produces Superior Progression Free Survival (PFS) Compared with Bendamustine Plus Rituximab in Untreated Older Patients with Chronic Lymphocytic Leukemia (CLL): Results of Alliance North American Intergroup Study A041202

Jennifer A. Woyach, MD, Amy S. Ruppert, MAS, PhD, Nyla A. Heerema, PhD, Weiqiang Zhao, MD PhD, Allison M Booth, Wei Ding, MD PhD, Nancy L. Bartlett, MD, Danielle M. Brander, MD, Paul Barr, MD, Kerry A. Rogers, MD, Sameer A. Parikh, MD, Steven Coutre, MD, Arti Hurria, MD, Gerard Lozanski, MD, Sreenivasa Nattam, MD, Richard A. Larson, MD, Harry P. Erba, MDPhD, Mark R. Litzow, MD, Carolyn Owen, Jim Atkins, Jeremy S. Abramson, MD MMSc, Richard F. Little, MD MPH, Scott E. Smith, MD PhD, Richard M. Stone, MD, Sumithra J Mandrekar, PhD, John C. Byrd, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 6.
https://doi.org/10.1182/blood-2018-99-116653
Published: 2018
Journal Articles

Dose-Adjusted Teddi-R Induces Durable Complete Remissions in Relapsed and Refractory Primary CNS Lymphoma

Mark Roschewski, MD, Michail S. Lionakis, MD ScD, Christopher Melani, MD, John A. Butman, MD PhD, Stefania Pittaluga, MD PhD, A. Nicole Lucas, RN, Seth M. Steinberg, PhD, Elaine S. Jaffe, Richard F. Little, MD MPH, Louis M. Staudt, MD PhD, Wyndham H. Wilson, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4195.
https://doi.org/10.1182/blood-2018-99-112184
Published: 2018
Journal Articles

Phase I Study of Dose-Adjusted-Teddi-R with Ibrutinib in Untreated and Relapsed/Refractory Primary CNS Lymphoma

Kieron Dunleavy, MD, Catherine E. Lai, MD, Mark Roschewski, MD, Jennifer N Brudno, MD, Brigitte Widemann, MD, Stefania Pittaluga, MD PhD, Elaine S Jaffe, MD, Andrea N Lucas, RN, Maryalice Stetler-Stevenson, MD PhD, Constance M. Yuan, MD PhD, Pamela Harris, MD, Diane Cole, John A Butman, MD, Richard F Little, MD, Louis M Staudt, MD, Wyndham H Wilson, MD PhD
Journal: Blood
Blood (2015) 126 (23): 472.
https://doi.org/10.1182/blood.V126.23.472.472
Published: 2015
Journal Articles

Randomized Phase II Trial of Timed-Sequential Therapy (TST) with Flavopiridol (Alvocidib), Ara-C and Mitoxantrone (FLAM) Versus “7+3” for Adults Ages 70 Years and Under with Newly Diagnosed Acute Myeloid Leukemia (AML)

Joshua F. Zeidner, MD, Jonathan M. Gerber, MD, Amanda Blackford, Mark Litzow, MD, Matthew C. Foster, MD, Lawrence E. Morris, Jr., MD, Ivana Gojo, MD, Jeffrey E. Lancet, MD, Prithviraj Bose, MD, Raoul Tibes, MD, Stephen A. Strickland, MD, MSCI, Jacqueline M Greer, RN, Michelle Drye, Kevin Meads, Austin Doyle, MD, Richard F Little, MD, MPH, John J Wright, MD, PhD, Judith E. Karp, MD
Journal: Blood
Blood (2012) 120 (21): 47.
https://doi.org/10.1182/blood.V120.21.47.47
Published: 2012
Journal Articles

A Pooled Analysis of 1,546 Patients with HIV-Associated Lymphoma: Assessment of Lymphoma-, HIV-, and Treatment-Specific Factors On Clinical Outcomes

Stefan K Barta, MD, MS, MRCP, Xiaonan Xue, Ph.D., Dan Wang, MS, Roni Tamari, MD, Jeannette Y Lee, Ph.D., Nicolas Mounier, MD, PhD, Lawrence D. Kaplan, MD, Josep-Maria Ribera, MD, PhD, Michele Spina, MD, Umberto Tirelli, MD, Rudolf Weiss, MD, Lionel Galicier, MD, Francois Boue, MD, PhD, Wyndham H. Wilson, MD, PhD, Christoph Wyen, MD, Albert Oriol, Jose-Tomas Navarro, MD, PhD, Kieron Dunleavy, MD, Richard F Little, MD, MPH, Lee Ratner, MD, PhD, Olga Garcia, Mireia Morgades, Eric Oksenhendler, MD, Scot Remick, MD, FACP, Joseph A Sparano, MD
Journal: Blood
Blood (2012) 120 (21): 3682.
https://doi.org/10.1182/blood.V120.21.3682.3682
Published: 2012
Journal Articles

Clinical, Immunologic, and Virologic Findings in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Lymphomas Suggest KSHV-Associated Inflammatory Syndromes Contribute to Symptoms and Disease Pathogenesis.

Thomas S Uldrick, MD, MS, Mark N Polizzotto, MBBS, BMedSc, Armando Filie, MD, Karen Aleman, RN, Kathleen M Wyvill, RN, Richard F Little, MD, MPH, Seth M. Steinberg, PhD, Elaine S Jaffe, MD, Denise Whitby, PhD, Stefania Pittaluga, Robert Yarchoan, MD
Journal: Blood
Blood (2012) 120 (21): 2708.
https://doi.org/10.1182/blood.V120.21.2708.2708
Published: 2012
Journal Articles

The Allosteric AKT Inhibitor MK-2206 Demonstrates Potent Antiproliferative Activity in Lymphoma Cells and Synergizes with the HDAC Inhibitor Vorinostat,

Daniela Buglio, MD, PhD, Manuela Lemoine, PhD, Jaymie Estrella, PhD, Sattva S. Neelapu, MD, Richard Eric Davis, MD, Laurence Doyle, MD, Richard F Little, MD, MPH, Donald Berry, Anas Younes, MD
Journal: Blood
Blood (2011) 118 (21): 3729.
https://doi.org/10.1182/blood.V118.21.3729.3729
Published: 2011
Journal Articles

Distinct Human and Viral Interleukin-6 Profiles and Other Viral and Immunologic Abnormalities In KSHV-Associated Multicentric Castleman Disease: Relationship with Disease Activity and Individual Disease Manifestations

Mark N Polizzotto, MBBS, BMedSc, Thomas S Uldrick, MD, MS, Victoria Wang, PhD, Karen Aleman, RN, Kathleen M Wyvill, RN, Vickie Marshall, PhD, Stefania Pittaluga, MD, PhD, Deirdre O'Mahony, MBBS, Denise Whitby, PhD, Giovanna Tosato, PhD, Seth M. Steinberg, PhD, Richard F Little, MD, MPH, Robert Yarchoan, MD
Journal: Blood
Blood (2011) 118 (21): 1573.
https://doi.org/10.1182/blood.V118.21.1573.1573
Published: 2011
Journal Articles

Clinical, Biochemical, and Radiographic Responses to Rituximab Combined with Liposomal Doxorubicin (R-Dox) in HIV-Infected Patients with Severe Kaposi Sarcoma-Associated Herpes Virus (KSHV) – Associated Multicentric Castleman's Disease.

Thomas Uldrick, MD, MS, Mark N. Polizzotto, MBBS, FRACP, FRCPA, Deirdre O'Mahony, Karen Aleman, Kathy Wyvill, Seth Steinberg, PhD, Stefania Pittaluga, MD, Richard F Little, MD, MPH, Robert Yarchoan, MD
Journal: Blood
Blood (2009) 114 (22): 1651.
https://doi.org/10.1182/blood.V114.22.1651.1651
Published: 2009
Journal Articles

Early Results of a Clinical Trial Using Targeted Oncolytic Virotherapy in Kaposi Sarcoma Herpes Virus (KSHV) Associated Multicentric Castleman’s Disease (MCD).

Deirdre O’Mahony, MD, Wendy Bernstein, MD, Kathy Wyvill, RN, Karen Aleman, RN, Denise Whitby, PhD, Seth Steinberg, PhD, Giovanna Tosato, MD, Stefania Pittaluga, MD, Elaine S. Jaffe, MD, Robert Yarchoan, MD, Richard F. Little, MD
Journal: Blood
Blood (2007) 110 (11): 514.
https://doi.org/10.1182/blood.V110.11.514.514
Published: 2007