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Journal Articles

Highly Comprehensive Genomic Testing for CLL: WGS, One Key to CLL Patient Stratification

Kate E Ridout, PhD, Pauline Robbe, MSc, PhD, Doriane Cavalieri, MSc, Jennifer Becq, PhD, Miao He, PhD, Ruth Clifford, FRCPath, PhD, Niamh Appleby, FRCPath, MD, Reem Alsolami, PhD, Adam Burns, BSc, PhD, Melanie Oates, PhD, Basile Stamatopoulos, PhD, Samantha Knight, PhD, Alona Sosinsky, PhD, Pavlos Antoniou, PhD, Mark Ross, PhD, David Bentley, PhD, Andrew Pettitt, FRCPath, PhD, Peter Hillmen, MB ChB, PhD FRCP, FRCPath, Mark Caulfield, PhD, Anna Schuh, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3115.
https://doi.org/10.1182/blood-2018-99-115935
Published: 2018
Journal Articles

Differing Mutational Profiles of IgHV + and IgHV - Patients Revealed By Whole Genome Sequencing in Chronic Lymphocytic Leukaemia (CLL)

Kate Ridout, Reem Alsolami, Adam Burns, Dimitris Vavoulis, Pavlos Antoniou, Peter Hillmen, Samantha JL Knight, Anna Schuh
Journal: Blood
Blood (2016) 128 (22): 5590.
https://doi.org/10.1182/blood.V128.22.5590.5590
Published: 2016
Journal Articles

Identifying High-Risk CLL to Predict Early Relapse after FCR Based Treatment Using Whole Genome Sequencing: First Results from the Genomics England CLL Pilot

Pauline Robbe, Kate Ridout, Jennifer Becq, Miao He, Ruth Clifford, MD, Reem Alsolami, Adam Burns, Samantha JL Knight, Melanie Oates, Dena Howard, Andrew R. Pettitt, Augusto Rendon, Niko Popitsch, Peter Hillmen, Jenny C Taylor, Mark Caulfield, David Bentley, Clare Turnbull, Anna Schuh, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2022.
https://doi.org/10.1182/blood.V128.22.2022.2022
Published: 2016
Journal Articles

Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL

Clinical Trials & Observations
Romain Guièze, Pauline Robbe, Ruth Clifford, Sophie de Guibert, Bruno Pereira, Adele Timbs, Marie-Sarah Dilhuydy, Maite Cabes, Loïc Ysebaert, Adam Burns, Florence Nguyen-Khac, Frédéric Davi, Lauren Véronèse, Patricia Combes, Magali Le Garff-Tavernier, Véronique Leblond, Hélène Merle-Béral, Reem Alsolami, Angela Hamblin, Joanne Mason, Andrew Pettitt, Peter Hillmen, Jenny Taylor, Samantha J. L. Knight, Olivier Tournilhac, Anna Schuh
Journal: Blood
Blood (2015) 126 (18): 2110–2117.
https://doi.org/10.1182/blood-2015-05-647578
Published: 2015
Includes: Supplemental data
Journal Articles

Mutational Landscape of 118 Relapsed Chronic Lymphocytic Leukemia Clinical Trial Samples; Evidence for a Multiple-Hit Profile Using Targeted Next Generation Sequencing

Pauline Robbe, MSc, Romain Guièze, MD, Ruth M Clifford, MD, Sophie de Guibert, Adele Timbs, MSc, Marie-Sarah Dilhuydy, MD, Maite Cabes, BSc, Loic Ysebaert, MDPhD, Adam Burns, BSc, Florence Nguyen-Khac, MDPhD, Frederic Davi, MD PhD, Lauren Veronese, MD PhD, Patricia Combes, Magali Le Garff-Tavernier, MD PhD, Veronique Leblond, MD PhD, Hélène Merle-Béral, MD PhD, Reem Alsolami, MSc, Susanne Weller, PhD, Angela Hamblin, MDPhD, Joanne Mason, PhD, Andrew R Pettitt, MRCP, PhD, Peter Hillmen, MB, ChB, PhD, Jenny Taylor, DPhil, Samantha JL Knight, PhD CBiol, MSB, FRCPath, Anna Schuh, MDPhD, Olivier Tournilhac, MD
Journal: Blood
Blood (2014) 124 (21): 1974.
https://doi.org/10.1182/blood.V124.21.1974.1974
Published: 2014
Journal Articles

Whole Genome Sequencing, Targeted Deep Sequencing and Copy-Number Analysis Provide a Comprehensive Picture of the Mutational Landscape of 41 Clinically Annotated CLL Cases

Adam Burns, BSc, Susanne Weller, PhD, Sean Humphray, PhD, Jennifer Becq, PhD, Reem Alsolami, MSc, Angela Hamblin, MDPhD, Ruth M Clifford, MD, Samantha JL Knight, PhD CBiol, MSB, FRCPath, Pauline Robbe, MSc, Maite Cabes, BSc, Joanne Mason, PhD, Chris S.R Hatton, MD, Jenny Taylor, DPhil, David Bentley, DPhil, Anna Schuh, MDPhD
Journal: Blood
Blood (2014) 124 (21): 1958.
https://doi.org/10.1182/blood.V124.21.1958.1958
Published: 2014
Journal Articles

The Identification of Further Minimal Regions of Overlap in Chronic Lymphocytic Leukemia Using High-Resolution SNP Arrays

Samantha JL Knight, PhD CBiol, MSB, FRCPath, Ruth Clifford, MD, Pauline Robbe, MSc, Sara DC Ramos, MSc, Adam Burns, BSc, Adele T Timbs, MSc, Reem Alsolami, BSc, Susanne Weller, PhD, Angela Hamblin, MDPhD, Joanne Mason, PhD, Melanie Oates, PhD, Michalis Titsias, PhD, Christopher Yau, DPhil, Chris C Holmes, PhD, Andrew R Pettitt, FRCP, PhD, Peter Hillmen, MB, ChB, PhD, Jenny Taylor, DPhil, Anna Shuh, MD PhD FRCP, FRCPath
Journal: Blood
Blood (2014) 124 (21): 3315.
https://doi.org/10.1182/blood.V124.21.3315.3315
Published: 2014
Journal Articles

Towards Response Prediction Using Integrated Genomics in Chronic Lymphocytic Leukaemia: Results on 250 First-Line FCR Treated Patients from UK Clinical Trials

Ruth M Clifford, MD, Pauline Robbe, MSc, Susanne Weller, PhD, Adele T Timbs, MSc, Michalis Titsias, PhD, Adam Burns, BSc, Maite Cabes, BSc, Reem Alsolami, MSc, Christopher Yau, DPhil, Angela Hamblin, MDPhD, Joanne Mason, PhD, Melanie Oates, PhD, Andrew Pettitt, MD PhD, Chris Holmes, PhD, Peter Hillmen, MB, ChB, PhD, Jenny Taylor, DPhil, Samantha JL Knight, PhD CBiol, MSB, FRCPath, Anna Schuh, MDPhD
Journal: Blood
Blood (2014) 124 (21): 1942.
https://doi.org/10.1182/blood.V124.21.1942.1942
Published: 2014