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Journal Articles

Cytokine Rescue and Targeting of Inflammation-Sensitive RUNX1 Deficient Human CD34 + Hematopoietic Stem and Progenitor Cells

Amy Fan, Armon Azizi, BS, Kevin Nuno, BS, Yusuke Nakauchi, MD PhD, Feifei Zhao, MD, Andreas Reinisch, MD PhD, David Cruz Hernandez, MS, Ravindra Majeti, MD PhD

Blood (2020) 136 (Supplement 1): 14–15.

https://doi.org/10.1182/blood-2020-137173

Published: 2020

Journal Articles

Enasidenib Drives Maturation of Human Erythroid Precursors Independently of IDH2

Ritika Dutta, BS, Tian Y Zhang, MD PhD, Thomas Koehnke, MD, Daniel Thomas, MD PhD, Eric Gars, MD, Melissa Stafford, Yusuke Nakauchi, MD PhD, Satinder Kaur, BS, Raymond Yin, Anupama Narla, MD, Ravindra Majeti, MD PhD

Blood (2019) 134 (Supplement_1): 540.

https://doi.org/10.1182/blood-2019-124551

Published: 2019

Journal Articles

Reprogramming Leukemia Cells into Antigen Presenting Cells As a Novel Cancer Vaccination Immunotherapy

Miles Hamilton Linde, BS, BA, Christopher G Dove, Sarah F Gurev, Paul Phan, Feifei Zhao, MD, Lindsay P Miller, Ravindra Majeti, MD PhD

Blood (2019) 134 (Supplement_1): 3217.

https://doi.org/10.1182/blood-2019-128577

Published: 2019

Journal Articles

Human Acute Myeloid Leukemia Inhibits Normal Erythroid Differentiation through the Paracrine Effects of IL-6

Tian Y Zhang, MD PhD, Ritika Dutta, BS, Feifei Zhao, MD, Ravindra Majeti, MD PhD

Blood (2018) 132 (Supplement 1): 911.

https://doi.org/10.1182/blood-2018-99-119297

Published: 2018

Journal Articles

Azacitidine and Ascorbate Inhibit the Competitive Outgrowth of Human TET2 Mutant HSPCs in a Xenograft Model of Pre-Leukemia

Yusuke Nakauchi, MD PhD, Daniel Thomas, MD PhD, Rajiv Sharma, PhD, M. Ryan Corces, PhD, Andreas Reinisch, MD PhD, David Cruz, MS, Thomas Koehnke, MD PhD, Daiki Karigane, MDPhD, Amy Fan, BS, Ravindra Majeti, MD PhD

Blood (2018) 132 (Supplement 1): 887.

https://doi.org/10.1182/blood-2018-99-113907

Published: 2018

Journal Articles

IDH1 Mutant AML Is Susceptible to Targeting De Novo Lipid Synthesis Independent of 2-Hydroxyglutarate and Has a Distinct Metabolic Profile from IDH2 Mutant AML

Daniel Thomas, MD PhD, Yusuke Nakauchi, MD PhD, Manhong Wu, PhD, Ming Zheng, PhD, Subarna Sinha, PhD, David Dill, PhD, Gary Peltz, MD PhD, Ravindra Majeti, MD PhD

Blood (2018) 132 (Supplement 1): 440.

https://doi.org/10.1182/blood-2018-99-115040

Published: 2018

Journal Articles

RBC-Specific CD47 Pruning Confers Protection and Underlies the Transient Anemia in Patients Treated with Anti-CD47 Antibody 5F9

James Y Chen, MD PhD, Kelly Marie McKenna, BS, Timothy S Choi, BS, Jiaqi Duan, MS, Lynette Brown, MSc, Jennifer J Stewart, PhD, Kavitha Sompalli, MS, Paresh Vyas, Stanley Schrier, MD, Ravindra Majeti, MD PhD, Irving L Weissman, MD, Kyle Elrod, BS, Mark Ping Chao, MD PhD, Chris H Takimoto, MD PhD, Jie Liu, PhD MD, Jens-Peter Volkmer, MD

Blood (2018) 132 (Supplement 1): 2327.

https://doi.org/10.1182/blood-2018-99-115674

Published: 2018

Journal Articles

Single-Cell Mutational Profiling of Clonal Evolution in De Novo AML during Therapy and Relapse

Alexey Aleshin, MD MBA, Robert Durruthy-Durruthy, PhD, M. Ryan Corces, PhD, Melissa Stafford, Michaela Liedtke, MD, Bruno C. Medeiros, MD, Dennis J. Eastburn, PhD, Ravindra Majeti, MD PhD

Blood (2018) 132 (Supplement 1): 1469.

https://doi.org/10.1182/blood-2018-99-118089

Published: 2018

Journal Articles

Accumulation of JAK Activation-Loop Phosphorylation Promotes Type I JAK Inhibitor Withdrawal Syndrome in Myelofibrosis

Denis Tvorogov, PhD, Daniel Thomas, MD PhD, Nicholas P.D Liau, Mara Dottore, Emma F Barry, Maya Lathi, Winnie L Kan, PhD, Tim R Hercus, PhD, Frank Stomski, PhD, Timothy P. Hughes, MDMBBS,FRACP,FRCPA, Vinay Tergaonkar, PhD, Michael W Parker, PhD, David M Ross, Jeffrey J Babon, PhD, Ravindra Majeti, MD PhD, Angel F. Lopez, MBBS,PhD

Blood (2018) 132 (Supplement 1): 1787.

https://doi.org/10.1182/blood-2018-99-115760

Published: 2018

Journal Articles

Epigenetic Signature of Leukemia Stem Cells Defines Subgroups Associated with Clinical Outcome and Cell of Origin in AML

Namyoung Jung, BS, Bo Dai, PhD, Andrew J. Gentles, PhD, Peter Murakami, MSc, Ravindra Majeti, MD PhD, Andrew P. Feinberg, MD

Blood (2014) 124 (21): 2147.

https://doi.org/10.1182/blood.V124.21.2147.2147

Published: 2014

Journal Articles

Isocitrate Dehydrogenase Mutations Induce BCL-2 Dependence in Acute Myeloid Leukemia through Inhibition of Cytochrome C Oxidase Function

Steven M. Chan, MD PhD, Daniel Thomas, MD PhD, Bruno C Medeiros, MD, Ravindra Majeti, MD PhD

Blood (2014) 124 (21): 615.

https://doi.org/10.1182/blood.V124.21.615.615

Published: 2014

Journal Articles

Mutation in Wilms' Tumor 1 Induces DNA Hypermethylation of PRC2 Targets, Blocks Myelomonocytic Differentiation, and Defines a Novel Subtype of AML Responsive to EZH2 Inhibition

Daniel Thomas, MD PhD, Subarna Sinha, PhD, Linda Yu, Namyoung Jung, BS, Bo Dai, PhD, Andrew J Gentles, PhD, Andrew P. Feinberg, MD, David Dill, PhD, Ravindra Majeti, MD PhD

Blood (2014) 124 (21): 780.

https://doi.org/10.1182/blood.V124.21.780.780

Published: 2014

Journal Articles

Quantitation of Leukemic Stem Cell Populations Predicts Clinical Outcome in Acute Myeloid Leukaemia

Charles F. Craddock, MD PhD, Nicolas Goardon, PhD, Lynn Quek, MD, Sylvie Freeman, MD, PhD, Shamyla Siddique, Manoj Raghavan, Anna Schuh, PhD, David Grimwade, PhD, Robert K Hills, MA, MSc, DPhil, Cassandra Brookes, PhD, Michael Griffiths, PhD, James D. Cavenagh, MD, Ravindra Majeti, MD, PhD, Irving L. Weissman, MD, Alan K Burnett, MD, Paresh Vyas

Blood (2011) 118 (21): 638.

https://doi.org/10.1182/blood.V118.21.638.638

Published: 2011

Journal Articles

Clonal Evolution of Pre-Leukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia

Max Jan, PhD, Thomas M. Snyder, PhD, M. Ryan Corces-Zimmerman, Irving L. Weissman, Stephen R. Quake, PhD, Ravindra Majeti, MD, PhD

Blood (2011) 118 (21): 4.

https://doi.org/10.1182/blood.V118.21.4.4

Published: 2011

Journal Articles

Is Time of the Essence in Adult Acute Myeloid Leukemia (AML)? Time to Blast Clearance and Time to Induction Therapy Fail to Predict Overall Survival (OS).

Holbrook E Kohrt, MD, Samit Patel, Michelle Ho, Terri Owen, Ravindra Majeti, MD, PhD, Jason R. Gotlib, MD, Steve Coutre, MD, Bruno C. Medeiros, MD, Ash A Alizadeh, MD, PhD

Blood (2009) 114 (22): 1617.

https://doi.org/10.1182/blood.V114.22.1617.1617

Published: 2009

Journal Articles

Single Cell Phospho-Flow Analysis of Cytokine Stimulation in Human Hematopoietic Progenitors Reveals That G-CSF Acts Directly On Human Hematopoietic Stem Cells.

Kenneth Gibbs, Jr., BS, Penney Gilbert, PhD, Irving L. Weissman, MD, Helen M. Blau, PhD, Garry P. Nolan, PhD, Ravindra Majeti, MD, PhD

Blood (2009) 114 (22): 3617.

https://doi.org/10.1182/blood.V114.22.3617.3617

Published: 2009

Journal Articles

Early Mortality in Acute Promyelocytic Leukemia May Be Higher Than Previously Reported.

Ash A Alizadeh, MD, PhD, James S. McClellan, MD, PhD, Jason R. Gotlib, MD, Steven Coutre, MD, Ravindra Majeti, MD, PhD, Holbrook E Kohrt, MD, Bruno C. Medeiros, MD

Blood (2009) 114 (22): 1015.

https://doi.org/10.1182/blood.V114.22.1015.1015

Published: 2009

Journal Articles

Therapeutic Antibody Targeting of CD47 Synergizes with Rituximab to Completely Eradicate Human B-Cell Lymphoma Xenografts.

Mark P. Chao, BA, Ash A Alizadeh, MD, PhD, Chad Z. Tang, MS, June Helen Myklebust, PhD, Bindu Varghese, PhD, Max Jan, BA, Ronald Levy, MD, Irving L. Weissman, MD, Ravindra Majeti, MD, PhD

Blood (2009) 114 (22): 2716.

https://doi.org/10.1182/blood.V114.22.2716.2716

Published: 2009

Journal Articles

CD47 Is An Independent Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

Ravindra Majeti, MD, PhD, Mark P. Chao, Ash A. Alizadeh, MD, PhD, Wendy W. Pang, Irving L. Weissman, MD

Blood (2008) 112 (11): 766.

https://doi.org/10.1182/blood.V112.11.766.766

Published: 2008

Journal Articles

Identification of a Hierarchy of Multipotent Hematopoietic Progenitors in Human Cord Blood.

Ravindra Majeti, MD, PhD, Christopher Y. Park, MD, PhD, Irving L. Weissman, MD

Blood (2007) 110 (11): 2237.

https://doi.org/10.1182/blood.V110.11.2237.2237

Published: 2007

NARROW

Cytokine Rescue and Targeting of Inflammation-Sensitive RUNX1 Deficient Human CD34 + Hematopoietic Stem and Progenitor Cells

Enasidenib Drives Maturation of Human Erythroid Precursors Independently of IDH2

Reprogramming Leukemia Cells into Antigen Presenting Cells As a Novel Cancer Vaccination Immunotherapy

Human Acute Myeloid Leukemia Inhibits Normal Erythroid Differentiation through the Paracrine Effects of IL-6

Azacitidine and Ascorbate Inhibit the Competitive Outgrowth of Human TET2 Mutant HSPCs in a Xenograft Model of Pre-Leukemia

IDH1 Mutant AML Is Susceptible to Targeting De Novo Lipid Synthesis Independent of 2-Hydroxyglutarate and Has a Distinct Metabolic Profile from IDH2 Mutant AML

RBC-Specific CD47 Pruning Confers Protection and Underlies the Transient Anemia in Patients Treated with Anti-CD47 Antibody 5F9

Single-Cell Mutational Profiling of Clonal Evolution in De Novo AML during Therapy and Relapse

Accumulation of JAK Activation-Loop Phosphorylation Promotes Type I JAK Inhibitor Withdrawal Syndrome in Myelofibrosis

Epigenetic Signature of Leukemia Stem Cells Defines Subgroups Associated with Clinical Outcome and Cell of Origin in AML

Isocitrate Dehydrogenase Mutations Induce BCL-2 Dependence in Acute Myeloid Leukemia through Inhibition of Cytochrome C Oxidase Function

Mutation in Wilms' Tumor 1 Induces DNA Hypermethylation of PRC2 Targets, Blocks Myelomonocytic Differentiation, and Defines a Novel Subtype of AML Responsive to EZH2 Inhibition

Quantitation of Leukemic Stem Cell Populations Predicts Clinical Outcome in Acute Myeloid Leukaemia

Clonal Evolution of Pre-Leukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia

Is Time of the Essence in Adult Acute Myeloid Leukemia (AML)? Time to Blast Clearance and Time to Induction Therapy Fail to Predict Overall Survival (OS).

Single Cell Phospho-Flow Analysis of Cytokine Stimulation in Human Hematopoietic Progenitors Reveals That G-CSF Acts Directly On Human Hematopoietic Stem Cells.

Early Mortality in Acute Promyelocytic Leukemia May Be Higher Than Previously Reported.

Therapeutic Antibody Targeting of CD47 Synergizes with Rituximab to Completely Eradicate Human B-Cell Lymphoma Xenografts.

CD47 Is An Independent Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

Identification of a Hierarchy of Multipotent Hematopoietic Progenitors in Human Cord Blood.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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