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Journal Articles

Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM

Roberto Alonso, Mónica López-Guerra, Ramanda Upshaw, Shanta Bantia, Caroline Smal, Françoise Bontemps, Chantal Manz, Thomas Mehrling, Neus Villamor, Elias Campo, Emili Montserrat, Dolors Colomer
Journal: Blood
Blood (2009) 114 (8): 1563–1575.
https://doi.org/10.1182/blood-2009-02-207654
Published: 2009
Includes: Supplemental data
Journal Articles

BCX-4208 (RO5092888), a Purine Nucleoside Phosphorylase (PNP) Inhibitor, Is a Novel, Potent Orally Active Anti-T-Cell and B-Cell Agent.

Shanta Bantia, PhD, Cynthia Parker, Ramanda Upshaw, John Michael Kilpatrick, PhD, Amanda Cunningham, Jianwen Zhang, PhD, Pravin Kotian, PhD, Philip Morris, PhD, Pooran Chand, PhD, Yarlagadda S. Babu, PhD
Journal: Blood
Blood (2008) 112 (11): 1547.
https://doi.org/10.1182/blood.V112.11.1547.1547
Published: 2008
Journal Articles

The Purine Nucleoside Phosphorylase Inhibitor Forodesine (BCX-1777) Is a Potent Cytotoxic Agent and Has Synergistic Activity with Bendamustine in Chronic Lymphocytic Leukemia (CLL) Irrespective of ZAP-70 Levels and p53 Status.

Roberto Alonso, PhD, Neus Villamor, MD, Ramanda Upshaw, BS, Shanta Bantia, PhD, Thomas Mehrling, MD, Elias Campo, MD, Emili Montserrat, MD, Dolors Colomer, PhD
Journal: Blood
Blood (2007) 110 (11): 3122.
https://doi.org/10.1182/blood.V110.11.3122.3122
Published: 2007