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Journal Articles

Aging of Bone Marrow Microenvironment Promotes Myeloid Bias of Hematopoietic Progenitors and Is a Target in Age-Related Myeloproliferative Neoplasms

Blood (2018) 132 (Supplement 1): 3842.

https://doi.org/10.1182/blood-2018-99-116015

Published: 2018

Journal Articles

Ruxolitinib-Induced Defects in DNA Repair Cause Sensitivity to PARP Inhibitors in Myeloproliferative Neoplasms

Margaret Nieborowska-Skorska, Silvia Maifrede, Yashodhara Dasgupta, Katherine Sullivan, Bac Viet Le, Martyna Solecka, Lucia Kubovcakova, Morgan Nawrocki, Martin Kirschner, MD, Huaqing Zhao, Josef T. Prchal, MD, Katarzyna Piwocka, Alison R. Moliterno, MD, Steffen Koschmieder, Anthony R Green, PhD FRCP, FRCPath, FMedSci, Radek C. Skoda, MD, Tomasz Skorski

Blood (2017) 130 (Supplement 1): 2938.

https://doi.org/10.1182/blood.V130.Suppl_1.2938.2938

Published: 2017

Journal Articles

Targeting Cell Non-Autonomous MAPK Activation As a Novel Therapeutic Strategy in Myeloproliferative Neoplasms

Sara C. Meyer, MD PhD, Nilabh Ghosh, MSc, Simona Stivala, PhD, Anne Baerenwaldt, PhD, Hui Hao-Shen, Stefan Dirnhofer, MD, Matthias S. Dettmer, MD, Cédric Simillion, PhD, Sophia Chiu, MSc, Matthew Keller, MSc, Maria Kleppe, PhD, Morgane Hilpert, PhD, Andreas S. Buser, MD, Jakob R. Passweg, MDMS, Thomas Radimerski, PhD, Radek C. Skoda, MD, Ross L. Levine, MD

Blood (2017) 130 (Supplement 1): 381.

https://doi.org/10.1182/blood.V130.Suppl_1.381.381

Published: 2017

Journal Articles

A Gain-of-Function Mutation in EPO Gene Causes Familial Erythrocytosis

Jakub Zmajkovic, MS, Pontus Lundberg, PhD, Ronny Nienhold, PhD, Anders Sundan, PhD, Anders Waage, MD PhD, Radek C. Skoda, MD

Blood (2017) 130 (Supplement 1): 1653.

https://doi.org/10.1182/blood.V130.Suppl_1.1653.1653

Published: 2017

Journal Articles

Effects of the Sympathicomimetic Agonist Mirabegron on Disease Course, Mutant Allele Burden, Marrow Fibrosis, and Nestin Positive Stem Cell Niche in Patients with JAK2 -Mutated Myeloproliferative Neoplasms. a Prospective Multicenter Phase II Trial SAKK 33/14

Beatrice Drexler, MD, Jakob Passweg, MD, Martin Bigler, Alexandre PA Theocharides, MD, Nathan Cantoni, MD, Peter Keller, MD, Georg Stuessi, MD, Axel Rüfer, MD, Rudolf A. Benz, MD, Geneviève Favre, MD, Alexandar Tzankov, MD, Pontus Lundberg, PhD, Andrea Fuhrer, PhD, Christine Biaggi, Markus G Manz, MD, Mario Bargetzi, MD, Simon Mendez-Ferrer, PhD, Radek C. Skoda, MD

Blood (2016) 128 (22): 3108.

https://doi.org/10.1182/blood.V128.22.3108.3108

Published: 2016

Journal Articles

A Study of the Role of Antiplatelet Therapy in the Prevention of Thrombosis in Patients with Calr -Mutated Low Risk Essential Thrombocythemia

Blood (2015) 126 (23): 1602.

https://doi.org/10.1182/blood.V126.23.1602.1602

Published: 2015

Journal Articles

Predisposition to Myeloproliferative Neoplasms

Radek C. Skoda, MD

Blood (2014) 124 (21): SCI-33.

https://doi.org/10.1182/blood.V124.21.SCI-33.SCI-33

Published: 2014

Journal Articles

JAK2V617F and Loss of Ezh2 in Hematopoietic Cells Contribute Synergistically to Myeloproliferative Neoplasm Initiation Potential, and Accelerate Progression of Disease

Takafumi Shimizu, PhD, Hui Hao-Shen, Lucia Kubovcakova, PhD, Pontus Lundberg, PhD, Stephan Dirnhofer, Stuart H. Orkin, MD, Jean Grisouard, PhD, Yukiko Shimizu, Annalisa Pianta, PhD, Barbara Szczerba, Ronny Nienhold, Radek C. Skoda, MD

Blood (2014) 124 (21): 158.

https://doi.org/10.1182/blood.V124.21.158.158

Published: 2014

Journal Articles

JAK2-V617F Expressing Stem Cells Display a Competitive Advantage At Low Limiting Dilution and Are Capable of Initiating MPN Phenotype

Pontus Lundberg, PhD, Lucia Kubovcakova, PhD, Hitoshi Takizawa, PhD, Hui Hao-Shen, Markus G Manz, MD, Radek C. Skoda, MD

Blood (2011) 118 (21): 615.

https://doi.org/10.1182/blood.V118.21.615.615

Published: 2011

Journal Articles

First Achievements of MPN&MPNr-EuroNet (COST Action BM0902), a New European Network Dedicated to the Diagnosis of Myeloproliferative Neoplasms and Hereditary Erythrocytosis and Thrombocytosis

Sylvie Hermouet, MD, PhD, Eric Lippert, PhD, Niels Pallisgaard, Jiri Schwarz, MD, PhD, Mary Frances McMullin, MD, Lars Palmqvist, MD, PhD, Heike L Pahl, Ph.D., Beatriz Bellosillo Paricio, Celeste Bento, Serge Carillo, Stephane Giraudier, MD, PhD, Francois Girodon, MD, PhD, Melanie Percy, PhD, FRCPath, Lukas Plank, Susanne Schnittger, PhD, Radek C. Skoda, MD, Alessandro M. Vannucchi, MD

Blood (2011) 118 (21): 2809.

https://doi.org/10.1182/blood.V118.21.2809.2809

Published: 2011

Journal Articles

In Vivo Imaging of Cerebral Circulation In Mouse Models of Polycythemia Vera

Thom P. Santisakultarm, MS, Nozomi Nishimura, PhD, Claire Paduano, Radek C. Skoda, MD, William L. Olbricht, PhD, Andrew I. Schafer, MD, Chris B. Schaffer, PhD, Richard T. Silver, MD

Blood (2010) 116 (21): 4091.

https://doi.org/10.1182/blood.V116.21.4091.4091

Published: 2010

Journal Articles

Biphasic Roles for the Soluble Guanylyl Cyclase (sGC) In Platelet Activation In Mice

Guoying Zhang, Binggang Xiang, PhD, Radek C. Skoda, MD, Susan S. Smyth, MD, PhD, Xiaoping Du, MD, PhD, Zhenyu Li, MD, PhD

Blood (2010) 116 (21): 486.

https://doi.org/10.1182/blood.V116.21.486.486

Published: 2010

Journal Articles

Acute Panmyelosis with Myelofibrosis: Clinicopathological and Molecular Features of a Rare Malignant Bone Marrow Disease.

Silke Kapp-Schwoerer, Renate Looser, Franz Schaub, Michael Hummel, Manfred Olschewski, Jens Hasskarl, Michael Lübbert, MD, PhD, Ulrich Germing, Radek C. Skoda, MD, Annette H Schmitt-Graeff

Blood (2009) 114 (22): 3101.

https://doi.org/10.1182/blood.V114.22.3101.3101

Published: 2009

Journal Articles

The JAK2-V617F Mutation Load Remains Stable over Several Years in Most Patients with Myeloproliferative Disorders Analyzed in a Retrospective Single Center Study.

Alexandre Theocharides, MD, Renate Looser, Hao-Shen Hui, Andreas S. Buser, MD, Alois Gratwohl, MD, Andre Tichelli, MD, Radek C. Skoda, MD

Blood (2007) 110 (11): 2526.

https://doi.org/10.1182/blood.V110.11.2526.2526

Published: 2007

Journal Articles

Characterization of del20q in Peripheral Blood of MPD Patients Using Copy Number Analysis and High Resolution Oligonucleotide CGH Array

Franz Schaub, MSc, Ralph Tiedt, PhD, Sylvie Hermouet, MD, François Girodon, MD, Robert Kralovics, PhD, André Tichelli, MD, Radek C. Skoda, MD

Blood (2007) 110 (11): 1530.

https://doi.org/10.1182/blood.V110.11.1530.1530

Published: 2007

Journal Articles

Ratio of Mutant JAK2-V617F to Wild Type Jak2 Determines the MPD Phenotypes in Transgenic Mice.

Ralph Tiedt, PhD, Hui Hao-Shen, MSc, Marta A. Sobas, MD, Renate Looser, Stephan Dirnhofer, MD, Jürg Schwaller, MD, Radek C. Skoda, MD

Blood (2007) 110 (11): 674.

https://doi.org/10.1182/blood.V110.11.674.674

Published: 2007

Journal Articles

The JAK2-V617 Mutation Status Identifies Subtypes of Refractory Anemia with Ringed Sideroblasts Associated with Marked Thrombocytosis.

Annette Schmitt-Graeff, MD, Soon-Siong Teo, Manfred Olschewski, Andreas Kirn, MD, Petra Reinecke, MD, Ulrich Germing, MD, Radek C. Skoda, MD, PhD

Blood (2006) 108 (11): 2695.

https://doi.org/10.1182/blood.V108.11.2695.2695

Published: 2006

Journal Articles

Quantitative Analysis of Wild Type and V617F JAK-2 Expression in Neutrophils of Polycythemia Vera and Essential Thrombocythemia Patients at Diagnosis.

Eric Lippert, MD, Francois Girodon, MD, Robert Kralovics, PhD, Marjorie Boissinot, Irene Dobo, Vincent Praloran, MD, Nathalie Boiret, MD, Radek C. Skoda, MD, Sylvie Hermouet, MD

Blood (2005) 106 (11): 257.

https://doi.org/10.1182/blood.V106.11.257.257

Published: 2005

Journal Articles

Gene Expression Profiling Defines a Set of New Molecular Markers for Sporadic and Familial Myeloproliferative Disorders.

Robert Kralovics, PhD, Soon-Siong Teo, Francesco Passamonti, Andreas S. Buser, MD, Andre Tichelli, MD, Mario Cazzola, MD, Radek C. Skoda, MD

Blood (2004) 104 (11): 657.

https://doi.org/10.1182/blood.V104.11.657.657

Published: 2004

Journal Articles

Loss of Heterozygosity on Chromosome 9p24 Is the Most Frequent Chromosomal Aberration in Polycythemia Vera and Idiopathic Myelofibrosis.

Robert Kralovics, PhD, Francesco Passamonti, Kun Liu, Soon-Siong Teo, Anthony Bench, Andre Tichelli, MD, Mario Lazzarino, MD, Anthony R. Green, MD, Mario Cazzola, MD, Radek C. Skoda, MD

Blood (2004) 104 (11): 2425.

https://doi.org/10.1182/blood.V104.11.2425.2425

Published: 2004

NARROW

Aging of Bone Marrow Microenvironment Promotes Myeloid Bias of Hematopoietic Progenitors and Is a Target in Age-Related Myeloproliferative Neoplasms

Ruxolitinib-Induced Defects in DNA Repair Cause Sensitivity to PARP Inhibitors in Myeloproliferative Neoplasms

Targeting Cell Non-Autonomous MAPK Activation As a Novel Therapeutic Strategy in Myeloproliferative Neoplasms

A Gain-of-Function Mutation in EPO Gene Causes Familial Erythrocytosis

Effects of the Sympathicomimetic Agonist Mirabegron on Disease Course, Mutant Allele Burden, Marrow Fibrosis, and Nestin Positive Stem Cell Niche in Patients with JAK2 -Mutated Myeloproliferative Neoplasms. a Prospective Multicenter Phase II Trial SAKK 33/14

A Study of the Role of Antiplatelet Therapy in the Prevention of Thrombosis in Patients with Calr -Mutated Low Risk Essential Thrombocythemia

Predisposition to Myeloproliferative Neoplasms

JAK2V617F and Loss of Ezh2 in Hematopoietic Cells Contribute Synergistically to Myeloproliferative Neoplasm Initiation Potential, and Accelerate Progression of Disease

JAK2-V617F Expressing Stem Cells Display a Competitive Advantage At Low Limiting Dilution and Are Capable of Initiating MPN Phenotype

First Achievements of MPN&MPNr-EuroNet (COST Action BM0902), a New European Network Dedicated to the Diagnosis of Myeloproliferative Neoplasms and Hereditary Erythrocytosis and Thrombocytosis

In Vivo Imaging of Cerebral Circulation In Mouse Models of Polycythemia Vera

Biphasic Roles for the Soluble Guanylyl Cyclase (sGC) In Platelet Activation In Mice

Acute Panmyelosis with Myelofibrosis: Clinicopathological and Molecular Features of a Rare Malignant Bone Marrow Disease.

The JAK2-V617F Mutation Load Remains Stable over Several Years in Most Patients with Myeloproliferative Disorders Analyzed in a Retrospective Single Center Study.

Characterization of del20q in Peripheral Blood of MPD Patients Using Copy Number Analysis and High Resolution Oligonucleotide CGH Array

Ratio of Mutant JAK2-V617F to Wild Type Jak2 Determines the MPD Phenotypes in Transgenic Mice.

The JAK2-V617 Mutation Status Identifies Subtypes of Refractory Anemia with Ringed Sideroblasts Associated with Marked Thrombocytosis.

Quantitative Analysis of Wild Type and V617F JAK-2 Expression in Neutrophils of Polycythemia Vera and Essential Thrombocythemia Patients at Diagnosis.

Gene Expression Profiling Defines a Set of New Molecular Markers for Sporadic and Familial Myeloproliferative Disorders.

Loss of Heterozygosity on Chromosome 9p24 Is the Most Frequent Chromosomal Aberration in Polycythemia Vera and Idiopathic Myelofibrosis.

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American Society of Hematology

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American Society of Hematology

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