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Journal Articles

Recombinant Human Von Willebrand Factor (rhVWF): First-In-Human Study Evaluating Pharmacokinetics, Demonstrating Safety and Tolerability In Type 3 Von Willebrand Disease

Tobias Suiter, MD, Michael Laffan, DM, FRCP, FRCPath, Pier M. Mannucci, MD, Christine L. Kempton, MD, MSc, Edward H Romond, MD, Amy D. Shapiro, MD, Ingvild Birschmann, MD, PhD, Joan Cox Gill, MD, Margaret V. Ragni, MD, MPH, Peter Turecek, PhD, Bruce M. Ewenstein, MD, PhD, VrWF Study Team Baxter BioScience

Blood (2010) 116 (21): 237.

https://doi.org/10.1182/blood.V116.21.237.237

Published: 2010

Journal Articles

Transient Elastography (Fibroscan ® ) In Adult Patients with Inherited Bleeding Disorders and Chronic Hepatitis C.

Maria Elisa Mancuso, MD, PhD, Alessio Aghemo, MD, Paolo Bucciarelli, MD, Elena Santagostino, MD, PhD, Mariagrazia Rumi, MD, Massimo Colombo, MD, Pier M. Mannucci, MD

Blood (2010) 116 (21): 1413.

https://doi.org/10.1182/blood.V116.21.1413.1413

Published: 2010

Journal Articles

A Two-Year Prospective Study on Bleeding Tendency In 105 Patients with Type 2 A and M Von Willebrand Disease

Giancarlo Castaman, MD, Augusto B. Federici, MD, Luciano Baronciani, Pier M. Mannucci, MD, Francesco Rodeghiero

Blood (2010) 116 (21): 543.

https://doi.org/10.1182/blood.V116.21.543.543

Published: 2010

Journal Articles

A Randomized, Double-Blind, Placebo-Controlled, Clinical Outcome Study of ARC1779 In Patients with Thrombotic Thrombocytopenic Purpura (TTP)

Spero R Cataland, MD, Flora Peyvandi, MD, PhD, Pier M. Mannucci, MD, Bernhard Lämmle, Johanna A Kremer Hovinga, MD, Samuel J Machin, Marie Scully, Gail Rock, PhD, MD, FRCP, James Gilbert, MD, Paul Knoebl, Shangbin Yang, PhD, Haifeng Wu, M.D., Bernd Jilma, MD

Blood (2010) 116 (21): 726.

https://doi.org/10.1182/blood.V116.21.726.726

Published: 2010

Journal Articles

Prevalence and Determinants of Bleeding in Severe Von Willebrand Disease Type 3: Results of Retro/Prospective Studies in a Cohort of 105/52 Italian Patients.

Augusto B. Federici, Paolo Bucciarelli, MD, Alfonso Iorio, Giancarlo Castaman, Maria Gabriella Mazzucconi, Massimo Morfini, Angiola Rocino, MD, Pier M. Mannucci, MD

Blood (2009) 114 (22): 3494.

https://doi.org/10.1182/blood.V114.22.3494.3494

Published: 2009

Journal Articles

Circulating Microparticles and Risk of Venous Thromboembolism.

Paolo Bucciarelli, MD, Emanuele Previtali, MD, Ida Martinelli, MD, PhD, Andrea Artoni, MD, Serena M Passamonti, MD, Giuliana Merati, BSc, Armando Tripodi, BSc, Pier M. Mannucci, MD

Blood (2009) 114 (22): 3987.

https://doi.org/10.1182/blood.V114.22.3987.3987

Published: 2009

Journal Articles

Pharmacokinetic Evaluation of a Fibrinogen Concentrate in Patients with Congenital Fibrinogen Deficiency.

Marilyn J. Manco-Johnson, MD, Giancarlo Castaman, MD, Sandra Fremann, MD, Sigurd Knaub, PhD, Gavino Piseddu, MD, Pier M. Mannucci, MD

Blood (2008) 112 (11): 2268.

https://doi.org/10.1182/blood.V112.11.2268.2268

Published: 2008

Journal Articles

Circulating Versus Progenitor Endothelial Cells Levels Are Abnormal in Patients with Different Types of Von Willebrand Disease and Correlate with Markers of Angiogenesis

Giuseppe Gritti, MD, Augusto B Federici, MD, Agostino Cortelezzi, MD, Luciano Baronciani, PhD, Silvia Lonati, PhD, Margherita Punzo, Ilaria Silvestris, Rosanna Garavaglia, MD, Giorgio Lambertenghi, MD, Pier M Mannucci, MD

Blood (2008) 112 (11): 5457.

https://doi.org/10.1182/blood.V112.11.5457.5457

Published: 2008

Journal Articles

Factor V Leiden Is Associated with Premature Myocardial Infarction.

Flora Peyvandi, Marta Spreafico, Luisa Foco, Luisa Bernardinelli, Stefano Duga, Rosanna Asselta, Diego Ardissino, Sekar Kathiresan, Pierangelica Merlini, Pier M. Mannucci, MD

Blood (2008) 112 (11): 1817.

https://doi.org/10.1182/blood.V112.11.1817.1817

Published: 2008

Journal Articles

Relevance of Chloride Binding to Von Willebrand Factor in Type 2B Von Willebrand Disease Patients.

Luciano Baronciani, PhD, Flora Peyvandi, MD, Margherita Punzo, PhD, Maria T. Canciani, PhD, Enrico Di Stasio, MD, Augusto B. Federici, MD, Pier M. Mannucci, MD, Raimondo De Cristofaro, MD

Blood (2008) 112 (11): 3384.

https://doi.org/10.1182/blood.V112.11.3384.3384

Published: 2008

Journal Articles

Von Willebrand Factor-Glycoprotein Ib-Alpha Interactions Play a Role in Generating Platelet Microparticles: Data from Ex Vivo and in Vitro Studies

Andrea Artoni, MD, Anna Lecchi, MariaElisa Mancuso, MD, Elena Santagostino, MD, Augusto Federici, MD, Pier M. Mannucci, MD

Blood (2008) 112 (11): 3920.

https://doi.org/10.1182/blood.V112.11.3920.3920

Published: 2008

Journal Articles

Increased Thrombin Generation in Severe Hemophiliacs with Mild Clinical Phenotype

Elena Santagostino, Maria Elisa Mancuso, Armando Tripodi, Veena Chantarangkul, Gianluigi Pasta, Simona Maria Siboni, Pier M. Mannucci, MD

Blood (2008) 112 (11): 515.

https://doi.org/10.1182/blood.V112.11.515.515

Published: 2008

Journal Articles

Incidence and Determinants of Bleeding in Different Types of von Willebrand Disease: Results of the First Prospective Multicenter Study on 814 Italian Patients.

Augusto B. Federici, MD, Paolo Bucciarelli, MD, Giancarlo Castaman, MD, Maria G. Mazzucconi, MD, Massimo Morfini, MD, Angiola Rocino, MD, Mario Schiavoni, MD, Francesco Rodeghiero, MD, Pier M. Mannucci, MD

Blood (2007) 110 (11): 713.

https://doi.org/10.1182/blood.V110.11.713.713

Published: 2007

Journal Articles

Microparticle Levels Are High in Patients with Hemophilia A and Can Be Further Increased by DDAVP Administration.

Andrea Artoni, MD, PhD, Elena Santagostino, MD PhD, Maria E. Mancuso, MD, Anna Lecchi, BSc, Pier M. Mannucci, MD

Blood (2007) 110 (11): 3139.

https://doi.org/10.1182/blood.V110.11.3139.3139

Published: 2007

Journal Articles

Thrombin Generation in Severe Hemophiliacs with Different Clinical Phenotype.

Elena Santagostino, MD, PhD, Maria E. Mancuso, MD, Armando Tripodi, BSc, Veena Chantarangkul, BSc, Mariagrazia Clerici, BSc, Simona M. Siboni, MD, Pier M. Mannucci, MD

Blood (2007) 110 (11): 1154.

https://doi.org/10.1182/blood.V110.11.1154.1154

Published: 2007

Journal Articles

Thrombin Generation in Severe Hemophiliacs with Different Clinical Phenotype.

Elena Santagostino, MD, Maria E. Mancuso, MD, Armando Tripodi, Veena Chantarangkul, Marigrazia Clerici, Cinzia Sei, Pier M. Mannucci, MD

Blood (2006) 108 (11): 1000.

https://doi.org/10.1182/blood.V108.11.1000.1000

Published: 2006

Journal Articles

Studies with the Nanobody That Detects the Gain-of-Function of von Willebrand Factor in a Cohort of Patients with Type 2B von Willebrand Disease: Correlation with Platelet Count, VWF Multimers and Molecular Defects.

Augusto B. Federici, MD, Luciano Baronciani, PhD, Maria T. Canciani, PhD, Barbara Moroni, PhD, Carlo Balduini, MD, Pier M. Mannucci, MD, Peter J. Lenting, PhD, Philip G. de Groot, PhD

Blood (2006) 108 (11): 1011.

https://doi.org/10.1182/blood.V108.11.1011.1011

Published: 2006

Journal Articles

The αIIbP258S, a Newly Identified Mutation, and the αIIbG349D Substitutions Cause Glanzmann Thrombasthenia by Impairing αIIb-β3 Association in the Endoplasmic Reticulum.

Andrea Artoni, MD, Federica Gelain, MBBS, Abdolreza Afrasiabi, MD, Maurizio Margaglione, MD, Pier M. Mannucci, MD

Blood (2006) 108 (11): 1098.

https://doi.org/10.1182/blood.V108.11.1098.1098

Published: 2006

Journal Articles

Risk Factors for Recurrence of Thrombotic Thrombocytopenic Purpura.

Flora Peyvandi, MD, PhD, Silvia Lavoretano, Roberta Palla, Hendrik B. Feys, Tullia Battaglioli, MD, PhD, Carla Valsecchi, Maria T. Canciani, Fabrizio Fabris, MD, Pier M. Mannucci, MD

Blood (2006) 108 (11): 1060.

https://doi.org/10.1182/blood.V108.11.1060.1060

Published: 2006

Journal Articles

Efficacy and Safety of High-Intermediate-Purity VWF/FVIII Concentrates Given Repeatedly to Severe Patients with Von Willebrand Disease: An Italian Cohort Study on 32 Intensively Treated Cases.

Augusto B. Federici, MD, Belinda J. Cedron, MD, Barbara Scimeca, MD, Maria T. Canciani, PhD, Pier M. Mannucci, MD

Blood (2006) 108 (11): 4060.

https://doi.org/10.1182/blood.V108.11.4060.4060

Published: 2006

NARROW

Recombinant Human Von Willebrand Factor (rhVWF): First-In-Human Study Evaluating Pharmacokinetics, Demonstrating Safety and Tolerability In Type 3 Von Willebrand Disease

Transient Elastography (Fibroscan ® ) In Adult Patients with Inherited Bleeding Disorders and Chronic Hepatitis C.

A Two-Year Prospective Study on Bleeding Tendency In 105 Patients with Type 2 A and M Von Willebrand Disease

A Randomized, Double-Blind, Placebo-Controlled, Clinical Outcome Study of ARC1779 In Patients with Thrombotic Thrombocytopenic Purpura (TTP)

Prevalence and Determinants of Bleeding in Severe Von Willebrand Disease Type 3: Results of Retro/Prospective Studies in a Cohort of 105/52 Italian Patients.

Circulating Microparticles and Risk of Venous Thromboembolism.

Pharmacokinetic Evaluation of a Fibrinogen Concentrate in Patients with Congenital Fibrinogen Deficiency.

Circulating Versus Progenitor Endothelial Cells Levels Are Abnormal in Patients with Different Types of Von Willebrand Disease and Correlate with Markers of Angiogenesis

Factor V Leiden Is Associated with Premature Myocardial Infarction.

Relevance of Chloride Binding to Von Willebrand Factor in Type 2B Von Willebrand Disease Patients.

Von Willebrand Factor-Glycoprotein Ib-Alpha Interactions Play a Role in Generating Platelet Microparticles: Data from Ex Vivo and in Vitro Studies

Increased Thrombin Generation in Severe Hemophiliacs with Mild Clinical Phenotype

Incidence and Determinants of Bleeding in Different Types of von Willebrand Disease: Results of the First Prospective Multicenter Study on 814 Italian Patients.

Microparticle Levels Are High in Patients with Hemophilia A and Can Be Further Increased by DDAVP Administration.

Thrombin Generation in Severe Hemophiliacs with Different Clinical Phenotype.

Thrombin Generation in Severe Hemophiliacs with Different Clinical Phenotype.

Studies with the Nanobody That Detects the Gain-of-Function of von Willebrand Factor in a Cohort of Patients with Type 2B von Willebrand Disease: Correlation with Platelet Count, VWF Multimers and Molecular Defects.

The αIIbP258S, a Newly Identified Mutation, and the αIIbG349D Substitutions Cause Glanzmann Thrombasthenia by Impairing αIIb-β3 Association in the Endoplasmic Reticulum.

Risk Factors for Recurrence of Thrombotic Thrombocytopenic Purpura.

Efficacy and Safety of High-Intermediate-Purity VWF/FVIII Concentrates Given Repeatedly to Severe Patients with Von Willebrand Disease: An Italian Cohort Study on 32 Intensively Treated Cases.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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