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Peter Ruvolo, PhD
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Journal Articles

AXL Inhibitor ONO-9330547 Suppresses PLK1 Gene and Protein Expression and Effectively Induces Growth Arrest and Apoptosis in FLT3 ITD Acute Myeloid Leukemia Cells

Peter Ruvolo, PhD, Huaxian Ma, BS, Vivian Ruvolo, MS, Hong Mu, MD PhD, Wendy Schober, Tomoko Yasuhiro, Toshio Yoshizawa, PhD, Miguel Gallardo, PhD, Xiaorui Zhang, BS, Joseph D Khoury, MD, Jorge Cortes, MD, Michael Andreeff, MD PhD, Sean M. Post, PhD
Journal: Blood
Blood (2016) 128 (22): 3939.
https://doi.org/10.1182/blood.V128.22.3939.3939
Published: 2016
Journal Articles

Targeting Aggregation of Wilde-Type p53 and Mutant p53 with ReACp53 As a Novel Therapeutic Concept for AML

Jianfang Zeng, MD PhD, Alice Soragni, PhD, Jo Ishizawa, MDPhD, Vivian Ruvolo, MS, Christopher B. Benton, MD, Teresa McQueen, MS, Peter Ruvolo, PhD, Yuan Qi, PhD, Xiaoping Su, PhD, Jared Burks, PhD, David S. Eisenberg, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3944.
https://doi.org/10.1182/blood.V128.22.3944.3944
Published: 2016
Journal Articles

Inactivating Heat Shock Factor 1 (HSF1) in Acute Myeloid Leukemia By Pharmacological Inhibition of eIF4a: A Promising Therapeutic Approach

Jo Ishizawa, MD PhD, Rodrigo Omar Jacamo, PhD, Kensuke Kojima, MD PhD, Dhruv Chachad, MS, Vivian Ruvolo, MS, Peter Ruvolo, PhD, Weiguo Zang, PhD, Yoko Tabe, MD PhD, Marina Konopleva, MD PhD, William Devine, PhD, Susan Lindquist, PhD, John A Porco, Jr., Luke Whitesell, MD PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2548.
https://doi.org/10.1182/blood.V126.23.2548.2548
Published: 2015
Journal Articles

Effects of CCL2/CCR2 Blockade in Acute Myeloid Leukemia

Rodrigo Omar Jacamo, PhD, Hong Mu, MD PhD, Qi Zhang, Dhruv Chachad, MS, Wang Zhiqiang, Wencai Ma, PhD, Min Zhang, MD PhD, Po Yee Mak, MPhil, Duncan Mak, BSc, MPhil, Peter Ruvolo, PhD, Teresa McQueen, Scott Lowe, Johannes Zuber, MD PhD, Dirk Eulberg, MBA, Anna Kruschinski, Marina Konopleva, MD PhD, R Eric Davis, MD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1348.
https://doi.org/10.1182/blood.V126.23.1348.1348
Published: 2015
Journal Articles

Role of Mesenchymal Stem Cell Galectin 3 in the AML Tumor Microenvironment

Peter Ruvolo, PhD, Yihua Qiu, MD, Vivian Ruvolo, MS, Rui-Yu Wang, MD PhD, Zhihong Zeng, MD, Jared Burks, PhD, Rongqing Pan, MS, Numsen Hail, Jr., PhD, Teresa McQueen, Suk-Young Yoo, Steven M. Kornblau, MD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1198.
https://doi.org/10.1182/blood.V126.23.1198.1198
Published: 2015
Journal Articles

ONC201 Induces p53-Independent Apoptosis and Abrogates Stem Cell Function in Hematological Malignancies By Induction of ATF4 through Integrated Stress Response

Jo Ishizawa, MD PhD, Kensuke Kojima, MD PhD, Dhruv Chachad, MS, Peter Ruvolo, PhD, Vivian Ruvolo, MS, Rodrigo Omar Jacamo, PhD, Gautam Borthakur, MD, Hong Mu, MD PhD, Zhihong Zeng, MD, Yoko Tabe, MD PhD, Joshua Allen, PhD, Zhiqiang Wang, PhD, Wencai Ma, PhD, Hans Lee, MD, Robert Z. Orlowski, PhD, MD, Dos D. Sarbassov, PhD, Sattva S. Neelapu, MD, Timothy J. McDonnell, MD PhD, Roberto N. Miranda, MD, Michael Wang, MD, Hagop M Kantarjian, MD, Marina Konopleva, MD PhD, Richard Eric Davis, MD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 2051.
https://doi.org/10.1182/blood.V126.23.2051.2051
Published: 2015
Journal Articles

Concurrent Inhibition of Beta-Catenin/CBP and FLT3 Strongly Suppresses c-Myc and Synergistically Induces Apoptosis in FLT3 Mutant AML Cells

Xuejie Jiang, Po Yee Mak, MPhil, Hong Mu, MD PhD, Weiguo Zhang, MD, PhD, Duncan Mak, BSc, MPhil, Peter Ruvolo, PhD, Teresa McQueen, Hongsheng Zhou, Jorge E. Cortes, Michael Andreeff, MD, PhD, Bing Z Carter
Journal: Blood
Blood (2015) 126 (23): 3685.
https://doi.org/10.1182/blood.V126.23.3685.3685
Published: 2015
Journal Articles

Acute Myelogenous Leukemia (AML) Mesenchymal Stromal Cell (MSC) Have Distinct Protein Expression Patterns Compared to Normal MSC

Steven M. Kornblau, MD, Peter Ruvolo, PhD, Rui-Yu Wang, MD PhD, Vivian Ruvolo, MS, Yihua Qiu, MD, Venkata Lokesh Battula, PhD, Zhihong Zeng, MD, Teresa McQueen, Suk-Young Yoo, Marina Konopleva, MD PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 3813.
https://doi.org/10.1182/blood.V126.23.3813.3813
Published: 2015