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Journal Articles

Characterization of Reduced Viscoelasticity in Sickle Cell Disease Mouse Red Blood Cells Using Parallel Plate Rheometry

Nathaniel S Ung, Carlos J Munoz, Krianthan Govender, Daniela Lucas, Cynthia R Muller, Jacinda Martinez, Srila Gopal, Pedro Cabrales

Blood (2024) 144 (Supplement 1): 5293.

https://doi.org/10.1182/blood-2024-212024

Published: 2024

Journal Articles

The Biodistribution of the Novel Heme and Hemoglobin Scavenger Apohemoglobin-Haptoglobin Complex in Healthy C57BL/6 Mice

Daniela Lucas, Carlos J Munoz, Cynthia R Muller, Srila Gopal, Pedro Cabrales

Blood (2023) 142 (Supplement 1): 5269.

https://doi.org/10.1182/blood-2023-190556

Published: 2023

Journal Articles

Investigating the Vasodilatory Effects of Tgpolyhb: A Potential Hemoglobin-Based Oxygen Carrier for Sickle Cell Disease and Thalassemia

Carlos J Munoz, Daniela Lucas, Cynthia R Muller, Srila Gopal, Pedro Cabrales

Blood (2023) 142 (Supplement 1): 5281.

https://doi.org/10.1182/blood-2023-190554

Published: 2023

Journal Articles

Apohemoglobin-Hpatoglobin Promotes Blood Flow in Sickle Cell Disease Mice

Carlos J Munoz, Daniela Lucas, Cynthia R Muller, Srila Gopal, Pedro Cabrales

Blood (2023) 142 (Supplement 1): 3864.

https://doi.org/10.1182/blood-2023-190585

Published: 2023

Journal Articles

Hemoglobin Scavenging Proteins Reduce Free Hemoglobin during Venovenous Extracorporeal Circulation and Reduce Markers of Organ Damage and Inflammation

Krianthan Govender, Derek Lamb, Cynthia Walser, Paul Buehler, Andre Francis Palmer, Robert Owens, Pedro Cabrales

Blood (2023) 142 (Supplement 1): 3845.

https://doi.org/10.1182/blood-2023-190450

Published: 2023

Journal Articles

Preventing Kidney Failure in Hemolytic Anemias with a Novel Heme and Hemoglobin Scavenger

Daniela Lucas, Pedro Cabrales, Carlos J Munoz, Srila Gopal, Cynthia R Muller

Blood (2023) 142 (Supplement 1): 5231.

https://doi.org/10.1182/blood-2023-189876

Published: 2023

Journal Articles

Continuous Dosing of Apohemoglobin-Haptoglobin in Beta Thalassemic Mice to Establish Safety and Efficacy

Carlos J Munoz, Daniela Lucas, Cynthia R Muller, Jacinda Martinez, Krianthan Govender, Srila Gopal, Pedro Cabrales

Blood (2023) 142 (Supplement 1): 5227.

https://doi.org/10.1182/blood-2023-190460

Published: 2023

Journal Articles

Apohemoglobin-Haptoglobin Complex Improves Cardiac and Pulmonary Function in Homozygous Townes (HbSS Townes) Mice

Daniela Lucas, Carlos J Munoz, Cynthia R Muller, Srila Gopal, Pedro Cabrales

Blood (2023) 142 (Supplement 1): 5334.

https://doi.org/10.1182/blood-2023-190581

Published: 2023

Journal Articles

The Effects of Apohemoglobin-Haptoglobin on Heme-Induced Coagulation

Jacinda Martinez, Mia Ricardo, Carlos J Munoz, Daniela Lucas, Cynthia R Muller, Srila Gopal, Pedro Cabrales

Blood (2023) 142 (Supplement 1): 1097.

https://doi.org/10.1182/blood-2023-191248

Published: 2023

Journal Articles

GBT021601 Prevents Microvascular Dysfunction and Improves Hypoxia-Reoxygenation-Induced Vaso-Occlusion in a Murine Model of Sickle Cell Disease

Kobina Dufu, Donna Oksenberg, Brian E Cathers, Carlos J Munoz, Cynthia R Muller, Pedro Pedro Cabrales

Blood (2022) 140 (Supplement 1): 5377–5378.

https://doi.org/10.1182/blood-2022-167797

Published: 2022

Journal Articles

Increased Hemoglobin Affinity for Oxygen with GBT021601 Reduces Pulmonary Hypertension and Lung Vascular Inflammation in a Murine Model of Sickle Cell Disease

Kobina Dufu, Donna Oksenberg, Brian E Cathers, Carlos J Munoz, Cynthia R Muller, Pedro Pedro Cabrales

Blood (2022) 140 (Supplement 1): 5375–5376.

https://doi.org/10.1182/blood-2022-167954

Published: 2022

Journal Articles

Apohemoglobin-Haptoglobin Complex Prevents Microvascular Dysfunction in Sickle Cell Mice: Potential Therapeutic Approach for Vaso-Occlusive Crisis

Carlos J Munoz, Cynthia R Muller, Daniela Lucas, Ivan Susin Pires, Andre F Palmer, Srila Gopal, Pedro Cabrales

Blood (2022) 140 (Supplement 1): 5405–5406.

https://doi.org/10.1182/blood-2022-170559

Published: 2022

Journal Articles

Heme Scavenging with Apohemoglobin-Haptoglobin Complex in Beta Thalassemia Intermedia Improves Anemia and Iron Indices: A Novel Therapeutic Approach

Carlos Jose Munoz, Ivan Susin Pires, Andre F Palmer, Pedro Cabrales, Srila Gopal

Blood (2021) 138 (Supplement 1): 3082.

https://doi.org/10.1182/blood-2021-153017

Published: 2021

Journal Articles

Pharmacological Increase of Hb-O 2 Affinity with a Voxelotor Analog Does Not Decrease Brain Tissue pO 2 or Limit O 2 Extraction in Brain Tissues of Sickle Cell Mice

Kobina Dufu, PhD, Alfredo Lucas, MS, Cynthia Rodrigues Muller, PhD, Alexander T Williams, MS, Xinchun Zhang, MS, Peter Rademacher, PhD, Carsten Alt, MSc, PhD, Donna Oksenberg, PhD, Pedro Cabrales, PhD

Blood (2019) 134 (Supplement_1): 3564.

https://doi.org/10.1182/blood-2019-129282

Published: 2019

Journal Articles

Rrx-001 Is a Phase 3 Small Molecule Dual Inhibitor of CD47 and Sirpα with Activity in Multiple Myeloma

Pedro Cabrales, PhD, Corey Carter, MD, Bryan Oronsky, MD PhD, Tony Reid, MD PhD

Blood (2018) 132 (Supplement 1): 5623.

https://doi.org/10.1182/blood-2018-99-116947

Published: 2018

Journal Articles

GTx011, an Anti-Sickling Compound, Improves SS Blood Rheology By Reduction of HbS polymerization Via Allosteric Modulation of O 2 Affinity

Mira Patel, PhD, Pedro Cabrales, PhD, Kobina Dufu, PhD, Brian Metcalf, PhD, Uma Sinha, PhD

Blood (2014) 124 (21): 1370.

https://doi.org/10.1182/blood.V124.21.1370.1370

Published: 2014

Journal Articles

Dissociation of local nitric oxide concentration and vasoconstriction in the presence of cell-free hemoglobin oxygen carriers

Amy G. Tsai, Pedro Cabrales, Belur N. Manjula, Seetharama A. Acharya, Robert M. Winslow, Marcos Intaglietta

Blood (2006) 108 (10): 3603–3610.

https://doi.org/10.1182/blood-2006-02-005272

Published: 2006

NARROW

Characterization of Reduced Viscoelasticity in Sickle Cell Disease Mouse Red Blood Cells Using Parallel Plate Rheometry

The Biodistribution of the Novel Heme and Hemoglobin Scavenger Apohemoglobin-Haptoglobin Complex in Healthy C57BL/6 Mice

Investigating the Vasodilatory Effects of Tgpolyhb: A Potential Hemoglobin-Based Oxygen Carrier for Sickle Cell Disease and Thalassemia

Apohemoglobin-Hpatoglobin Promotes Blood Flow in Sickle Cell Disease Mice

Hemoglobin Scavenging Proteins Reduce Free Hemoglobin during Venovenous Extracorporeal Circulation and Reduce Markers of Organ Damage and Inflammation

Preventing Kidney Failure in Hemolytic Anemias with a Novel Heme and Hemoglobin Scavenger

Continuous Dosing of Apohemoglobin-Haptoglobin in Beta Thalassemic Mice to Establish Safety and Efficacy

Apohemoglobin-Haptoglobin Complex Improves Cardiac and Pulmonary Function in Homozygous Townes (HbSS Townes) Mice

The Effects of Apohemoglobin-Haptoglobin on Heme-Induced Coagulation

GBT021601 Prevents Microvascular Dysfunction and Improves Hypoxia-Reoxygenation-Induced Vaso-Occlusion in a Murine Model of Sickle Cell Disease

Increased Hemoglobin Affinity for Oxygen with GBT021601 Reduces Pulmonary Hypertension and Lung Vascular Inflammation in a Murine Model of Sickle Cell Disease

Apohemoglobin-Haptoglobin Complex Prevents Microvascular Dysfunction in Sickle Cell Mice: Potential Therapeutic Approach for Vaso-Occlusive Crisis

Heme Scavenging with Apohemoglobin-Haptoglobin Complex in Beta Thalassemia Intermedia Improves Anemia and Iron Indices: A Novel Therapeutic Approach

Pharmacological Increase of Hb-O 2 Affinity with a Voxelotor Analog Does Not Decrease Brain Tissue pO 2 or Limit O 2 Extraction in Brain Tissues of Sickle Cell Mice

Rrx-001 Is a Phase 3 Small Molecule Dual Inhibitor of CD47 and Sirpα with Activity in Multiple Myeloma

GTx011, an Anti-Sickling Compound, Improves SS Blood Rheology By Reduction of HbS polymerization Via Allosteric Modulation of O 2 Affinity

Dissociation of local nitric oxide concentration and vasoconstriction in the presence of cell-free hemoglobin oxygen carriers

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American Society of Hematology

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ASH Publications

American Society of Hematology

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