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Journal Articles

A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-Cells

Irene Cortese, Austin John Barrett, David F. Stroncek, Steven Highfill, PhD, Erin Beck, Frances Andrada, Joan Ohayon, Jennifer Dwyer, Matthew Schindler, Georg Aue, Daniel Reich, Avindra Nath, Pawel Muranski, MD

Blood (2018) 132 (Supplement 1): 4535.

https://doi.org/10.1182/blood-2018-99-119832

Published: 2018

Journal Articles

Efficient Expansion of Polyfunctional Virus-Specific T Cells from Human Lymph Nodes: Implications for Cellular Therapies

Stuart P. Weisberg, MD PhD, Mark Chang, Pawel Muranski, MD, Donna Farber, PhD

Blood (2018) 132 (Supplement 1): 3715.

https://doi.org/10.1182/blood-2018-99-116507

Published: 2018

Journal Articles

Very Early Adoptive Transfer of Ex Vivo Generated Multi-Virus Specific T Cells Is a Safe Strategy for Prevention of Viral Infection after Allogeneic T Cell Depleted Stem Cell Transplantation

Pawel Muranski, MD, Sarah I Davies, Sawa Ito, MD, Eleftheria Koklanaris, RN, Jeanine Superata, RN, Quan Yu, Steven L Highfill, PhD, Marianna Sabatino, MD, David F. Stroncek, Minoo Battiwalla, MD, Austin John Barrett

Blood (2018) 132 (Supplement 1): 812.

https://doi.org/10.1182/blood-2018-99-119314

Published: 2018

Journal Articles

Neoantigen Landscape of Relapsed Acute Leukemia Following Allogeneic Stem Cell Transplantation

Karolyn Oetjen, MD, Cai Chen, Christian Bradley, BS, Reema Panjwani, BS, Cheng Yan, Minoo Battiwalla, MD, Pawel Muranski, MD, Austin John Barrett, Sawa Ito, MD

Blood (2018) 132 (Supplement 1): 4595.

https://doi.org/10.1182/blood-2018-99-115501

Published: 2018

Journal Articles

Safety and Feasibility of Ultra-Low Dose IL-2 As Graft Versus Host Disease Prophylaxis in Haplo-Identical Stem Cell Transplantation- a Proof of Concept Pilot Study

Sawa Ito, MD PhD, Prachi Jain, MD, Caroline R Cantilena, BA, Prathima Anandi, MD, Kit Lu, MD, Fariba Chinian, Debbie Draper, RN, Libby Koklanaris, RN, Sara Hauffe, RN, Jeanine Superata, RN, Andra Krauze, MD, David Stroncek, MD, Adams Sharon, MT, Thomas E. Hughes, PharmD, Pawel Muranski, MD, Minoo Battiwalla, MDMS, John Barrett, MD

Blood (2016) 128 (22): 386.

https://doi.org/10.1182/blood.V128.22.386.386

Published: 2016

Journal Articles

Clofarabine Followed By Lenalidomide for Treatment of High Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia- Preliminary Clinical Outcomes and Potential Immune-Modulating Effects

Prachi Jain, MD, Sawa Ito, MD PhD, Neil Dunavin, MD, Jeffrey K. Klotz, MD, Kit Lu, MD, Eleftheria Koklanaris, RN, BSN, Debbie Draper, RN, BSN, Jeanine Superata, RN, Fariba Chinian, Quan Yu, MS, Keyvan Keyvanfar, BS, Susan Wong, Pawel Muranski, MD, John Barrett, MD, Minoo Battiwalla, MDMS

Blood (2016) 128 (22): 5553.

https://doi.org/10.1182/blood.V128.22.5553.5553

Published: 2016

Journal Articles

Reduced Non Relapse Mortality (NRM) and Survivable Acute Graft Versus Host Disease (GVHD) in the Current Era of Myeloablative Ex Vivo T-Cell Depleted (TCD) Transplantation

Natasha A Jain, MD, Prathima Anandi, MD, Upneet Chawla, BS, MD, Sawa Ito, MD PhD, Debbie Draper, RN, Eleftheria Koklanaris, RN, Sara Hauffe, RN, Jeanine Superata, RN, Robert Q. Le, MD PhD, David Stroncek, MD, Pawel Muranski, MD, Minoo Battiwalla, MD MS, John Barrett, MD

Blood (2016) 128 (22): 4596.

https://doi.org/10.1182/blood.V128.22.4596.4596

Published: 2016

Journal Articles

Early Adoptive Transfer of Ex Vivo Generated Multi-Virus Specific T Cells Is a Safe Strategy to Prevent Viral Reactivation in Recipients of Allogeneic T Cell Depleted Stem Cell Transplant

Pawel Muranski, MD, Greg Whitehill, BS, Debbie Draper, RN, Eleftheria Koklanaris, RN, Jeanine Superata, RN, Quan Yu, MS, Marianna Sabatino, MD, Steven L. Highfill, PhD, Hanh Khuu, MD, Sarah I Davies, Mark Chang, Upneet Chawla, BS, MD, Alexandros Spyridonidis, MD PhD, Gary Fahle, MT,SM, Sawa Ito, MD PhD, David Stroncek, MD, Minoo Battiwalla, MDMS, John Barrett, MD

Blood (2016) 128 (22): 979.

https://doi.org/10.1182/blood.V128.22.979.979

Published: 2016

Journal Articles

Distinct Biomarker Profiles in Ex-Vivo T Cell Depletion Graft Manipulation Strategies: CD34+ Selection Vs CD3/19 Depletion in Matched Sibling Allogeneic Peripheral Blood Stem Cell Transplantation

Caroline R. Cantilena, BA, Sawa Ito, MD PhD, Xin Tian, Prachi Jain, MD, Fariba Chinian, Prathima Anandi, MD, Upneet Chawla, BS, MD, Debbie Draper, RN, Eleftheria Koklanaris, RN, Jeanine Superata, RN, David Stroncek, MD, Pawel Muranski, MD, John Barrett, MD, Minoo Battiwalla, MDMS

Blood (2016) 128 (22): 657.

https://doi.org/10.1182/blood.V128.22.657.657

Published: 2016

Journal Articles

Association of Comprehensive Lipoprotein Profiling with Coronary Artery Disease in Allogeneic Stem Cell Transplant (Allo-SCT) Survivors

Upneet Chawla, BS, MD, Maureen Sampson, MT, Natasha A Jain, MD, Prathima Anandi, MD, Sawa Ito, MD PhD, Eleftheria Koklanaris, RN, Pawel Muranski, MD, John Barrett, MD, Marcus Y Chen, MD, Alan Remaley, MD PhD, Minoo Battiwalla, MDMS

Blood (2016) 128 (22): 828.

https://doi.org/10.1182/blood.V128.22.828.828

Published: 2016

Journal Articles

Selective Depletion of Alloreactive Donor T Cells with Adenosine: An Efficient, Scaleable, GMP-Compliant, Low-Cost Method to Prevent Gvhd While Preserving Antiviral and Antileukemic Activity in Haploidentical Stem Cell Transplant

Greg Whitehill, BS, Shoba Amarnath, BSc, MSc, PhD, Keyvan Keyvanfar, BS, Pawel Muranski, MD, Minoo Battiwalla, MDMS, Austin John Barrett, MDFRCP,FRCPath, Dhana Chinnasamy, PhD

Blood (2015) 126 (23): 380.

https://doi.org/10.1182/blood.V126.23.380.380

Published: 2015

Journal Articles

High Frequency of Circulating CD8 + Memory Stem T Cells in Acquired Aplastic Anemia

Kohei Hosokawa, MDPhD, Pawel Muranski, MD, Xingmin Feng, PhD, Danielle M. Townsley, MD, Baoying Liu, PhD, Jared Knickelbein, MD, Keyvan Keyvanfar, BS, Bogdan Dumitriu, MD, Sawa Ito, MD, Sachiko Kajigaya, PhD, James G. Taylor, MD, Mariana J. Kaplan, MD, Robert B. Nussenblatt, MD, Austin John Barrett, MDFRCP,FRCPath, John O'Shea, MD, Neal S. Young, MD

Blood (2015) 126 (23): 3613.

https://doi.org/10.1182/blood.V126.23.3613.3613

Published: 2015

Journal Articles

Adoptive T Cell Therapy for Polyomaviral Infections and Related Diseases

Dhana Chinnasamy, PhD, Greg Whitehill, BS, Keyvan Keyvanfar, BS, Isaac Brownell, MD PhD, Christopher Buck, PhD, Pawel Muranski, MD, Austin John Barrett, MDFRCP,FRCPath

Blood (2015) 126 (23): 4294.

https://doi.org/10.1182/blood.V126.23.4294.4294

Published: 2015

Journal Articles

Altered microRNAs in T Cells from Patients with Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Pawel Muranski, MD, Xingmin Feng, PhD, Keyvan Keyvanfar, BS, Danielle M. Townsley, MD, Bogdan Dumitriu, MD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, James G. Taylor, MD, Christopher S. Hourigan, MD PhD, John Barrett, MD, Neal S. Young, MD

Blood (2014) 124 (21): 2940.

https://doi.org/10.1182/blood.V124.21.2940.2940

Published: 2014

Journal Articles

A Novel Standardized Quantitative Suppression Assay Reveals a Diversity of Human Immune-Regulatory Cell Potency

Samantha Miner, Nancy F. Hensel, Bahey Salem, Neil Dunavin, MD, Kazushi Tanimoto, MD, Minoo Battiwalla, MD MS, Kit Lu, MD, Keyvan Keyvanfar, BS, Marianna Sabatino, David Stroncek, Patrick J Hanley, PhD, Catherine M. Bollard, MBChB, MD, Katayoun Rezvani, MD, PhD, Marcin Kortylewski, PhD, Pawel Muranski, MD, John Barrett, MD, Sawa Ito, MD

Blood (2014) 124 (21): 316.

https://doi.org/10.1182/blood.V124.21.316.316

Published: 2014

Journal Articles

A Suppressive Microenvironment in Acute Myeloid Leukemia Induces Global Alteration of T and NK Cell Profiles - Evidence for Immune-Editing Effect By Leukemia

Sawa Ito, MD, John Barrett, MD, Bipin N. Savani, MD, Madan Jagasia, MBBS, MS, Eolia Brissot, Samantha Miner, Nancy F. Hensel, Fariba Chinian, M.S., Keyvan Keyvanfar, BS, Minoo Battiwalla, MD MS, Michael R Savona, MD, Sanjay Mohan, MD, Mattias Carlsten, MD PhD, Pawel Muranski, MD, Stephen A. Strickland, MD MSCI

Blood (2014) 124 (21): 1047.

https://doi.org/10.1182/blood.V124.21.1047.1047

Published: 2014

Journal Articles

Ex Vivo Generation of CD4 + Th17 Cells to Prevent and Treat Infection from Antibiotic-Resistant Klebsiella Pneumoniae in Immunocompromised Patients

Pawel Muranski, MD, Manuel Franco-Colon, Dhanalakshmi Chinnasamy, Kong Chen, Scott Stegemann, Jinwen Sui, Sawa Ito, MD, Marianna Sabatino, MD, David F. Stroncek, MD, Tara Palmore, Jay Kolls, A John Barrett, MD

Blood (2014) 124 (21): 2445.

https://doi.org/10.1182/blood.V124.21.2445.2445

Published: 2014

Journal Articles

T Cell Exhaustion and Downregulation of Cytotoxic NK Cells – an Immune Escape Mechanism in Adult Acute Lymphoblastic Leukemia

Eolia Brissot, Sawa Ito, MD, Kit Lu, MD, Carly Cantilena, B. Douglas Smith, Gabrielle Prince, Hossein Sadrzadeh, Amir T Fathi, Stephen A. Strickland, MD MSCI, Nancy F. Hensel, Fariba Chinian, M.S., Keyvan Keyvanfar, BS, Minoo Battiwalla, MDMS, Pawel Muranski, MD, Christopher S. Hourigan, MDPhD, John Barrett, MD

Blood (2014) 124 (21): 3781.

https://doi.org/10.1182/blood.V124.21.3781.3781

Published: 2014

Journal Articles

Alemtuzumab Achieved Durable Hematologic Response In Heavily Treated T-Large Granular Lymphocytosis Irrespective To STAT3 Mutation Or V-Beta Clone Size

Bogdan Dumitriu, MD, Phillip Scheinberg, MD, Sawa Ito, Nicole Stephens, BS, Yunce Muharrem, MD, Emily King, Sachiko Kajigaya, PhD, J. Joseph Melenhorst, PhD, Fariba Chinian, M.S., Keyvan Keyvanfar, BS, Minoo Battiwalla, MD, MS, Pawel Muranski, MD, Neal S. Young, MD, A. John Barrett

Blood (2013) 122 (21): 3705.

https://doi.org/10.1182/blood.V122.21.3705.3705

Published: 2013

Journal Articles

Myeloid Leukemias Directly Suppress T Cell Proliferation Through STAT3 and Arginase Pathways

Samantha Miner, B.S., Sawa Ito, Kazushi Tanimoto, MD, Nancy F. Hensel, Fariba Chinian, M.S., Keyvan Keyvanfar, BS, Christopher S. Hourigan, MD, PhD, Minoo Battiwalla, MD, MS, J. Joseph Melenhorst, PhD, Pawel Muranski, MD, A. John Barrett

Blood (2013) 122 (21): 3885.

https://doi.org/10.1182/blood.V122.21.3885.3885

Published: 2013

NARROW

A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-Cells

Efficient Expansion of Polyfunctional Virus-Specific T Cells from Human Lymph Nodes: Implications for Cellular Therapies

Very Early Adoptive Transfer of Ex Vivo Generated Multi-Virus Specific T Cells Is a Safe Strategy for Prevention of Viral Infection after Allogeneic T Cell Depleted Stem Cell Transplantation

Neoantigen Landscape of Relapsed Acute Leukemia Following Allogeneic Stem Cell Transplantation

Safety and Feasibility of Ultra-Low Dose IL-2 As Graft Versus Host Disease Prophylaxis in Haplo-Identical Stem Cell Transplantation- a Proof of Concept Pilot Study

Clofarabine Followed By Lenalidomide for Treatment of High Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia- Preliminary Clinical Outcomes and Potential Immune-Modulating Effects

Reduced Non Relapse Mortality (NRM) and Survivable Acute Graft Versus Host Disease (GVHD) in the Current Era of Myeloablative Ex Vivo T-Cell Depleted (TCD) Transplantation

Early Adoptive Transfer of Ex Vivo Generated Multi-Virus Specific T Cells Is a Safe Strategy to Prevent Viral Reactivation in Recipients of Allogeneic T Cell Depleted Stem Cell Transplant

Distinct Biomarker Profiles in Ex-Vivo T Cell Depletion Graft Manipulation Strategies: CD34+ Selection Vs CD3/19 Depletion in Matched Sibling Allogeneic Peripheral Blood Stem Cell Transplantation

Association of Comprehensive Lipoprotein Profiling with Coronary Artery Disease in Allogeneic Stem Cell Transplant (Allo-SCT) Survivors

Selective Depletion of Alloreactive Donor T Cells with Adenosine: An Efficient, Scaleable, GMP-Compliant, Low-Cost Method to Prevent Gvhd While Preserving Antiviral and Antileukemic Activity in Haploidentical Stem Cell Transplant

High Frequency of Circulating CD8 + Memory Stem T Cells in Acquired Aplastic Anemia

Adoptive T Cell Therapy for Polyomaviral Infections and Related Diseases

Altered microRNAs in T Cells from Patients with Acquired Aplastic Anemia

A Novel Standardized Quantitative Suppression Assay Reveals a Diversity of Human Immune-Regulatory Cell Potency

A Suppressive Microenvironment in Acute Myeloid Leukemia Induces Global Alteration of T and NK Cell Profiles - Evidence for Immune-Editing Effect By Leukemia

Ex Vivo Generation of CD4 + Th17 Cells to Prevent and Treat Infection from Antibiotic-Resistant Klebsiella Pneumoniae in Immunocompromised Patients

T Cell Exhaustion and Downregulation of Cytotoxic NK Cells – an Immune Escape Mechanism in Adult Acute Lymphoblastic Leukemia

Alemtuzumab Achieved Durable Hematologic Response In Heavily Treated T-Large Granular Lymphocytosis Irrespective To STAT3 Mutation Or V-Beta Clone Size

Myeloid Leukemias Directly Suppress T Cell Proliferation Through STAT3 and Arginase Pathways

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American Society of Hematology

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American Society of Hematology

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