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Patrick P. Zarrinkar
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Journal Articles

AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML)

Patrick P. Zarrinkar, Ruwanthi N. Gunawardane, Merryl D. Cramer, Michael F. Gardner, Daniel Brigham, Barbara Belli, Mazen W. Karaman, Keith W. Pratz, Gabriel Pallares, Qi Chao, Kelly G. Sprankle, Hitesh K. Patel, Mark Levis, Robert C. Armstrong, Joyce James, Shripad S. Bhagwat
Journal: Blood
Blood (2009) 114 (14): 2984–2992.
https://doi.org/10.1182/blood-2009-05-222034
Published: 2009
Includes: Supplemental data
Journal Articles

Phase 1 AML Study of AC220, a Potent and Selective Second Generation FLT3 Receptor Tyrosine Kinase Inhibitor

Jorge E. Cortes, Darejan Ghirdaladze, James M. Foran, Marcel P. DeVetten, Mamia Zodelava, Mark J. Levis, Norman M. Padre, James Joyce, Patrick P. Zarrinkar, Robert Corringham
Journal: Blood
Blood (2008) 112 (11): 767.
https://doi.org/10.1182/blood.V112.11.767.767
Published: 2008
Journal Articles

AC220 Is a Uniquely Potent and Selective Second-Generation FLT3 Inhibitor

Patrick P Zarrinkar, PhD, Robert C Armstrong, Ph.D., Ruwanthi N Gunawardane, Ph.D., Joyce James, PhD, Mazen W Karaman, Ph.D., Shripad S Bhagwat, PhD
Journal: Blood
Blood (2008) 112 (11): 859.
https://doi.org/10.1182/blood.V112.11.859.859
Published: 2008
Journal Articles

Clinical Pharmacokinetics and FLT3 Phosphorylation of AC220, a Highly Potent and Selective Inhibitor of FLT3

Joyce James, PhD, Keith Pratz, Adam Stine, Julius L Apuy, PhD, Darren E Insko, PhD, Robert C Armstrong, Ph.D., Patrick P Zarrinkar, PhD, Donald Small, MD, PhD, Wendell Wierenga, PhD, Mark J. Levis, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2637.
https://doi.org/10.1182/blood.V112.11.2637.2637
Published: 2008
Journal Articles

Human Pharmacokinetics of AC220, a Potent and Selective Class III Receptor Tyrosine Kinase Inhibitor.

Jorge Cortes, James M. Foran, Marcel P. Devetten, Francis J. Giles, Joyce James, Patrick P. Zarrinkar, Michael H. Silverman, Kerry A. Kelly, Norman M. Padre, Shripad Bhagwat, Wendell Wierenga
Journal: Blood
Blood (2007) 110 (11): 1597.
https://doi.org/10.1182/blood.V110.11.1597.1597
Published: 2007