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Journal Articles

GDF15 and Erythroferrone Mark Erythropoietic Response to ACE-011 (Sotatercept) in Thalassemia

Blood (2018) 132 (Supplement 1): 3633.

https://doi.org/10.1182/blood-2018-99-111770

Published: 2018

Journal Articles

Iron Level and Monocyte Morphology Predict TLR4 Expression and Reactive Oxygen Species Production Which Influences Chronic Inflammation in β-Thalassemia

Patrick B. Walter, PhD, Nick Slater, BS, Paul Harmatz, MD, Annie Higa, BS, Vivian Ng, BS, Marcels Weyhmiller, Patricia Evans, PhD, John B Porter, Nancy Sweeters, Jackson Price, BS, David Killilea, PhD, Lynne Neumayr, MD, Ashutosh Lal, MD, Elliott Vichinsky, MD

Blood (2015) 126 (23): 950.

https://doi.org/10.1182/blood.V126.23.950.950

Published: 2015

Journal Articles

Residual Erythropoiesis Protects Against Cardiac Iron Loading in Transfusion Dependent Thalassaemia (TDT) By Lowering Labile Plasma Iron (LPI) through Transient Apotransferrin Generation

Maciej W. Garbowski, MD, Patricia Evans, PhD, John B Porter

Blood (2015) 126 (23): 539.

https://doi.org/10.1182/blood.V126.23.539.539

Published: 2015

Journal Articles

Association Of Cardiac Iron By T2* With Innate Immune Markers In Transfusion-Dependent Thalassemia Patients Undergoing Combined Chelation Therapy

Patrick B Walter, PhD, Annie Higa, BS, Vivian Ng, B.S., Marcela G Weyhmiller, PhD, Nick R Slater, Patricia Evans, PhD, John B Porter, MD, Nancy Sweeters, RN, PNP, Jackson Price, B.S., Alisha Manji, B.S., David Killilea, PhD, Ashutosh Lal, MD, Elliott Vichinsky, MD

Blood (2013) 122 (21): 3450.

https://doi.org/10.1182/blood.V122.21.3450.3450

Published: 2013

Journal Articles

Determinants Of Tissue Iron Loading In Transfused and Non-Transfused β-Thalassemia and Sickle Cell Disease Patients – Biomarkers Of Iron Regulation and Inflammation

Patrick B Walter, PhD, Zahra Pakbaz, MD, Elizabeta Nemeth, PhD, Tomas Ganz, MD, PhD, John B Porter, MD, Patricia Evans, PhD, Kelsey M Houston, Roland Fischer, PhD, Marcela G Weyhmiller, PhD, Matt Herz, Bs, Jeffery L Miller, MD, Robert Hagar, MD, Lynne D Neumayr, MD, Elliott Vichinsky, MD, Paul Harmatz, MD

Blood (2013) 122 (21): 1017.

https://doi.org/10.1182/blood.V122.21.1017.1017

Published: 2013

Journal Articles

Inflammatory and Vitamin Bio-Markers Of Iron Trafficking and Distribution In Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia With Sickle Cell Disease and Thalassemia (MCSIO PILOT Study)

John Porter, MD, Patrick B Walter, PhD, Lynne D Neumayr, MD, Patricia Evans, PhD, Marcela G Weyhmiller, PhD, Paul Harmatz, MD, John C. Wood, MD, PhD, Jeffery L Miller, MD, Guenter Weiss, MD, Quing Yuan, PhD, Zhiyue J Wang, PhD, Regine Grosse, MD, Bjoern P Schoennagel, MD, Joerg Meerpohl, MD, Roland Fischer, PhD, Peter Nielsen, MD, Markus Seifert, BSc, Elliott Vichinsky, MD

Blood (2013) 122 (21): 1014.

https://doi.org/10.1182/blood.V122.21.1014.1014

Published: 2013

Journal Articles

Innate Immune Cell Expression of Pattern Recognition Receptors From β-Thalassemia Patients During Intensive Combination Chelation Therapy

Patrick B Walter, PhD, Paul Harmatz, MD, Annie Higa, B.S., Vivian Ng, B.S., Marcela G Weyhmiller, PhD, Patricia Evans, PhD, John B. Porter, MD, Nancy Sweeters, RN, PNP, Jackson Price, B.S., Alisha Manji, B.S., David Killilea, PhD, Ashutosh Lal, MD, Elliott Vichinsky, MD

Blood (2012) 120 (21): 1025.

https://doi.org/10.1182/blood.V120.21.1025.1025

Published: 2012

Journal Articles

Metabolomic Biomarkers As Predictors of Iron Load and Oxidative Damage in Iron Overloaded Thalassemia Patients

Farzana Sayani, MD FRCPC, Ying Zhang, MSc, Niloufar Abdolmohammadi, Anne Marie Lauf, Patricia Evans, PhD, John B. Porter, MD, Aalim Mahdi Weljie, PhD

Blood (2012) 120 (21): 3265.

https://doi.org/10.1182/blood.V120.21.3265.3265

Published: 2012

Journal Articles

Iron Trafficking and Distribution in Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia with Sickle Cell Disease and Thalassemia

John B. Porter, MD, Patrick B Walter, PhD, Lynne D Neumayr, MD, Patricia Evans, PhD, Marcela G Weyhmiller, PhD, Paul Harmatz, MD, John C Wood, MD, Ph.D, Jeffery L. Miller, Guenter Weiss, MD, Qing Yuan, Zhiyue J Wang, Regine Grosse, MD, Bjoern P Schoennagel, Joerg Meerpohl, Roland Fischer, PhD, Elliott Vichinsky, MD

Blood (2012) 120 (21): 995.

https://doi.org/10.1182/blood.V120.21.995.995

Published: 2012

Journal Articles

Combined Chelation Therapy with Deferasirox and Deferoxamine In Transfusion-Dependent Thalassemia

Ashutosh Lal, MD, Nancy Sweeters, PNP, Vivian Ng, Drucilla Foote, PNP, Patricia Evans, PhD, Lynne Neumayr, MD, Gregory Kurio, MD, Paul Harmatz, MD, John B. Porter, MD, Elliott Vichinsky, MD

Blood (2010) 116 (21): 4269.

https://doi.org/10.1182/blood.V116.21.4269.4269

Published: 2010

Journal Articles

Increased Nucleosomal DNA Fragmentation in Leukocytes of Thalassemia Patients.

Patrick B Walter, PhD, John B Porter, MD, Patricia Evans, PhD, Janet Kwiatkowski, MD, Ellis J. Neufeld, MD, PhD, Thomas D. Coates, MD, Patricia Giardina, MD, Robert jW Grady, PhD, Elliott Vichinsky, MD, Nancy F. Olivieri, MD, Felicia Trachtenberg, PhD, Daniele Alberti, MD, Ellen Fung, PhD, Bruce Ames, PhD, Annie Lui, BS, Paul Harmatz, MD

Blood (2008) 112 (11): 1868.

https://doi.org/10.1182/blood.V112.11.1868.1868

Published: 2008

Journal Articles

Leukocyte Apoptosis and Mitochondrial Dysfunction in β-Thalassemia Patients Treated with Deferasirox or Deferoxamine.

Patrick B. Walter, PhD, John Porter, MD, Patricia Evans, PhD, Janet L. Kwiatkowski, MD, Ellis J. Neufeld, MD, Thomas Coates, MD, Patricia J. Giardina, MD, Robert W. Grady, PhD, Elliott Vichinsky, MD, Nancy F. Olivieri, MD, Felicia Trachtenberg, PhD, Daniele Alberti, MD, Jaymes Holland, PhD, Ellen Fung, PhD, Bruce Ames, PhD, Annie Lui, BS, Paul Harmatz, MD

Blood (2007) 110 (11): 2773.

https://doi.org/10.1182/blood.V110.11.2773.2773

Published: 2007

Journal Articles

Leukocyte Apoptosis and Inflammation in Iron-Overloaded Patients with Sickle Cell Disease or β-Thalassemia: A Mechanism for Increased Stroke and Disease Severity in Sickle Cell Disease.

Patrick B. Walter, PhD, David W. Killilea, PhD, Ellen B. Fung, PhD, Annie Lui, BS, Jacqueline Madden, PNP, John Porter, MD, Patricia Evans, PhD, Bruce N. Ames, PhD, Elliott Vichinsky, MD, Paul Harmatz, MD

Blood (2006) 108 (11): 1233.

https://doi.org/10.1182/blood.V108.11.1233.1233

Published: 2006

Journal Articles

Control of Oxidant-Stress and Inflammation by Iron Chelators Deferasirox (ICL670) or Deferoxamine in β-Thalassemia: An Ancillary Study of the Novartis CICL670A0107 Trial.

Patrick Walter, PhD, Eric Macklin, PhD, John Porter, MD, Patricia Evans, PhD, Tom Coates, MD, Nancy F. Olivieri, MD, Patricia Giardina, MD, Janet Kwiatkowski, MD, Ellis Neufeld, MD, Bruce Ames, PhD, Jaymes Holland, Peter Marks, MD, Elliott Vichinsky, MD, Paul Harmatz, MD

Blood (2005) 106 (11): 3598.

https://doi.org/10.1182/blood.V106.11.3598.3598

Published: 2005

Journal Articles

Toxic Unbound Iron and Membrane Injury in b-Thalassemia and Sickle Cell Disease: Elevated Non-Transferrin Bound Iron (NTBI) and Malondialdehyde (MDA).

Patrick B. Walter, PhD, Ellen Fung, PhD, David W. Killilea, PhD, Qing Jiang, PhD, Bruce N. Ames, PhD, Jacqueline Madden, PNP, Ellen Butensky, PhD, John Porter, MD, Patricia Evans, PhD, Paul Harmatz, MD, Elliott P. Vichinsky, MD

Blood (2004) 104 (11): 3608.

https://doi.org/10.1182/blood.V104.11.3608.3608

Published: 2004

NARROW

GDF15 and Erythroferrone Mark Erythropoietic Response to ACE-011 (Sotatercept) in Thalassemia

Iron Level and Monocyte Morphology Predict TLR4 Expression and Reactive Oxygen Species Production Which Influences Chronic Inflammation in β-Thalassemia

Residual Erythropoiesis Protects Against Cardiac Iron Loading in Transfusion Dependent Thalassaemia (TDT) By Lowering Labile Plasma Iron (LPI) through Transient Apotransferrin Generation

Association Of Cardiac Iron By T2* With Innate Immune Markers In Transfusion-Dependent Thalassemia Patients Undergoing Combined Chelation Therapy

Determinants Of Tissue Iron Loading In Transfused and Non-Transfused β-Thalassemia and Sickle Cell Disease Patients – Biomarkers Of Iron Regulation and Inflammation

Inflammatory and Vitamin Bio-Markers Of Iron Trafficking and Distribution In Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia With Sickle Cell Disease and Thalassemia (MCSIO PILOT Study)

Innate Immune Cell Expression of Pattern Recognition Receptors From β-Thalassemia Patients During Intensive Combination Chelation Therapy

Metabolomic Biomarkers As Predictors of Iron Load and Oxidative Damage in Iron Overloaded Thalassemia Patients

Iron Trafficking and Distribution in Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia with Sickle Cell Disease and Thalassemia

Combined Chelation Therapy with Deferasirox and Deferoxamine In Transfusion-Dependent Thalassemia

Increased Nucleosomal DNA Fragmentation in Leukocytes of Thalassemia Patients.

Leukocyte Apoptosis and Mitochondrial Dysfunction in β-Thalassemia Patients Treated with Deferasirox or Deferoxamine.

Leukocyte Apoptosis and Inflammation in Iron-Overloaded Patients with Sickle Cell Disease or β-Thalassemia: A Mechanism for Increased Stroke and Disease Severity in Sickle Cell Disease.

Control of Oxidant-Stress and Inflammation by Iron Chelators Deferasirox (ICL670) or Deferoxamine in β-Thalassemia: An Ancillary Study of the Novartis CICL670A0107 Trial.

Toxic Unbound Iron and Membrane Injury in b-Thalassemia and Sickle Cell Disease: Elevated Non-Transferrin Bound Iron (NTBI) and Malondialdehyde (MDA).

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American Society of Hematology

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American Society of Hematology

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