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Journal Articles

Daratumumab (DARA) in Combination with Carfilzomib, Lenalidomide, and Dexamethasone (KRd) in Patients with Newly Diagnosed Multiple Myeloma (MMY1001): Updated Results from an Open-Label, Phase 1b Study

Ajai Chari, Saad Z Usmani, MD, Amrita Krishnan, MD, Sagar Lonial, MD, Raymond Comenzo, Kaida Wu, Jianping Wang, Parul Doshi, Brendan M Weiss, MD, Jordan Schecter, Andrzej J. Jakubowiak, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3110.
https://doi.org/10.1182/blood.V130.Suppl_1.3110.3110
Published: 2017
Journal Articles

Daratumumab in Combination with Carfilzomib and Dexamethasone in Patients (pts) with Relapsed Multiple Myeloma (MMY1001): An Open-Label, Phase 1b Study

Sagar Lonial, MD, Jesus F. San-Miguel, MD, Joaquín Martínez-Lopez, Maria-Victoria Mateos, MD, Joan Blade, Lotfi Benboubker, MD, Albert Oriol, MD, Bertrand Arnulf, Ajai Chari, Luis Pineiro, Kaida Wu, Jianping Wang, Parul Doshi, Jordan Schecter, Philippe Moreau, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1869.
https://doi.org/10.1182/blood.V130.Suppl_1.1869.1869
Published: 2017
Journal Articles

International Validation of a Dithiothreitol (DTT)-Based Method to Resolve the Daratumumab Interference with Blood Compatibility Testing

Claudia I Chapuy, MD, Maria D Aguad, MT(ASCP), Rachel T Nicholson, MLS(ASCP)CM, James P AuBuchon, MD, Claudia S Cohn, MD PhD, Meghan Delaney, DO, MPH, Joan Cid, MD PhD, Walter Dzik, MD, Mark K. Fung, MD PhD, Andreas Greinacher, MD, Ai Leen Ang, MD, Dana V. Devine, PhD, Nancy M Dunbar, MD, Henk Garritsen, MD, Lawrence T Goodnough, MD, Ross Herron, MD, Tor A. Hervig, MD PhD, C. Michael Knudson, MDPhD, Jose M Kutner, MD PhD, Frank Nizzi, DO, Suchitra Pandey, MD, Benjamin Rioux-Masse, MD FRCPC, Kathleen Selleng, MD, Joseph Sweeney, MD, Minoko Takanashi, MD PhD, Aaron A.R. Tobian, MD PhD, Lorna Wall, MSc, Silvano Wendel, MD PhD, David A Westerman, Meredith Unger, PhD MBA, Parul Doshi, Michael F. Murphy, MD FRCP, FRCPath, Larry J. Dumont, PhD MBA, Richard M. Kaufman, MD, The BEST Collaborative
Journal: Blood
Blood (2015) 126 (23): 3567.
https://doi.org/10.1182/blood.V126.23.3567.3567
Published: 2015
Journal Articles

Outcomes and Management of Red Blood Cell Transfusions in Multiple Myeloma Patients Treated with Daratumumab

Ajai Chari, MD, Toshihisa Satta, Amit Tayal, Sundar Jagannath, MD, Hearn Jay Cho, MD PhD, Samir Parekh, MD, Kenneth Lau, Gillian Morgan, Donna Catamero, Juliet Escalon, Erika Florendo, Daniel Verina, Parul Doshi, Huaibao Feng, Clarissa Uhlar, Imran Khan, Tahamtan Ahmadi, Peter M. Voorhees, Maria-Victoria Mateos, Suzanne Arinsburg
Journal: Blood
Blood (2015) 126 (23): 3571.
https://doi.org/10.1182/blood.V126.23.3571.3571
Published: 2015
Journal Articles

Anti-Leukemic Activity of Daratumumab in Acute Myeloid Leukemia Cells and Patient-Derived Xenografts

Cedric Dos Santos, PhD, Shan Xiaochuan, MDPhD, Zhou Chenghui, Georges Habineza Ndikuyeze, Joshua Glover, Tony Secreto, Parul Doshi, PhD, Kate Sasser, Gwenn Danet-Desnoyers, PhD
Journal: Blood
Blood (2014) 124 (21): 2312.
https://doi.org/10.1182/blood.V124.21.2312.2312
Published: 2014
Journal Articles

Modulation of CD38 Expression Levels on Multiple Myeloma Tumor Cells By All- Trans Retinoic Acid Improves the Efficacy of the Anti-CD38 Monoclonal Antibody Daratumumab

Inger S. Nijhof, MD, Henk M. Lokhorst, MDPhD, Berris van Kessel, Richard W.J. Groen, PhD, Anton C. Martens, PhD, Parul Doshi, PhD, Saskia K. Klein, MDPhD, Tuna Mutis, MDPhD, Kate Sasser, Niels W.C.J. van de Donk, MDPhD
Journal: Blood
Blood (2014) 124 (21): 2096.
https://doi.org/10.1182/blood.V124.21.2096.2096
Published: 2014
Journal Articles

Direct in Vitro Comparison of Daratumumab with Surrogate Analogs of CD38 Antibodies MOR03087, SAR650984 and Ab79

Jeroen Lammerts van Bueren, PhD, Danielle Jakobs, Niels Kaldenhoven, Marcel Roza, Sanne Hiddingh, Joyce Meesters, Marleen Voorhorst, Elke Gresnigt, Luus Wiegman, Antonio Ortiz Buijsse, Grietje Andringa, Marije B. Overdijk, PhD, Parul Doshi, PhD, Kate Sasser, Michel de Weers, PhD, Paul W.H.I. Parren, PhD
Journal: Blood
Blood (2014) 124 (21): 3474.
https://doi.org/10.1182/blood.V124.21.3474.3474
Published: 2014
Journal Articles

Daratumumab, a Novel Anti-CD38 Monoclonal Antibody Shows Anti-Tumor Activity in CLL and hampers Leukemia-Microenvironment Interactions

Alba Matas-Céspedes, MS, Anna Vidal-Crespo, MS, Vanina Rodriguez, Julio Delgado, MD PhD, Neus Villamor, MD PhD, Gael Roue, PhD, Elías Campo, MD PhD, Dolors Colomer, PhD, Parul Doshi, PhD, Adrian Wiestner, MD PhD, Paul W.H.I. Parren, PhD, Jeroen Lammerts van Bueren, PhD, Patricia Pérez-Galán, PhD
Journal: Blood
Blood (2014) 124 (21): 4680.
https://doi.org/10.1182/blood.V124.21.4680.4680
Published: 2014