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Nobu Akiyama
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Journal Articles

Cefozoplan, Meropenem, or Imipenem-Cilastatin Versus Cefepime As an Empirical Therapy in High Risk Febrile Neutropenic Adult Patients: A Multicenter Prospective Randomized Trial

Takahiko Nakane, MD, PhD, Toshiharu Tamaki, Kazuo Tamura, MD, PhD, Isao Yoshida, MD, Toshihiro Fukushima, MD, PhD, Yoichi Tatsumi, MD, PhD, Yasunori Nakagawa, MD, Kazuo Hatanaka, MD, Tsutomu Takahashi, MD, PhD, Nobu Akiyama, MD, PhD, Mitsune Tanimoto, MD, PhD, Kazuma Ohyashiki, MD, PhD, Akio Urabe, MD, PhD, Tohru Masaoka, MD, PhD, Akihisa Kanamaru, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1037.
https://doi.org/10.1182/blood.V120.21.1037.1037
Published: 2012
Journal Articles

Interleukin-1 Beta Promotes the Expression of Prox-1 and Vascular Endothelial Growth Factor Receptor Type-3 in Adult Human Dermal Fibroblasts

Matsuo Takuji, Ryosuke Shirasaki, MD, Haruko Tashiro, MD, PhD, Yoko Oka, MD, PhD, Tadashi Yamamoto, MD, Nobu Akiyama, MD, PhD, Kazuo Kawasugi, MD, PhD, Naoki Shirafuji, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 4738.
https://doi.org/10.1182/blood.V120.21.4738.4738
Published: 2012
Journal Articles

CD56(+)CD146(+) Cells in Normal Human Bone Marrow-Stroma Proliferated to Form Tumors in severe Combined Immunodeficiency Mice

Ryosuke Shirasaki, MD, Haruko Tashiro, MD, Yoko Oka, MD, PhD, Tadashi Yamamoto, MD, Nobu Akiyama, MD, PhD, Kazuo Kawasugi, MD, PhD, Naoki Shirafuji, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1328.
https://doi.org/10.1182/blood.V118.21.1328.1328
Published: 2011
Journal Articles

Interleukin-1β Promotes the Expression of CD34 and Granulocyte Colony-Stimulating Factor-Receptor in Adult Dermal Fibroblasts

Haruko Tashiro, MD, Ryosuke Shirasaki, MD, Yoko Oka, MD, PhD, Tadashi Yamamoto, MD, Nobu Akiyama, MD, PhD, Kazuo Kawasugi, MD, PhD, Naoki Shirafuji, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 4815.
https://doi.org/10.1182/blood.V118.21.4815.4815
Published: 2011
Journal Articles

Tcf3/Pbx1 Fusion Molecule Induces the Transcription of Prox-1 and Vascular Endothelial Growth Factor Receptor Type-3

Yoko Oka, MD, PhD, Ryosuke Shirasaki, MD, Haruko Tashiro, MD, Tadashi Yamamoto, MD, Nobu Akiyama, MD, PhD, Kazuo Kawasugi, MD, PhD, Naoki Shirafuji, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1487.
https://doi.org/10.1182/blood.V118.21.1487.1487
Published: 2011
Journal Articles

Efficacy of Gemtuzumab Ozogamicin (GO) Monotherapy on Relapsed/Refractory Acute Promyelocytic Leukemia (APL)

Akihiro Takeshita, MD, PhD, Takaaki Ono, MD, PhD, Yumi Kojima, MD, PhD, Taiichi Kyo, MD, Norio Asou, MD, PhD, Hitoshi Suzushima, MD, PhD, Fumiharu Yagasaki, MD, PhD, Tomoya Maeda, MD, PhD, Masaya Okada, MD, PhD, Chiaki Nakaseko, MD, PhD, Hiroyuki Kanbayashi, MD, PhD, Masaki Yamaguchi, MD, PhD, Mitsutoshi Kurosawa, MD, PhD, Kosuke Tsuboi, MD, PhD, Toshiaki Yujiri, MD, Yasuhito Nannya, MD, PhD, Naokuni Uike, MD, PhD, Nobu Akiyama, MD, PhD, Tetsuya Fukuda, MD, PhD, Kaori Karimata, MD, PhD, Hirokazu Okumura, MD, PhD, Tetsuya Eto, MD, Koh Izumiyama, MD, PhD, Akihiro Watanabe, MD, Nobuyuki Aotsuka, MD, PhD, Katsuro Ito, MD, PhD, Keiji Ozaki, MD, PhD, Tomoki Naoe, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1532.
https://doi.org/10.1182/blood.V118.21.1532.1532
Published: 2011
Journal Articles

Chronic Myelogenous Leukemia Cells Contribute to a Bone Marrow-Stroma in In Vivo NOD/SCID Mouse System.

Ryosuke Shirasaki, Haruko Tashiro, Yoko Oka, Toshihiko Sugao, Nobu Akiyama, Kazuo Kawasugi, Naoki Shirafuji
Journal: Blood
Blood (2009) 114 (22): 2191.
https://doi.org/10.1182/blood.V114.22.2191.2191
Published: 2009
Journal Articles

Acute Myelogenous Leukemia Blasts Contribute to a Bone Marrow-Stroma in In Vivo NOD/SCID Mouse System..

Haruko Tashiro, Ryosuke Shirasaki, Yoko Oka, Toshihiko Sugao, Nobu Akiyama, Kazuo Kawasugi, Naoki Shirafuji
Journal: Blood
Blood (2009) 114 (22): 1621.
https://doi.org/10.1182/blood.V114.22.1621.1621
Published: 2009
Journal Articles

VEGF Autocrine System Is Demonstrated in Some of Acute Promyelocytic Leukemia Cases: Relationship to WBC Count at the Disease Onset.

Toshihiko Sugao, Yoko Oka, Haruko Tashiro, Ryosuke Shirasaki, Nobu Akiyama, Kazuo Kawasugi, Naoki Shirafuji
Journal: Blood
Blood (2009) 114 (22): 4127.
https://doi.org/10.1182/blood.V114.22.4127.4127
Published: 2009
Journal Articles

Genomic Modifications Occur during Maturation in Myeloid Cells

Ryosuke Shirasaki, Haruko Tashiro, Nobu Akiyama, Kazuo Kawasugi, Naoki Shirafuji
Journal: Blood
Blood (2008) 112 (11): 4890.
https://doi.org/10.1182/blood.V112.11.4890.4890
Published: 2008
Journal Articles

FLT3 Internal Tandem Duplication Is Associated with High Relapse Rate and Central Nervous System Involvement in Acute Promyelocytic Leukemia

Haruko Tashiro, Yoko Oka, Toshihiko Sugao, Ryosuke Shirasaki, Mitsuho Noguchi-Mizutani, Nobu Akiyama, Kazuo Kawasugi, Naoki Shirafuji
Journal: Blood
Blood (2008) 112 (11): 4849.
https://doi.org/10.1182/blood.V112.11.4849.4849
Published: 2008
Journal Articles

Natural History of 33 Patients with Upshaw-Schulman Syndrome Has Revealed That All the Gravida Develop Thrombocytopenia, Often Followed by Thrombotic Microangiopathy with Stillbirth.

Yoshihiro Fujimura, MD, Masanori Matsumoto, MD, Koichi Kokame, PhD, Hideo Yagi, MD, Ayami Isonishi, PhD, Tomomi Matsuyama, MD, Seiji Kato, PhD, Hiromichi Ishizashi, PhD, Yasuaki Shida, MD, Nishio Kenji, MD, Nobu Akiyama, MD, Junji Tomiyama, MD, Kazuhiro Natori, MD, Yasunobu Kuraishi, MD, Yutaka Imamura, MD, Nobumasa Inoue, MD, Satoshi Higasa, MD, Masako Seike, MD, Teruhiko Kozuka, MD, Masamichi Hara, MD, Mitsuhiko Sugimoto, MD, Hideo Wada, MD, Mitsuru Murata, MD, Toshiyuki Miyata, PhD, Yasuo Ikeda, MD
Journal: Blood
Blood (2007) 110 (11): 3211.
https://doi.org/10.1182/blood.V110.11.3211.3211
Published: 2007
Journal Articles

Upshaw-Schulman Syndrome: A Masqueraded Thrombocytopenia during Pregnancy.

Tomomi Matsuyama, Masanori Matsumoto, Seiji Kato, Nobu Akiyama, Junji Tomiyama, Kazuhiko Natori, Yasunobu Kuraishi, Yutaka Imamura, Nobumasa Inoue, Koichi Kokame, Toshiyuki Miyata, Yoshihiro Fujimura
Journal: Blood
Blood (2005) 106 (11): 2644.
https://doi.org/10.1182/blood.V106.11.2644.2644
Published: 2005
Journal Articles

Vitamin K2 (VK2) Monotherapy and VK2 Plus D3 Combination Therapy in Low-Risk Myelodysplastic Syndrome: A Prospective Japanese Study.

Keisuke Miyazawa, MD, Kazuma Ohyashiki, MD, Nobu Akiyama, MD, Yoshinobu Kanda, MD, Kaoru Tohyama, MD, Mistuhiro Omine, MD, Kinuko Mitani, MD
Journal: Blood
Blood (2005) 106 (11): 2528.
https://doi.org/10.1182/blood.V106.11.2528.2528
Published: 2005