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Journal Articles

Type 2 but Not Type 1 Calreticulin Mutants Exhibit Loss of Chaperone Function Due to C-Terminal Structural Interference, and Bind to Wild Type Calreticulin in a Dominant Negative Manner

Nicole S Arellano, Jacqueline Gomez, Harrison S Greenbaum, Michele Ciboddo, Deborah Rodriguez, Amy K Chen, Lulu Allie, Alex Rosencrance, Shannon Elf

Blood (2022) 140 (Supplement 1): 1087–1088.

https://doi.org/10.1182/blood-2022-166506

Published: 2022

Journal Articles

Myeloproliferative Neoplasm-Associated Type 2 Calreticulin Mutations Differentially Activate and Depend on the ATF6 Pathway of the UPR

Nicole S Arellano, Katarzyna Kurylowicz, Luke Maxwell, Harrison S Greenbaum, Juan Ibarra, Shannon Elf

Blood (2021) 138 (Supplement 1): 3588.

https://doi.org/10.1182/blood-2021-151632

Published: 2021

Journal Articles

Type I Calreticulin Mutations Result in Hyperactivation of Its Acetyltransferase Function and Iron Metabolism, Inducing a Susceptibility to Ferroptosis

Harrison S Greenbaum, Maria Evers, Alex Rosencrance, Luke Maxwell, Katarzyna Kurylowicz, Nicole S Arellano, Michele Ciboddo, Jinjun Gao, Juan Ibarra, Shannon Elf

Blood (2021) 138 (Supplement 1): 3593.

https://doi.org/10.1182/blood-2021-153480

Published: 2021

Journal Articles

Type 1 Calreticulin Mutations Differentially Activate the IRE1α-XBP1 Pathway of the Unfolded Protein Response to Drive Myeloproliferative Neoplasms

Blood (2021) 138 (Supplement 1): 628.

https://doi.org/10.1182/blood-2021-147859

Published: 2021