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Journal Articles

Precocious Differentiation of Somatic and Pluripotent Stem Cells Bearing Pre-Arranged TCR

Nicholas Klemen, MD, Raul Vizcardo, PhD, Linda Tran, BS, Nicholas P. Restifo, MD

Blood (2015) 126 (23): 847.

https://doi.org/10.1182/blood.V126.23.847.847

Published: 2015

Journal Articles

Big bang theory of stem-like T cells confirmed

Nicholas P. Restifo

Blood (2014) 124 (4): 476–477.

https://doi.org/10.1182/blood-2014-06-578989

Published: 2014

Journal Articles

Essentials of Th17 cell commitment and plasticity

Pawel Muranski, Nicholas P. Restifo

Blood (2013) 121 (13): 2402–2414.

https://doi.org/10.1182/blood-2012-09-378653

Published: 2013

Journal Articles

Moving T memory stem cells to the clinic

Luca Gattinoni, Nicholas P. Restifo

Blood (2013) 121 (4): 567–568.

https://doi.org/10.1182/blood-2012-11-468660

Published: 2013

Journal Articles

The power and pitfalls of IL-12

Sid P. Kerkar, Nicholas P. Restifo

Blood (2012) 119 (18): 4096–4097.

https://doi.org/10.1182/blood-2012-03-415018

Published: 2012

Journal Articles

Human effector CD8 + T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy

Christian S. Hinrichs, Zachary A. Borman, Luca Gattinoni, Zhiya Yu, William R. Burns, Jianping Huang, Christopher A. Klebanoff, Laura A. Johnson, Sid P. Kerkar, Shicheng Yang, Pawel Muranski, Douglas C. Palmer, Christopher D. Scott, Richard A. Morgan, Paul F. Robbins, Steven A. Rosenberg, Nicholas P. Restifo

Blood (2011) 117 (3): 808–814.

https://doi.org/10.1182/blood-2010-05-286286

Published: 2011

Includes: Supplemental data

Journal Articles

Improving Adoptive Immunotherapy Using Less-Differentiated T Cells

Nicholas P. Restifo, MD, Madhu Sukumar, Ph.D., Luca Gattinoni, MD

Blood (2010) 116 (21): SCI-49.

https://doi.org/10.1182/blood.V116.21.SCI-49.SCI-49

Published: 2010

Journal Articles

Th17-Derived Memory Cells Are Long-Lived and Retain a Stem-Like Molecular Signature

Pawel Muranski, MD, Zachary Borman, Sid Kerkar, Yun Ji, Luca Gattinoni, MD, Reger N Robert, Luis Sanchez-Perez, Klebanoff A Christopher, Zhiya Yu, Kern J Steven, Gabriela Ferreyra, Robert L Danner, Nicholas P Restifo

Blood (2010) 116 (21): 1018.

https://doi.org/10.1182/blood.V116.21.1018.1018

Published: 2010

Journal Articles

Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells

James N. Kochenderfer, Zhiya Yu, Dorina Frasheri, Nicholas P. Restifo, Steven A. Rosenberg

Blood (2010) 116 (19): 3875–3886.

https://doi.org/10.1182/blood-2010-01-265041

Published: 2010

Includes: Supplemental data

Journal Articles

IL-17A-Expressing CD4+ T Cells Must Acquire the Expression of T-Bet and IFN-γto Destroy Tumor Cells In Vivo.

Pawel Muranski, MD, Sid P Kerkar, Zachary A Borman, Robert Reger, Luis Sanchez-Perez, Christian S Hinrichs, Zhiya Yu, Douglas C Palmer, Luca Gattinoni, Nicholas P. Restifo

Blood (2009) 114 (22): 468.

https://doi.org/10.1182/blood.V114.22.468.468

Published: 2009

Journal Articles

Programming tumor-reactive effector memory CD8 + T cells in vitro obviates the requirement for in vivo vaccination

Christopher A. Klebanoff, Zhiya Yu, Leroy N. Hwang, Douglas C. Palmer, Luca Gattinoni, Nicholas P. Restifo

Blood (2009) 114 (9): 1776–1783.

https://doi.org/10.1182/blood-2008-12-192419

Published: 2009

Includes: Supplemental data

Journal Articles

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

Blood (2009) 114 (3): 535–546.

https://doi.org/10.1182/blood-2009-03-211714

Published: 2009

Journal Articles

Type 17 CD8 + T cells display enhanced antitumor immunity

Christian S. Hinrichs, Andrew Kaiser, Chrystal M. Paulos, Lydie Cassard, Luis Sanchez-Perez, Bianca Heemskerk, Claudia Wrzesinski, Zachary A. Borman, Pawel Muranski, Nicholas P. Restifo

Blood (2009) 114 (3): 596–599.

https://doi.org/10.1182/blood-2009-02-203935

Published: 2009

Journal Articles

Does IL-17 promote tumor growth?

Pawel Muranski, Nicholas P. Restifo

Blood (2009) 114 (2): 231–232.

https://doi.org/10.1182/blood-2009-04-215541

Published: 2009

Journal Articles

Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers

Andrea Boni, Pawel Muranski, Lydie Cassard, Claudia Wrzesinski, Chrystal M. Paulos, Douglas C. Palmer, Luca Gattinoni, Christian S. Hinrichs, Chi-Chao Chan, Steven A. Rosenberg, Nicholas P. Restifo

Blood (2008) 112 (12): 4746–4754.

https://doi.org/10.1182/blood-2008-07-169797

Published: 2008

Includes: Supplemental data

Journal Articles

Treatment of Large Established Murine Melanoma with Th17 Polarized CD4+ T Helper Cells Genetically Engineered to Express MHC Class IIRestricted T Cell Receptor

Pawel Muranski, MD, Christian S. Hinrichs, Luis Sanchez-Perez, Andrea Boni, Sid Kerkar, Luca Gattinoni, Zhia Yu, Nicholas P. Restifo

Blood (2008) 112 (11): 3911.

https://doi.org/10.1182/blood.V112.11.3911.3911

Published: 2008

Journal Articles

Tumor-specific Th17-polarized cells eradicate large established melanoma

Pawel Muranski, Andrea Boni, Paul A. Antony, Lydie Cassard, Kari R. Irvine, Andrew Kaiser, Chrystal M. Paulos, Douglas C. Palmer, Christopher E. Touloukian, Krzysztof Ptak, Luca Gattinoni, Claudia Wrzesinski, Christian S. Hinrichs, Keith W. Kerstann, Lionel Feigenbaum, Chi-Chao Chan, Nicholas P. Restifo

Blood (2008) 112 (2): 362–373.

https://doi.org/10.1182/blood-2007-11-120998

Published: 2008

Includes: Supplemental data

Journal Articles

IL-2 and IL-21 confer opposing differentiation programs to CD8 + T cells for adoptive immunotherapy

Christian S. Hinrichs, Rosanne Spolski, Chrystal M. Paulos, Luca Gattinoni, Keith W. Kerstann, Douglas C. Palmer, Christopher A. Klebanoff, Steven A. Rosenberg, Warren J. Leonard, Nicholas P. Restifo

Blood (2008) 111 (11): 5326–5333.

https://doi.org/10.1182/blood-2007-09-113050

Published: 2008

Includes: Supplemental data

Journal Articles

Immunologic ignorance of vascular endothelial cells expressing minor histocompatibility antigen

Beatrice Bolinger, Philippe Krebs, Yinghua Tian, Daniel Engeler, Elke Scandella, Simone Miller, Douglas C. Palmer, Nicholas P. Restifo, Pierre-Alain Clavien, Burkhard Ludewig

Blood (2008) 111 (9): 4588–4595.

https://doi.org/10.1182/blood-2007-09-114769

Published: 2008

Includes: Supplemental data

Journal Articles

CTLA-4 dysregulation of self/tumor-reactive CD8 + T-cell function is CD4 + T-cell dependent

Luca Gattinoni, Anju Ranganathan, Deborah R. Surman, Douglas C. Palmer, Paul A. Antony, Marc R. Theoret, David M. Heimann, Steven A. Rosenberg, Nicholas P. Restifo

Blood (2006) 108 (12): 3818–3823.

https://doi.org/10.1182/blood-2006-07-034066

Published: 2006

NARROW

Precocious Differentiation of Somatic and Pluripotent Stem Cells Bearing Pre-Arranged TCR

Big bang theory of stem-like T cells confirmed

Essentials of Th17 cell commitment and plasticity

Moving T memory stem cells to the clinic

The power and pitfalls of IL-12

Human effector CD8 + T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy

Improving Adoptive Immunotherapy Using Less-Differentiated T Cells

Th17-Derived Memory Cells Are Long-Lived and Retain a Stem-Like Molecular Signature

Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells

IL-17A-Expressing CD4+ T Cells Must Acquire the Expression of T-Bet and IFN-γto Destroy Tumor Cells In Vivo.

Programming tumor-reactive effector memory CD8 + T cells in vitro obviates the requirement for in vivo vaccination

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

Type 17 CD8 + T cells display enhanced antitumor immunity

Does IL-17 promote tumor growth?

Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers

Treatment of Large Established Murine Melanoma with Th17 Polarized CD4+ T Helper Cells Genetically Engineered to Express MHC Class IIRestricted T Cell Receptor

Tumor-specific Th17-polarized cells eradicate large established melanoma

IL-2 and IL-21 confer opposing differentiation programs to CD8 + T cells for adoptive immunotherapy

Immunologic ignorance of vascular endothelial cells expressing minor histocompatibility antigen

CTLA-4 dysregulation of self/tumor-reactive CD8 + T-cell function is CD4 + T-cell dependent

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American Society of Hematology

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American Society of Hematology

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