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Journal Articles

An Open-Label, Multi-Center Phase 2 Study to Assess the Safety and Efficacy of Burixafor (GPC-100) and Propranolol with G-CSF for the Mobilization of Stem Cells in Patients with Multiple Myeloma Undergoing Autologous Stem Cell Transplant

Nina Caculitan, GaYeon Kim, Ann Woolfrey, Luke P. Akard, Ah-Reum Jeong, Jack Khouri, Gunjan L. Shah, Pina M. Cardarelli
Journal: Blood
Blood (2024) 144 (Supplement 1): 4858.
https://doi.org/10.1182/blood-2024-208805
Published: 2024
Journal Articles

Combined CXCR-4 Inhibition with Novel Agent GPC-100 (burixafor) and Beta 2 Adrenergic Receptor Blockade Enhances Cytarabine Response for Acute Myeloid Leukemia Blasts on Stroma

Yueming Tang, Adam Braun, Zachary von Behren, Jieya Wu, Caitlyn Haley, Chunxiao Zhang, Brenda Loera, Pina M. Cardarelli, Nina Caculitan, Sylvia Chien, Jin Dai, Vivian G. Oehler, Jianying Zhang, Guido Marcucci, Pamela S. Becker
Journal: Blood
Blood (2024) 144 (Supplement 1): 2758.
https://doi.org/10.1182/blood-2024-210120
Published: 2024
Journal Articles

Strategy to Improve Functional T-Cell Yield in Peripheral Blood By Co-Inhibition of Beta-2 Adrenergic and CXCR4 Signaling Pathways

Devki D. Sukhtankar, Thomas Cayton, Ashley Chin, Christian Ramos, Kanchan G Jhaver, Nina Caculitan, Pina M. Cardarelli
Journal: Blood
Blood (2024) 144 (Supplement 1): 4852.
https://doi.org/10.1182/blood-2024-204101
Published: 2024
Journal Articles

Trial in Progress: An Open-Label, Multi-Center Phase 2 Study to Assess the Safety and Efficacy of Burixafor (GPC-100) and Propranolol with and without G-CSF for the Mobilization of Stem Cells in Patients with Multiple Myeloma Undergoing Autologous Stem Cell Transplant

Nina Caculitan, Josephine M. Cardarelli, Jack Khouri, Hyung C Suh, Muthalagu Ramanathan, Ann Woolfrey
Journal: Blood
Blood (2023) 142 (Supplement 1): 7082.
https://doi.org/10.1182/blood-2023-187191
Published: 2023
Journal Articles

Combination of Propranolol and a Novel CXCR4 Antagonist Burixafor (GPC-100) for Enhanced Hematopoietic Cell Mobilization

Devki D. Sukhtankar, Thomas Cayton, Piotr Zalicki, Junhee Choi, Seonggyeong Mun, Yoonjung Jo, Sujeong Kim, Ji Yeong Lee, Mi-Na Kim, Ashley Chin, Christian Ramos, Won-Ki Huh, Sohui Kim, Nina Caculitan, Jae-Yeon Jeong, Josephine M. Cardarelli
Journal: Blood
Blood (2023) 142 (Supplement 1): 3428.
https://doi.org/10.1182/blood-2023-182226
Published: 2023
Journal Articles

GPC-100 Is a Novel CXCR4 Inhibitor That Leads to Improved in Vitro Potency and In Vivo Efficacy in Stem Cell Mobilization When Combined with a Beta-Blocker

Juan Jose Fung, Valerie Chiou, Jaemin Lee, Yongdae Jang, Junhee Choi, Piotr Zalicki, Thomas Cayton, Ashley Chin, Niña Caculitan, SoHui Kim, Jiyeong Lee, Devki Sukhtankar, Eunhee Kim, Josephine Cardarelli
Journal: Blood
Blood (2022) 140 (Supplement 1): 4489–4490.
https://doi.org/10.1182/blood-2022-160248
Published: 2022