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Neil Maclean, BSc
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Journal Articles

Ibrutinib Sensitizes AML Cells to ROS Inducers Via a BTK-Independent Mechanism

Lianne E Rotin, BHSc, Marcela Gronda, MSc, Neil Maclean, BSc, Feng-Hsu Lin, PhD, Jeff Wrana, PhD, Alessandro Datti, PhD, Dwayne L Barber, PhD, Michael F Moran, PhD, Mark D Minden, MDPhD, Malik Slassi, PhD, Aaron D Schimmer, MDPhD
Journal: Blood
Blood (2014) 124 (21): 2226.
https://doi.org/10.1182/blood.V124.21.2226.2226
Published: 2014
Journal Articles

Targeting The Mitochondrial ClpP As a Novel Therapeutic Strategy For Acute Myeloid Leukemia

Alicia Cole, PhD, Zezhou Wang, PhD, Rachel Mattson, Etienne Coyaud, PhD, Rose Hurren, Marcela Gronda, MSc, Fengshu Lin, PhD, Neil Maclean, BSc, Elisa Leung, BSc, Yihua Qiu, MD, Nianxiang Zhang, PhD, Kevin R. Coombes, PhD, Mark D. Minden, MD PhD, Walid A. Houry, PhD, Zenyaho Hao, PhD, Steven M. Kornblau, MD, Brian Raught, PhD, Aaron Schimmer, PhD, MD
Journal: Blood
Blood (2013) 122 (21): 3937.
https://doi.org/10.1182/blood.V122.21.3937.3937
Published: 2013
Journal Articles

Mutations In UBA3 Confer Resistance To The NEDD8-Activating Enzyme Inhibitor MLN4924 In Human Leukemic Cells

G. Wei Xu, MD, PhD, Julia I. Toth, PhD, Sara R. da Silva, BSc, Stacey-Lynn Paiva, BSc, Julie L. Lukkarila, PhD, Rose Hurren, Neil Maclean, BSc, Mahadeo A. Sukhai, PhD, Rabindra N. Bhattacharjee, PhD, Carolyn A. Goard, PhD, Bruno C Medeiros, MD, Patrick T. Gunning, PhD, Sirano Dhe-Paganon, PhD, Matthew D. Petroski, PhD, Aaron Schimmer, PhD, MD
Journal: Blood
Blood (2013) 122 (21): 2527.
https://doi.org/10.1182/blood.V122.21.2527.2527
Published: 2013
Journal Articles

Targeting the Mammalian Mitochondrial Clpp (mClpP) As a Novel Therapeutic Strategy for Acute Myeloid Leukemia

Alicia Cole, PhD, Zezhou Wang, PhD, Rachel Mattson, Rose Hurren, BSc, Fengshu Lin, PhD, Marcela Gronda, MSc, Neil Maclean, BSc, Methvin Isaac, PhD, Elisa Leung, BSc., Mohan Babu, PhD, Mahadeo A. Sukhai, PhD, Walid A. Houry, PhD, Aaron D. Schimmer, MD
Journal: Blood
Blood (2012) 120 (21): 3603.
https://doi.org/10.1182/blood.V120.21.3603.3603
Published: 2012
Journal Articles

AML Cells Have Altered Mitochondrial Biogenesis and Low Spare Reserve Capacity in Their Respiratory Chain That Renders Them Susceptible to Oxidative Metabolic Stress.

Shrivani Sriskanthadevan, PhD, Timothy E Chung, Marko Skrtic, PhD, Bozhena Jhas, BSc, Rose Hurren, BSc, Marcela Gronda, MSc, Xiao Ming Wang, Yulia Jitkova, PhD, Mahadeo A. Sukhai, PhD, Feng-Hsu Lin, PhD, Neil Maclean, BSc, Rob C. Laister, PhD, Peter Mullen, PhD, Stephanie Xie, Linda Penn, PhD, Ian M. Rogers, PhD, John E. Dick, PhD $, Mark D. Minden, MD, PhD, Aaron D Schimmer, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2581.
https://doi.org/10.1182/blood.V120.21.2581.2581
Published: 2012
Journal Articles

Inhibition of Mitochondrial Translation As a Therapeutic Strategy for Acute Myeloid Leukemia (AML)

Marko Skrtic, BSc, Shrivani Sriskanthadevan, PhD, Bozhena Livak, BSc, Marinella Gebbia, PhD, Xiaoming Wang, Zezhou Wang, PhD, Rose Hurren, BSc, Yulia Jitkova, PhD, Marcela Gronda, MSc, Neil Maclean, BSc, Courteney Lai, BSc, Yanina Eberhard, BSc, PhD, Justyna Bartoszko, BSc, Paul A. Spagnuolo, PhD, Angela Rutledge, PhD, Alessandro Datti, PhD, Troy Ketela, Jason Moffat, Brian H Robinson, PhD, Jessie M Cameron, PhD, Jeff L. Wrana, PhD, Connie J. Eaves, PhD, Mark D. Minden, MD, PhD, Jean C.Y. Wang, MD, PhD, John E. Dick, PhD, R. Keith Humphries, MD, PhD, Corey Nislow, PhD, Guri Giaever, PhD, Aaron D Schimmer, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 233.
https://doi.org/10.1182/blood.V118.21.233.233
Published: 2011