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Journal Articles

Immunoglobulin Heavy Chain (IgH) Knockout Inhibits Proliferation of Pre-BCR + B-Cell Acute Lymphoblastic Leukemia (B-ALL) Via a FOXO1 and MYC Dependent Mechanism

Stefan Koehrer, MD, Ondrej Havranek, MDPhD, R Eric Davis, MD, Felix Seyfried, MD, Greg Coffey, PhD, Ekaterina Kim, MS, Nathalie Y. Rosin, PhD, Elisa ten Hacken, PhD, Ulrich Jäger, MD, Katrina Vanura, PhD, Susan O'Brien, MD, Deborah A. Thomas, MD, Hagop M. Kantarjian, MD, Dipanjan Ghosh, PhD, Zhiqiang Wang, Lüder Hinrich Meyer, MD, Hassan Jumaa, PhD, Jan A. Burger, MDPhD

Blood (2014) 124 (21): 287.

https://doi.org/10.1182/blood.V124.21.287.287

Published: 2014

Journal Articles

Bruton′s Tyrosine Kinase Inhibitor Ibrutinib Interferes With Constitutive and Induced Pre-B Cell Receptor Signaling In B-Cell Acute Lymphoblastic Leukemia

Ekaterina Kim, MS, Stefan Koehrer, MD, Nathalie Y. Rosin, PhD, Zhiqiang Wang, Ph.D., Deborah A. Thomas, MD, Farhad Ravandi, MD, Steven M. Kornblau, MD, Hagop M. Kantarjian, MD, Susan O'Brien, MD, Zeev Estrov, MD, Joseph J. Buggy, PhD, Markus Muschen, MD, PhD, Richard E. Davis, MD, Jan A. Burger, MD, PhD

Blood (2013) 122 (21): 1399.

https://doi.org/10.1182/blood.V122.21.1399.1399

Published: 2013

Journal Articles

The PI3K Delta Inhibitor Idelalisib Interferes With Pre-B Cell Receptor Signaling In Acute Lymphoblastic Leukemia (ALL): A New Therapeutic Concept

Nathalie Y. Rosin, PhD, Ekaterina Kim, MS, Stefan Koehrer, MD, Zhiqiang Wang, Ph.D., Susan O'Brien, MD, William G. Wierda, MD, Deborah A. Thomas, MD, Zeev Estrov, MD, Hagop M. Kantarjian, MD, Brian Lannutti, PhD, Richard E. Davis, PhD, Jan A. Burger, MD, PhD

Blood (2013) 122 (21): 2632.

https://doi.org/10.1182/blood.V122.21.2632.2632

Published: 2013

Journal Articles

Inhibition Of PI3K-δ and -γ Isoforms By IPI-145 In Chronic Lymphocytic Leukemia Overcomes Signals From PI3K/AKT/S6 Pathway and Promotes Apoptosis

Kumudha Balakrishnan, Marisa Peluso, Min Fu, Nathalie Y. Rosin, PhD, Jan A. Burger, MD, PhD, William G. Wierda, MD, PhD, Michael J. Keating, MD, Kerrie Faia, MS, Susan O'Brien, MD, Jeff Kutok, Karen McGovern, PhD, Varsha Gandhi, PhD

Blood (2013) 122 (21): 4167.

https://doi.org/10.1182/blood.V122.21.4167.4167

Published: 2013

Journal Articles

Pre-BCR Signaling Activity Predicts Sensitivity To Syk Kinase Inhibition In B Cell Acute Lymphoblastic Leukemia (B-ALL)

Stefan Koehrer, MD, Richard E. Davis, M.D., Greg Coffey, PhD, Ekaterina Kim, MS, Nathalie Y. Rosin, PhD, Elisa ten Hacken, Susan O'Brien, MD, William G. Wierda, MD, PhD, Zeev Estrov, MD, Deborah A. Thomas, MD, Hagop M. Kantarjian, MD, Zhiqiang Wang, Ph.D., Hassan Jumaa, PhD, Jan A. Burger, MD, PhD

Blood (2013) 122 (21): 614.

https://doi.org/10.1182/blood.V122.21.614.614

Published: 2013

Journal Articles

Efficacy of PRT060318, a Novel Highly Specific SYK Inhibitor, in Acute Lymphoblastic Leukemia (ALL)

Stefan KÖhrer, MD, Greg Coffey, PhD, Ekaterina Kim, MS, Nathalie Y Rosin, PhD, Uma Sinha, PhD, Anjali Pandey, PhD, Medhat Shehata, Ulrich Jäger, Susan M. O'Brien, MD, William G. Wierda, MD, Ph.D., Zeev Estrov, MD, PhD, Deborah Thomas, MD, Hagop M Kantarjian, Jan A. Burger, MD, PhD

Blood (2012) 120 (21): 3532.

https://doi.org/10.1182/blood.V120.21.3532.3532

Published: 2012

Journal Articles

In Vitro Effects of PI3Kδ Inhibitor GS-1101 (Cal-101) in Acute Lymphoblastic Leukemia (ALL)

Nathalie Y Rosin, PhD, Stefan Koehrer, MD, Ekaterina Kim, MS, Susan O'Brien, M.D., William G. Wierda, MD, Ph.D., Deborah A. Thomas, MD, Zeev Estrov, MD, PhD, Hagop M. Kantarjian, MD, Brian J. Lannutti, PhD, Jan A. Burger, MD, PhD

Blood (2012) 120 (21): 3534.

https://doi.org/10.1182/blood.V120.21.3534.3534

Published: 2012

Journal Articles

Activity of Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib (PCI-32765) in B-Cell Acute Lymphoblastic Leukemia (B-ALL).

Ekaterina Kim, MS, Stefan Koehrer, MD, Nathalie Y Rosin, PhD, Deborah A. Thomas, MD, Farhad Ravandi, MD, Steven M. Kornblau, MD, PhD, Hagop M. Kantarjian, MD, Susan O'Brien, MD, Zeev Estrov, MD, PhD, Joseph J. Buggy, PhD, Jan A. Burger, MD, PhD

Blood (2012) 120 (21): 2569.

https://doi.org/10.1182/blood.V120.21.2569.2569

Published: 2012

NARROW

Immunoglobulin Heavy Chain (IgH) Knockout Inhibits Proliferation of Pre-BCR + B-Cell Acute Lymphoblastic Leukemia (B-ALL) Via a FOXO1 and MYC Dependent Mechanism

Bruton′s Tyrosine Kinase Inhibitor Ibrutinib Interferes With Constitutive and Induced Pre-B Cell Receptor Signaling In B-Cell Acute Lymphoblastic Leukemia

The PI3K Delta Inhibitor Idelalisib Interferes With Pre-B Cell Receptor Signaling In Acute Lymphoblastic Leukemia (ALL): A New Therapeutic Concept

Inhibition Of PI3K-δ and -γ Isoforms By IPI-145 In Chronic Lymphocytic Leukemia Overcomes Signals From PI3K/AKT/S6 Pathway and Promotes Apoptosis

Pre-BCR Signaling Activity Predicts Sensitivity To Syk Kinase Inhibition In B Cell Acute Lymphoblastic Leukemia (B-ALL)

Efficacy of PRT060318, a Novel Highly Specific SYK Inhibitor, in Acute Lymphoblastic Leukemia (ALL)

In Vitro Effects of PI3Kδ Inhibitor GS-1101 (Cal-101) in Acute Lymphoblastic Leukemia (ALL)

Activity of Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib (PCI-32765) in B-Cell Acute Lymphoblastic Leukemia (B-ALL).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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