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Nataliya Kuptsova
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Journal Articles

Sustained efficacy of zanubrutinib (zanu) vs bendamustine + rituximab (BR) in treatment (tx)-naive chronic lymphocytic leukemia/small lymphocytic lymphoma (TN SLL/CLL) and continued favorable survival in non-randomized patients (pts) with del(17p): 6-year follow-up in the phase 3 SEQUOIA study

Free
Constantine Tam, Talha Munir, Tadeusz Robak, Jennifer Brown, Brad Kahl, Paolo Ghia, Stephen Opat, Patricia Walker, Masa Lasica, Ian Flinn, Jiayi Shen, Nataliya Kuptsova-Clarkson, Marcus Lefebure, Jamie Hirata, Wojciech Jurczak, Mazyar Shadman
Journal: Blood
Blood (2025) 146 (Supplement 1): 2129.
https://doi.org/10.1182/blood-2025-2129
Published: 2025
Journal Articles

Long-term results of patients receiving zanubrutinib in the phase 3 ALPINE study confirm sustained benefit of zanubrutinib in patients with relapsed/refractory chronic lymphocytic leukemia or small lymphocytic lymphoma (R/R CLL/SLL): Up to 6 years of follow-up with the long-term extension (LTE1)

Free
Constantine Tam, Andrzej Mital, Robert Weinkove, Wojciech Jurczak, Xin Yan, Nataliya Kuptsova-Clarkson, Tian Tian, Megan Wang, Jamie Hirata
Journal: Blood
Blood (2025) 146 (Supplement 1): 2123.
https://doi.org/10.1182/blood-2025-2123
Published: 2025
Journal Articles

Zanubrutinib + venetoclax for treatment-naive chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), including patients with del(17p) and/or TP53 mutation and unmutated immunoglobulin heavy-chain variable status: 3-year results from SEQUOIA arm D

Free
Mazyar Shadman, Talha Munir, Shuo Ma, Masa Lasica, Monica Tani, Tadeusz Robak, Ian Flinn, Jennifer R. Brown, Paolo Ghia, Emmanuelle Ferrant, Constantine Tam, Wojciech Janowski, Wojciech Jurczak, Linlin Xu, Tian Tian, Nataliya Kuptsova-Clarkson, Marcus Lefebure, Jamie Hirata, Alessandra Tedeschi
Journal: Blood
Blood (2025) 146 (Supplement 1): 5669.
https://doi.org/10.1182/blood-2025-5669
Published: 2025
Journal Articles

Characterization of Bruton Tyrosine Kinase Inhibitor (BTKi)-Related Adverse Events in a Head-to-Head Trial of Acalabrutinib Versus Ibrutinib in Previously Treated Chronic Lymphocytic Leukemia (CLL)

Free
John F. Seymour, John C. Byrd, Peter Hillmen, Paolo Ghia, Arnon P. Kater, Asher Chanan-Khan, Richard Furman, Susan M. O'Brien, Jennifer R Brown, Anthony R. Mato, Stephan Stilgenbauer, Nataliya Kuptsova-Clarkson, Paulo Miranda, Dennis Wagner, Kara Higgins, Sophia Sohoni, Wojciech Jurczak
Journal: Blood
Blood (2021) 138 (Supplement 1): 3721.
https://doi.org/10.1182/blood-2021-146228
Published: 2021
Journal Articles

New Acalabrutinib Formulation Enables Co-Administration with Proton Pump Inhibitors and Dosing in Patients Unable to Swallow Capsules (ELEVATE-PLUS)

Free
Shringi Sharma, Xavier Pepin, Harini Burri, Lianqing Zheng, Nataliya Kuptsova-Clarkson, Anouk de Jong, Ting Yu, Holly L MacArthur, Michal Majewski, Joseph A Ware, James Mann, David Ramies, Veerendra Munugalavadla, Louise Sheridan, Helen Tomkinson
Journal: Blood
Blood (2021) 138 (Supplement 1): 4365.
https://doi.org/10.1182/blood-2021-146610
Published: 2021
Journal Articles

Pooled Analysis of Cardiovascular Events from Clinical Trials Evaluating Acalabrutinib Monotherapy in Patients with Chronic Lymphocytic Leukemia (CLL)

Free
Jennifer R Brown, MD PhD, John C. Byrd, MD, Paolo Ghia, MD PhD, Jeff P Sharman, MD, Peter Hillmen, MBChB, PhD FRCP, FRCPath, Deborah M. Stephens, DO, Clare Sun, MD, Wojciech Jurczak, John M. Pagel, MDPhD, Alessandra Ferrajoli, MD, Priti Patel, MD, Marshall Baek, Tamara Lezhava, Nataliya Kuptsova-Clarkson, MD, Javid J. Moslehi, MD, Richard R. Furman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 52–54.
https://doi.org/10.1182/blood-2020-134797
Published: 2020
Journal Articles

Moxetumomab Pasudotox-Tdfk in Heavily Pretreated Patients with Relapsed/Refractory Hairy Cell Leukemia (HCL): Long-Term Follow-up from the Pivotal Phase 3 Trial

Free
Robert J. Kreitman, MD, Claire E. Dearden, MD FRCP, FRCPath, Pier Luigi Luigi Zinzani, MD, Julio Delgado, Tadeusz Robak, MD, Philipp D le Coutre, MD, Bjorn T. Gjertsen, MD PhD, Xavier Troussard, MD, Gail J. Roboz, MD, Lionel Karlin, MD, Douglas E Gladstone, MD, Nataliya Kuptsova-Clarkson, MD, Shiyao Liu, Priti Patel, MD, Wyndham Wilson, MD, Ira Pastan, MD, Francis J. Giles, MD FRCPI, FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 2808.
https://doi.org/10.1182/blood-2019-122307
Published: 2019
Journal Articles

XPD DNA Nucleotide Excision Repair (NER) Gene Polymorphisms Associated with DNA Repair Deficiency May Predict Better Treatment Outcomes in Secondary Acute Myeloid Leukemia (AML).

Free
Nataliya Kuptsova-Clarkson, PhD, Christine Ambrosone, PhD, Joli Weiss, PhD, Maria R. Baer, MD, Lara Sucheston, PhD, Gary Zirpoli, PhD, Kenneth Kopecky, PhD, Laurie Ann Ford, Javier Blanco, PhD, Meir Wetzler, MD, Kirsten Moysich, PhD
Journal: Blood
Blood (2009) 114 (22): 168.
https://doi.org/10.1182/blood.V114.22.168.168
Published: 2009
Journal Articles

Polymorphisms in DNA repair genes and therapeutic outcomes of AML patients from SWOG clinical trials

Free
Clinical Trials & Observations
Nataliya Kuptsova, Kenneth J. Kopecky, John Godwin, Jeanne Anderson, Ashraful Hoque, Cheryl L. Willman, Marilyn L. Slovak, Christine B. Ambrosone
Journal: Blood
Blood (2007) 109 (9): 3936–3944.
https://doi.org/10.1182/blood-2006-05-022111
Published: 2007