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MinHong Yan
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Journal Articles

iPSC-derived, multiplex-engineered CD8αβT cells deliver antigen-specific, potent, and durable tumor cytotoxicity without CD4αβT support – powering scalable, off-the-shelf allogeneic αβT cell therapy in hematological malignancies

Free
Chih-Lung Chen, Jhang-Sian Yu, Chia-Hung Lin, Po-Fan Chu, Lin-Yu Liao, Wan-Chen Tsai, Yi-Han Dai, Ming-Chin Ko, Annie Yi-Ting Lai, Chun-Yu Lin, Wei-Ting Chen, Ying-Tsen Tung, Kuan-Hung Chen, Shao-Ju Weng, Pei-Kai Chen, Yi-Chiao Tseng, Ke-Hsun Hsu, Fang-Pei Chang, Fu-Fei Hsu, Yi-Ting Lai, Shiou-Ling Jian, Chien-Yu Hsu, Darien Zhing Herr Chan, Yo-Cheun Lin, Jin-Yi Lu, Hsin-Hua Cho, Cheng-Kai Wang, Lee-Yieng Lim, Tzu-Chien Kuo, Yun Gao, Pei-Chun Wu, Ta-Hsun Liao, Lien-Szu Wu, Jen-Chih Chi, Ching-Ying Huang, Ao Hu, MinHong Yan, Haitao Wang, Alex Shih-Min Huang
Journal: Blood
Blood (2025) 146 (Supplement 1): 2327.
https://doi.org/10.1182/blood-2025-2327
Published: 2025
Journal Articles

Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice

Free
Vedran Radojcic, Katelyn Paz, Jooho Chung, Jing Du, Eric T. Perkey, Ryan Flynn, Sanja Ivcevic, Michael Zaiken, Ann Friedman, Minhong Yan, Maria A. Pletneva, Stefanie Sarantopoulos, Christian W. Siebel, Bruce R. Blazar, Ivan Maillard
Journal: Blood
Blood (2018) 132 (20): 2188–2200.
https://doi.org/10.1182/blood-2018-03-841155
Published: 2018
Includes: Supplemental data
Journal Articles

Notch Signaling Mediated By Dll1/4 Notch Ligands Controls the Pathogenesis of Both Multi-Organ System Non-Sclerodermatous and Sclerodermatous Chronic Graft-Versus-Host Disease

Free
Vedran Radojcic, MD, Ryan P Flynn, PhD, Jooho Chung, BS, Jing Du, Eric Perkey, BS, Katelyn Paz, Michael Zaiken, Ann Friedman, Minhong Yan, PhD, Christian W. Siebel, PhD, Bruce R. Blazar, MD, Ivan Maillard, MD PhD
Journal: Blood
Blood (2016) 128 (22): 805.
https://doi.org/10.1182/blood.V128.22.805.805
Published: 2016
Journal Articles

Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease

Free
Jooho Chung, BS, Christen L. Ebens, MDMPH, Vedran Radojcic, MD, Ute Koch, PhD, Ann Friedman, BS, Ivy T. Tran, BS, Qian Chai, PhD, Lucas Onder, PhD, Minhong Yan, PhD, Pavan Reddy, MD, Bruce R. Blazar, MD, Burkhard Ludewig, PhD, Christian W. Siebel, PhD, Freddy Radtke, PhD, Ivan Maillard, MD PhD
Journal: Blood
Blood (2014) 124 (21): 841.
https://doi.org/10.1182/blood.V124.21.841.841
Published: 2014
Journal Articles

Loss of Notch Receptor-Ligand Engagement Leads to Increased Hematopoietic Stem and Progenitor Cell Egress and Mobilization

Free
Lan Zhou, MD PhD, Weihuan Wang, MD PhD, Grant Zimmerman, Jay Myers, MS, Yuanshuai Huang, MD PhD, Vionnie W.C. Yu, PhD, Dan Huang, MD PhD, Shuiliang Yu, PhD, Yiwei Wang, MD PhD, Xiaoran Huang, MD, Jeongsup Shim, PhD, Minhong Yan, PhD, John Lowe, MD, Wei Xin, MD PhD, Pamela Stanley, PhD BSc, David T. Scadden, MD, Alex Y Huang, MD PhD, Christian W. Siebel, PhD
Journal: Blood
Blood (2014) 124 (21): 652.
https://doi.org/10.1182/blood.V124.21.652.652
Published: 2014
Journal Articles

Delta-Like Notch Ligands Expressed By Host Non-Hematopoietic Radioresistant Cells Regulate Graft-Versus-Host Disease and Extrathymic T Cell Development After Bone Marrow Transplantation

Free
Christen L Ebens, MD, MPH, Jooho Chung, BS, Ute Koch, PhD, Ivy T Tran, BS, Ashley R Sandy-Sloat, PhD, Ann Friedman, BS, Bruce R Blazar, MD, Pavan Reddy, MD, Minhong Yan, PhD, Christian W Siebel, PhD, Freddy Radtke, PhD, Ivan Maillard, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2003.
https://doi.org/10.1182/blood.V122.21.2003.2003
Published: 2013
Journal Articles

LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance

Free
Sung-Uk Lee, Manami Maeda, Yuichi Ishikawa, Sierra Min Li, Anne Wilson, Adrian M. Jubb, Nagisa Sakurai, Lihong Weng, Emma Fiorini, Freddy Radtke, Minhong Yan, H. Robson MacDonald, Ching-Cheng Chen, Takahiro Maeda
Journal: Blood
Blood (2013) 121 (6): 918–929.
https://doi.org/10.1182/blood-2012-03-418103
Published: 2013
Includes: Supplemental data
Journal Articles

In Vivo Blockade of Individual Notch Ligands and Receptors Provides a New Targeted Therapeutic Approach In Graft-Versus-Host Disease

Free
Ivy T Tran, BS, Ashley R Sandy, BS, Alexis Carulli, BS, Gloria T Shan, BS, Vedran Radojcic, MD, Ann Friedman, BS, Amy Shelton, Linda C Samuelson, PhD, Minhong Yan, PhD, Christian W Siebel, PhD, Ivan Maillard, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 819.
https://doi.org/10.1182/blood.V118.21.819.819
Published: 2011
Journal Articles

LRF Maintains HSC Homeostasis by Preventing Lymphoid-Primed LT-HSCs From Excessive Differentiation

Free
Sung-Uk Lee, PhD, Manami Maeda, MD, PhD, Anne E. Wilson, Min Li, PhD, Yuichi Ishikawa, MD, PhD, Adrian M. Judd, PhD, Nagisa Sakurai, PhD, Emma Fiorini, PhD, Freddy Radtke, PhD, Minhong Yan, PhD, Hugh Robson Macdonald, PhD, Ching-Cheng Chen, Takahiro Maeda, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 44.
https://doi.org/10.1182/blood.V118.21.44.44
Published: 2011
Journal Articles

The Notch1-Dll4 signaling pathway regulates mouse postnatal lymphatic development

Free
Kyle Niessen, Gu Zhang, John Brady Ridgway, Hao Chen, Ganesh Kolumam, Christian W. Siebel, Minhong Yan
Journal: Blood
Blood (2011) 118 (7): 1989–1997.
https://doi.org/10.1182/blood-2010-11-319129
Published: 2011
Includes: Supplemental data
Journal Articles

Notch Repression by LRF Is Necessary for the Maintenance of Adult Hematopoietic Stem Cell Pool.

Free
Sung-UK Lee, PhD, Min Li, PhD, Manami Maeda, Nagisa Sakurai, Yuichi Ishikawa, MD, PhD, Freddy Radtke, Minhong Yan, Hugh Robson Macdonald, Takahiro Maeda, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2633.
https://doi.org/10.1182/blood.V116.21.2633.2633
Published: 2010
Journal Articles

ALK1 signaling regulates early postnatal lymphatic vessel development

Free
Kyle Niessen, Gu Zhang, John Brady Ridgway, Hao Chen, Minhong Yan
Journal: Blood
Blood (2010) 115 (8): 1654–1661.
https://doi.org/10.1182/blood-2009-07-235655
Published: 2010
Includes: Supplemental data