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Michael R Blackburn
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Journal Articles

Adenosine Signaling-Mediated Metabolic Reprogramming Regulates Erythropoiesis

Hong Liu, MD, Yujin Zhang, PhD, Angelo D'Alessandro, PhD, Travis Nemkov, Jacob Couturier, PhD, Shushan Zhao, PhD, Kirk C Hansen, PhD, Andrew T. Lovering, PhD, Robert Roach, PhD, Rodney E. Kellems, PhD, Holger K. Eltzschig, MD PhD, Michael R. Blackburn, PhD, Yang Xia, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2437.
https://doi.org/10.1182/blood.V128.22.2437.2437
Published: 2016
Journal Articles

Sustained Elevation of Adenosine-ADORA2B Signaling Promotes Chronic Pain through Neuro-Immune Interaction in Sickle Cell Disease

Morayo G. Adebiyi, BS, Xia Hu, MD, Jialie Luo, PhD, Kaiqi Sun, BS, Thanh-Thuy T. Le, MD PhD, Yujin Zhang, MD, Hongyu Wu, PhD, Hong Liu, MD, Aji Huang, BS, MS, Rodney E. Kellems, PhD, Michael R. Blackburn, PhD, Edgar T. Walters, PhD, Hongzhen Hu, PhD, Yang Xia, MD PhD
Journal: Blood
Blood (2015) 126 (23): 974.
https://doi.org/10.1182/blood.V126.23.974.974
Published: 2015
Journal Articles

Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity

Kaiqi Sun, Yujin Zhang, Mikhail V. Bogdanov, Hongyu Wu, Anren Song, Jessica Li, William Dowhan, Modupe Idowu, Harinder S. Juneja, Jose G. Molina, Michael R. Blackburn, Rodney E. Kellems, Yang Xia
Journal: Blood
Blood (2015) 125 (10): 1643–1652.
https://doi.org/10.1182/blood-2014-08-595751
Published: 2015
Journal Articles

Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Prevents Hypoxia-Induced Tissue Injury in High Altitude By Inducing 2,3-Bisphosphoglycerate

Hong Liu, MD, Yujin Zhang, PhD, Anren Song, PhD, Harry Karmouty Quintana, PhD, Almut Grenz, MD PhD, Hong Sun, MD PhD, Rodney E. Kellems, PhD, Holger Eltzschig, PhD, Robert Roach, PhD, Michael R. Blackburn, PhD, Yang Xia, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2664.
https://doi.org/10.1182/blood.V124.21.2664.2664
Published: 2014
Journal Articles

Functions and Regulation of Erythrocyte Equlibrative Nucleoside Transporter 1 (ENT1) in Acute Hypoxia Mediated Tissue Injury

Anren Song, PhD, Cheng Zhao, MD, Yujin Zhang, PhD, Jessica Li, PhD, Michael R. Blackburn, PhD, Almut Grenz, Holger Eltzschig, PhD, Rodney E. Kellems, PhD, Yang Xia, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2666.
https://doi.org/10.1182/blood.V124.21.2666.2666
Published: 2014
Journal Articles

Elevated Adenosine Signaling Via Adenosine A2B Receptor Induces Normal and Sickle Erythrocyte Sphingosine Kinase 1 Activity

Kaiqi Sun, BS, Yujin Zhang, PhD, Mikhail Bogdanov, PhD, William Dowhan, PhD, Modupe Idowu, MD, Harinder S. Juneja, MD, Michael R. Blackburn, PhD, Rodney E. Kellems, PhD, Yang Xia, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4067.
https://doi.org/10.1182/blood.V124.21.4067.4067
Published: 2014
Journal Articles

Adenosine Is A Common Factor Regulating Erythrocyte 2,3-Bisphosphate Induction In Normal Individuals At High Altitude and In Patients With Sickle Cell Disease

Yujin Zhang, Ph.D, Hong Liu, Kaiqi Sun, Anren Song, Ph.D, Harry Karmouty-Quintana, Ph.D, Ning-Yuan Chen, Almut Grenz, MD; Ph.D, Rodney E. Kellems, Modupe Idowu, MD, Harinder S. Juneja, MD, Robert Roach, Ph.D, Holger Eltzschig, Ph.D, Michael R. Blackburn, Ph.D, Yang Xia
Journal: Blood
Blood (2013) 122 (21): 952.
https://doi.org/10.1182/blood.V122.21.952.952
Published: 2013
Journal Articles

Gene therapy/bone marrow transplantation in ADA-deficient mice: roles of enzyme-replacement therapy and cytoreduction

Denise A. Carbonaro, Xiangyang Jin, Xingchao Wang, Xiao-Jin Yu, Nora Rozengurt, Michael L. Kaufman, Xiaoyan Wang, David Gjertson, Yang Zhou, Michael R. Blackburn, Donald B. Kohn
Journal: Blood
Blood (2012) 120 (18): 3677–3687.
https://doi.org/10.1182/blood-2012-02-408591
Published: 2012
Includes: Supplemental data
Journal Articles

P2Y 6 and vascular inflammation

Michael R. Blackburn
Journal: Blood
Blood (2011) 117 (8): 2304–2305.
https://doi.org/10.1182/blood-2011-01-327973
Published: 2011
Journal Articles

Detrimental Role of Excess Adenosine-Mediated 2,3-Diphosphoglycerate Induction in Erythrocyte Sickling and Novel Mechanism-Based Therapies.

Yujin Zhang, Yingbo Dai, Jiaming Wen, Rodney E. Kellems, Michael R Blackburn, Harinder S. Juneja, Yang Xia
Journal: Blood
Blood (2009) 114 (22): 906.
https://doi.org/10.1182/blood.V114.22.906.906
Published: 2009
Journal Articles

Adenosine receptors in regulation of dendritic cell differentiation and function

Sergey V. Novitskiy, Sergey Ryzhov, Rinat Zaynagetdinov, Anna E. Goldstein, Yuhui Huang, Oleg Y. Tikhomirov, Michael R. Blackburn, Italo Biaggioni, David P. Carbone, Igor Feoktistov, Mikhail M. Dikov
Journal: Blood
Blood (2008) 112 (5): 1822–1831.
https://doi.org/10.1182/blood-2008-02-136325
Published: 2008
Journal Articles

Neonatal bone marrow transplantation of ADA-deficient SCID mice results in immunologic reconstitution despite low levels of engraftment and an absence of selective donor T lymphoid expansion

Denise A. Carbonaro, Xiangyang Jin, Daniel Cotoi, Tiejuan Mi, Xiao-Jin Yu, Dianne C. Skelton, Frederick Dorey, Rodney E. Kellems, Michael R. Blackburn, Donald B. Kohn
Journal: Blood
Blood (2008) 111 (12): 5745–5754.
https://doi.org/10.1182/blood-2007-08-103663
Published: 2008
Journal Articles

A 2A adenosine receptors and C/EBPβ are crucially required for IL-10 production by macrophages exposed to Escherichia coli

Balázs Csóka, Zoltán H. Németh, László Virág, Pál Gergely, S. Joseph Leibovich, Pál Pacher, Chun-Xiao Sun, Michael R. Blackburn, E. Sylvester Vizi, Edwin A. Deitch, György Haskó
Journal: Blood
Blood (2007) 110 (7): 2685–2695.
https://doi.org/10.1182/blood-2007-01-065870
Published: 2007
Includes: Supplemental data