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Journal Articles

RNA-Seq Analysis of Clonal Hematopoiesis (CHIP) Blood Leukocytes Shows Dysregulation of Neutrophil / Innate Immunity-Related Genes

Elina K Cook, MSc, Richard N Armstrong, PhD, Eshita Sharma, PhD, Brooke Snetsinger, MSc, Jacqueline Boultwood, PhD, Rena Buckstein, MD FRCPC, Andrea Pellagatti, PhD, Michael J. Rauh, MD PhD

Blood (2018) 132 (Supplement 1): 3843.

https://doi.org/10.1182/blood-2018-99-116128

Published: 2018

Journal Articles

Validation and Clinical Impact of the Oncomine Myeloid Targeted DNA and RNA Ion Semiconductor Sequencing Assay

Christina Ferrone, BScH, Henry Wong, PhD, Laura Semenuk, Brooke Snetsinger, MSc, Xiao Zhang, David Good, MD FRCPC, Graeme Quest, MSc, MD FRCPC, Harriet Feilotter, PhD FCCMG, FACMG, Michael J. Rauh, MD PhD

Blood (2018) 132 (Supplement 1): 5523.

https://doi.org/10.1182/blood-2018-99-116576

Published: 2018

Journal Articles

Somatic Mutations Associated with Myeloid Transformation of RUNX1 -Mutated Familial Platelet Disorders with Propensity to Myeloid Malignancies Using Targeted Next-Generation Sequencing

Bruno K L Duarte, Samuel S Medina, MD, Gabriela G Yamaguti Hayakawa, MD, Fernando Ferreira Costa, MD PhD, Michael J. Rauh, MD PhD, Margareth C Ozelo, MD PhD

Blood (2017) 130 (Supplement 1): 2482.

https://doi.org/10.1182/blood.V130.Suppl_1.2482.2482

Published: 2017

Journal Articles

Feeding the Fire: The Comorbid and Inflammatory Backdrop of Clonal Hematopoiesis of Indeterminate Potential (CHIP) By Mutation Subtype

Elina K Cook, Terumi Izukawa, Sherylan Young, Gili Rosen, Mina Jamali, Brooke Snetsinger, Dylan Johnson, Eva Bain, Jamie Hilland, Jonah Buckstein, Janika Francis, Bushra Momtaz, Rena Buckstein, MD, Michael J. Rauh, MD PhD

Blood (2017) 130 (Supplement 1): 426.

https://doi.org/10.1182/blood.V130.Suppl_1.426.426

Published: 2017

Journal Articles

Tet2 Deficiency Leads to an Increased Inflammatory Phenotype in Murine Macrophages

Alyssa Cull, MSc, Brooke Snetsinger, MSc, Michael J. Rauh, MD PhD

Blood (2016) 128 (22): 708.

https://doi.org/10.1182/blood.V128.22.708.708

Published: 2016

Journal Articles

Microenvironmental Links Between TET2/DNMT3A Mutations and Arginase 1 Overexpression in Human MDS/CMML

Alyssa Cull, MSc, Brooke Snetsinger, MSc, David Good, MD, Rena Buckstein, MD, Richard A. Wells, MD DPhil, Michael J. Rauh, MD PhD

Blood (2016) 128 (22): 3164.

https://doi.org/10.1182/blood.V128.22.3164.3164

Published: 2016

Journal Articles

TNF-Alpha Promotes Clonal Expansion of Tet2 Deficient Bone Marrow Progenitors in MDS

Samuel Ojo Abegunde, MD MSc., Michael J. Rauh, MD PhD

Blood (2016) 128 (22): 731.

https://doi.org/10.1182/blood.V128.22.731.731

Published: 2016

Journal Articles

Differential Expression of TCF3 Target Genes Defines Subclasses of Diffuse Large B-Cell Lymphoma with Striking Differences in Clinical Outcome Following R-CHOP Therapy

Kathrin Tyryshkin, PhD, Yi D Li, MD, David Good, MD, Lois E. Shepherd, MD, Tara Baetz, MD FRCPC, Michael J. Rauh, MD PhD, David P. LeBrun, MD

Blood (2016) 128 (22): 3037.

https://doi.org/10.1182/blood.V128.22.3037.3037

Published: 2016

Journal Articles

Tet2 -Deficient Bone Marrow Progenitors Have a Proliferative Advantage in the Presence of TNF-Alpha and IFN-Gamma: Implications for Clonal Dominance in Inflammaging and MDS

Samuel Ojo Abegunde, MD BSc, MBBS, Michael J. Rauh, MD PhD

Blood (2015) 126 (23): 2850.

https://doi.org/10.1182/blood.V126.23.2850.2850

Published: 2015

Journal Articles

Tet2 Is a Novel Regulator of Murine Macrophage Differentiation and Polarization

Alyssa Cull, MSc, Brooke Snetsinger, MSc, Michael J. Rauh, MD PhD

Blood (2015) 126 (23): 646.

https://doi.org/10.1182/blood.V126.23.646.646

Published: 2015

Journal Articles

Suspicious, Non-MDS-Diagnostic Bone Marrows Have a High Incidence of Clonal Hematopoiesis (CHIP), with MDS-like Clone Size but Restricted Mutation Burden

Brooke Snetsinger, MSc, Emily Heath, BSc, Michael J. Rauh, MD PhD

Blood (2015) 126 (23): 1668.

https://doi.org/10.1182/blood.V126.23.1668.1668

Published: 2015

Journal Articles

Testing for Heparin Induced Thrombocytopenia: Comparison of Practice at an Academic Center with Choosing Wisely Guidelines

DiMaria C Erica, MD, Alex Trussler, MD, Dyba Janique, MD, David Lee, MD FRCPC, Michael J. Rauh, MD PhD, Paula D. James, MD FRCPC, Wilma Hopman, MA, Annette E Hay, MB ChB

Blood (2015) 126 (23): 3469.

https://doi.org/10.1182/blood.V126.23.3469.3469

Published: 2015

Journal Articles

Myeloid-Derived Suppressor Cell (MDSC) Dynamics In FVIII-Exposed Hemophilia A Mice: Novel Therapeutic Implications

Brooke Snetsinger, MSc, Caroline Lin, BSc, Willy Weng, BSc, Alyssa Cull, MSc, Kate Sponagle, Christine Hough, PhD, David Lillicrap, Michael J. Rauh, MD, PhD

Blood (2013) 122 (21): 3569.

https://doi.org/10.1182/blood.V122.21.3569.3569

Published: 2013

Journal Articles

Increased Arginase 1 Expression In Human MDS, CMML and Murine Models Points To Dysregulation Of Common Immunosuppressive Signaling Networks

Alyssa Cull, MSc, Brooke Snetsinger, MSc, Iqra Mumal, BSc, Flora Shan, BSc, David Good, MD, FRCPC, Michael J. Rauh, MD, PhD

Blood (2013) 122 (21): 1578.

https://doi.org/10.1182/blood.V122.21.1578.1578

Published: 2013

Journal Articles

Arginase and YKL-40, Effectors of Immunosuppressive Myeloid Cells, Are Over-Expressed In the Bone Marrow of Most Chronic Myelomonocytic Leukemia Patients, and Are Potential Prognostic Biomarkers In Myelodysplastic Syndrome

Michael J. Rauh, MD, PhD, Deeksha Mahendru, BSc, Roman Shapiro, BSc, Alden Chesney, MD, David Good, MD, Marciano D. Reis, MD, Adam Lam, Gerald Krystal, PhD, Rena Buckstein, MD, FRCPC, Richard A. Wells, MD, DPhil

Blood (2010) 116 (21): 1855.

https://doi.org/10.1182/blood.V116.21.1855.1855

Published: 2010

Journal Articles

Iron Overload Accelerates Development of Leukaemia: Evidence From a Mouse Model

Lap Shu Alan Chan, MSc, Lilly Chunhong Gu, MD, PhD, Michael J. Rauh, MD, PhD, Richard A. Wells, MD, DPhil

Blood (2010) 116 (21): 122.

https://doi.org/10.1182/blood.V116.21.122.122

Published: 2010

Journal Articles

Single Nucleotide Polymorphism Array (SNP-A) Genomic Profiling of Mantle Cell Lymphoma (MCL) Against a Large Control Database Reveals Recurring Copy Number Alterations (CNAs) and Copy Neutral Loss of Heterozygosity (CN-LOH)

Michael J. Rauh, MD, PhD, Juraj Bodo, MD, Eric Hsi, MD, Bill Richendollar, Yuka Sugimoto, MD, PhD, Jaroslaw P Maciejewski, MD, PhD, FACP, Christine L. O'Keefe, PhD, Stephen D. Smith, MD

Blood (2010) 116 (21): 2001.

https://doi.org/10.1182/blood.V116.21.2001.2001

Published: 2010

NARROW

RNA-Seq Analysis of Clonal Hematopoiesis (CHIP) Blood Leukocytes Shows Dysregulation of Neutrophil / Innate Immunity-Related Genes

Validation and Clinical Impact of the Oncomine Myeloid Targeted DNA and RNA Ion Semiconductor Sequencing Assay

Somatic Mutations Associated with Myeloid Transformation of RUNX1 -Mutated Familial Platelet Disorders with Propensity to Myeloid Malignancies Using Targeted Next-Generation Sequencing

Feeding the Fire: The Comorbid and Inflammatory Backdrop of Clonal Hematopoiesis of Indeterminate Potential (CHIP) By Mutation Subtype

Tet2 Deficiency Leads to an Increased Inflammatory Phenotype in Murine Macrophages

Microenvironmental Links Between TET2/DNMT3A Mutations and Arginase 1 Overexpression in Human MDS/CMML

TNF-Alpha Promotes Clonal Expansion of Tet2 Deficient Bone Marrow Progenitors in MDS

Differential Expression of TCF3 Target Genes Defines Subclasses of Diffuse Large B-Cell Lymphoma with Striking Differences in Clinical Outcome Following R-CHOP Therapy

Tet2 -Deficient Bone Marrow Progenitors Have a Proliferative Advantage in the Presence of TNF-Alpha and IFN-Gamma: Implications for Clonal Dominance in Inflammaging and MDS

Tet2 Is a Novel Regulator of Murine Macrophage Differentiation and Polarization

Suspicious, Non-MDS-Diagnostic Bone Marrows Have a High Incidence of Clonal Hematopoiesis (CHIP), with MDS-like Clone Size but Restricted Mutation Burden

Testing for Heparin Induced Thrombocytopenia: Comparison of Practice at an Academic Center with Choosing Wisely Guidelines

Myeloid-Derived Suppressor Cell (MDSC) Dynamics In FVIII-Exposed Hemophilia A Mice: Novel Therapeutic Implications

Increased Arginase 1 Expression In Human MDS, CMML and Murine Models Points To Dysregulation Of Common Immunosuppressive Signaling Networks

Arginase and YKL-40, Effectors of Immunosuppressive Myeloid Cells, Are Over-Expressed In the Bone Marrow of Most Chronic Myelomonocytic Leukemia Patients, and Are Potential Prognostic Biomarkers In Myelodysplastic Syndrome

Iron Overload Accelerates Development of Leukaemia: Evidence From a Mouse Model

Single Nucleotide Polymorphism Array (SNP-A) Genomic Profiling of Mantle Cell Lymphoma (MCL) Against a Large Control Database Reveals Recurring Copy Number Alterations (CNAs) and Copy Neutral Loss of Heterozygosity (CN-LOH)

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American Society of Hematology

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American Society of Hematology

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