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Michael Hadler, MSc
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Journal Articles

Patient Derived Xenograft (PDX) Models Recapitulate the Genomic-Driver Composition of Acute Leukemia Samples

Andrei V. Krivtsov, PhD, Xujun Wang, MD, Noushin Rahnamay Farnoud, PhD, Michael Hadler, MSc, Marta Sanchez Martin, Kristina M. Knapp, BS, Eytan M. Stein, Doron Lipson, PhD, Michelle K. Nahas, PhD, Philip J. Stephens, PhD, Eric M Sanford, BS, Kai Wang, MDPhD, Garrett M Frampton, PhD, Tim Brennan, PhD, Geoff A. Otto, PhD, Roman Yelensky, PhD, Vincent Miller, MD, Ross L. Levine, MD, Adolfo A. Ferrando, MD PhD, Scott A. Armstrong, MD PhD
Journal: Blood
Blood (2014) 124 (21): 286.
https://doi.org/10.1182/blood.V124.21.286.286
Published: 2014
Journal Articles

Structure-Guided Design of DOT1L Methyltransferase Inhibitors By a Novel, Label Free Assay Platform

Joanna S. Yi, MD, Alex Federation, Jun Qi, PhD, Sirano Dhe-Paganon, PhD, Michael Hadler, MSc, Xiang Xu, PhD, Anthony Varca, Roodolph St. Pierre, Scott A. Armstrong, MD PhD, James E. Bradner
Journal: Blood
Blood (2014) 124 (21): 4811.
https://doi.org/10.1182/blood.V124.21.4811.4811
Published: 2014
Journal Articles

Patient Derived Xenograft (PDX) Models Faithfully Recapitulate The Genetic Composition Of Primary AML

Andrei V. Krivtsov, PhD, Wang Xujun, MD, Noushin Rahnamay Farnoud, PhD, Michael Hadler, MSc, Kristina M. Knapp, BS, Eytan M Stein, MD, Martin S. Tallman, MD, Amy L Donahue, MS, Doron Lipson, PhD, Michelle K. Nahas, PhD, Philip J. Stephens, PhD, Eric M Sanford, BS, Kai Wang, MD PhD, Garrett M Frampton, PhD, Tim Brennan, PhD, Geoff A. Otto, PhD, Roman Yelensky, PhD, Vincent A. Miller, MD, Ross L. Levine, MD, Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1328.
https://doi.org/10.1182/blood.V122.21.1328.1328
Published: 2013
Journal Articles

Myeloid Leukemia Cells With MLL partial Tandem Duplication Are Sensitive To Pharmacological Inhibition Of The H3K79 Methyltransferase DOT1L

Michael W.M. Kühn, MD, Michael Hadler, MSc, Scott R. Daigle, PhD, Chun-Wei Chen, PhD, Amit U. Sinha, PhD, Andrei V. Krivtsov, PhD, Edward J. Olhava, PhD, Michael A. Caligiuri, MD, James E Bradner, MD, Roy M. Pollock, PhD, Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1256.
https://doi.org/10.1182/blood.V122.21.1256.1256
Published: 2013