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Journal Articles

Analysis of Mechanisms of Blast Crisis in Chronic Myeloid Leukemia By Whole Genome Sequencing

Kristina Loy, Melanie Zenger, Manja Meggendorfer, PhD, Stephan Hutter, PhD, Wolfgang Kern, MD, Torsten Haferlach, MD, Claudia Haferlach, MD, Constance Baer, PhD

Blood (2020) 136 (Supplement 1): 19.

https://doi.org/10.1182/blood-2020-140688

Published: 2020

Journal Articles

Artificial Intelligence Substantially Supports Chromosome Banding Analysis Maintaining Its Strengths in Hematologic Diagnostics Even in the Era of Newer Technologies

Claudia Haferlach, MD, Siegfried Hänselmann, PhD, Wencke Walter, PhD, Sarah Volkert, Melanie Zenger, Wolfgang Kern, MD, Anna Stengel, PhD, Thomas Lörch, PhD, Torsten Haferlach, MD

Blood (2020) 136 (Supplement 1): 47–48.

https://doi.org/10.1182/blood-2020-137463

Published: 2020

Journal Articles

Comprehensive Molecular Characterization of Myeloid Malignancies with 9q Deletion

Luise Hartmann, PhD, Torsten Haferlach, MD, Manja Meggendorfer, PhD, Annette Fasan, PhD, Anna Stengel, PhD, Melanie Zenger, Kathleen Zieschang, Wolfgang Kern, MD, Claudia Haferlach, MD

Blood (2017) 130 (Supplement 1): 2953.

https://doi.org/10.1182/blood.V130.Suppl_1.2953.2953

Published: 2017

Journal Articles

In Chronic Lymphocytic Leukemia the Gain of the Short Arm of Chromosome 2 Is Highly Associated with an Unmutated IGHV status, 11q/ ATM Deletion, SF3B1 Mutation and a Complex Karyotype

Claudia Haferlach, MD, Sabine Jeromin, PhD, Anna Stengel, PhD, Manja Meggendorfer, PhD, Melanie Zenger, Wolfgang Kern, MD, Torsten Haferlach, MD

Blood (2016) 128 (22): 4379.

https://doi.org/10.1182/blood.V128.22.4379.4379

Published: 2016

Journal Articles

Cytogenetic and Molecular Genetic Clonal Evolution in CLL Is Associated with an Unmutated IGHV Status and Frequently Leads to a Combination of Loss of 17p and TP53 mutation

Claudia Haferlach, MD, Sabine Jeromin, PhD, Niroshan Nadarajah, M.Sc., Melanie Zenger, Wolfgang Kern, MD, Torsten Haferlach, MD

Blood (2016) 128 (22): 3213.

https://doi.org/10.1182/blood.V128.22.3213.3213

Published: 2016

Journal Articles

Myeloid Malignancies with Isolated 7q Deletion Can be Further Characterized By Their Accompanying Molecular Mutations

Claudia Haferlach, MD, Annette Fasan, PhD, Manja Meggendorfer, PhD, Melanie Zenger, Susanne Schnittger, PhD, Wolfgang Kern, MD, Torsten Haferlach

Blood (2015) 126 (23): 3811.

https://doi.org/10.1182/blood.V126.23.3811.3811

Published: 2015

Journal Articles

Comparison of TP53 Alterations in Hematological Malignancies

Anna Stengel, PhD, Wolfgang Kern, MD, Torsten Haferlach, Susanne Schnittger, PhD, Melanie Zenger, Claudia Haferlach, MD

Blood (2015) 126 (23): 4819.

https://doi.org/10.1182/blood.V126.23.4819.4819

Published: 2015

Journal Articles

Abnormalities Detected By Array CGH and Fluorescence in Situ Hybridization in AML with Normal Karyotype Lacking Mutations in NPM1 , CEBPA , RUNX1 and MLL Partial Tandem Duplications Are Associated with Unfavorable Outcome

Claudia Haferlach, MD, Kathleen Zieschang, Susanne Schnittger, PhD, Tamara Alpermann, Melanie Zenger, Karolína Perglerová, Wolfgang Kern, MD, Torsten Haferlach

Blood (2015) 126 (23): 1371.

https://doi.org/10.1182/blood.V126.23.1371.1371

Published: 2015

Journal Articles

5q Deletions in MDS and MPN: The Accompanying Molecular Mutations Determine the Phenotype but TP53 Is Frequently Mutated in All Entities: MPN, MDS and MPN/MDS Overlap

Claudia Haferlach, MD, Manja Meggendorfer, PhD, Susanne Schnittger, PhD, Melanie Zenger, Wolfgang Kern, MD, Torsten Haferlach

Blood (2014) 124 (21): 1926.

https://doi.org/10.1182/blood.V124.21.1926.1926

Published: 2014

Journal Articles

A Comprehensive Cytogenetic and Molecular Genetic Characterization of Patients with T-PLL Revealed Two Distinct Genetic Subgroups and JAK3 Mutations As an Important Prognostic Marker

Anna Stengel, PhD, Wolfgang Kern, MD, Melanie Zenger, Karolina Perglerová, Susanne Schnittger, PhD, Torsten Haferlach, MD, Claudia Haferlach, MD

Blood (2014) 124 (21): 1639.

https://doi.org/10.1182/blood.V124.21.1639.1639

Published: 2014

Journal Articles

Targeting Genomic Heterogeneity of Adult Acute Lymphoblastic Leukemia

Annette Fasan, PhD, Melanie Zenger, Madlen Ulke, Wolfgang Kern, MD, Torsten Haferlach, MD, Claudia Haferlach, MD, Susanne Schnittger, PhD

Blood (2014) 124 (21): 2407.

https://doi.org/10.1182/blood.V124.21.2407.2407

Published: 2014

Journal Articles

Array Based Comparative Genomic Hybridization Detects Copy Number Alterations in 80.3% of Adult Acute Lymphoblastic Leukemia (ALL) with Normal Karyotype or Failed Chromosome Banding Analysis and Identifies a Subset with Only Submicroscopic Alterations Associated with Favorable Outcome

Claudia Haferlach, MD, Melanie Zenger, Torsten Haferlach, MD, Wolfgang Kern, MD, Susanne Schnittger, PhD

Blood (2014) 124 (21): 2409.

https://doi.org/10.1182/blood.V124.21.2409.2409

Published: 2014

Journal Articles

Gene Amplifications In 84 Patients With Acute Myeloid Leukemia and 31 Patients With Myelodysplastic Syndrome Investigated By Array CGH

Andreas Roller, PhD, Simone Weber, Alexander Kohlmann, PhD, Melanie Zenger, Marita Staller, Wolfgang Kern, MD, Susanne Schnittger, PhD, Torsten Haferlach, MD, Claudia Haferlach, MD

Blood (2013) 122 (21): 3724.

https://doi.org/10.1182/blood.V122.21.3724.3724

Published: 2013

Journal Articles

Targeted Next-Generation Sequencing Of 2,761 Genes Detects Copy Number States and Molecular Mutations In a Single Approach

Alexander Kohlmann, PhD, Andreas Roller, PhD, Sandra Weissmann, PhD, Sabrina Kuznia, MSc, Melanie Zenger, Wolfgang Kern, MD, Susanne Schnittger, PhD, Torsten Haferlach, MD, Claudia Haferlach, MD

Blood (2013) 122 (21): 1371.

https://doi.org/10.1182/blood.V122.21.1371.1371

Published: 2013

Journal Articles

Myelodysplastic Syndromes (MDS) With 20q Deletion Show a High Frequency Of Associated Cytogenetic and Molecular Lesions With An Association To U2AF1 , SRSF2 , and Prognostically Adverse ASXL1 Mutations

Ulrike Bacher, MD, Torsten Haferlach, MD, Susanne Schnittger, PhD, Melanie Zenger, Manja Meggendorfer, PhD, Andreas Roller, PhD, Vera Grossmann, PhD, Maria Theresa Krauth, MD, Sabine Jeromin, PhD, Tamara Alpermann, Alexander Kohlmann, PhD, Wolfgang Kern, MD, Claudia Haferlach, MD

Blood (2013) 122 (21): 657.

https://doi.org/10.1182/blood.V122.21.657.657

Published: 2013

Journal Articles

Array CGH Identifies Copy Number Changes In 10% Of 520 MDS Patients With Normal Karyotype: Deletions Encompass The Genes TET2 , DNMT3A , ETV6 , NF1 , RUNX1, and STAG2 and Are Associated With Shorter Survival

Claudia Haferlach, MD, Melanie Zenger, Marita Staller, Andreas Roller, PhD, Kathrin Raitner, Jinda Holzwarth, Wolfgang Kern, MD, Susanne Schnittger, PhD, Yasunobu Nagata, MD, Seishi Ogawa, MD, PhD, Alexander Kohlmann, PhD, Torsten Haferlach, MD

Blood (2013) 122 (21): 1516.

https://doi.org/10.1182/blood.V122.21.1516.1516

Published: 2013

Journal Articles

Acute Lymphoblastic Leukemia (ALL) With Low-Hypodiploid/Near-Triploid Karyotype Is a Specific Clinical Entity Characterized By a High TP53 Mutation Frequency

Verena Patterer, PhD, Melanie Zenger, Susanne Schnittger, PhD, Sandra Weissmann, PhD, Franziska Poetzinger, Alexander Kohlmann, PhD, Frauke Bellos, MD, Wolfgang Kern, MD, Torsten Haferlach, MD, Claudia Haferlach, MD

Blood (2013) 122 (21): 615.

https://doi.org/10.1182/blood.V122.21.615.615

Published: 2013

Journal Articles

RUNX1 Deletions Are a Novel Mechanism of Loss of Function in AML and Are Associated with Adverse Cytogenetics.

Claudia Haferlach, MD, Vera Grossmann, MSc, Melanie Zenger, Wolfgang Kern, MD, Torsten Haferlach, MD, Alexander Kohlmann, PhD, Susanne Schnittger, PhD

Blood (2012) 120 (21): 2517.

https://doi.org/10.1182/blood.V120.21.2517.2517

Published: 2012

Journal Articles

Acute Lymphoblastic Leukemia (ALL) with Low-Hypodiploid/near Triploid Karyotype Is a Specific Clinical Entity with Poor Outcome

Claudia Haferlach, MD, Melanie Zenger, Vera Grossmann, MSc, Alexander Kohlmann, PhD, Susanne Schnittger, PhD, Wolfgang Kern, MD, Torsten Haferlach, MD

Blood (2012) 120 (21): 1429.

https://doi.org/10.1182/blood.V120.21.1429.1429

Published: 2012

Journal Articles

Acute Erythroid Leukemia (AEL) Can Be Separated Into Distinct Prognostic Subsets Based On Cytogenetic and Molecular Genetic Characteristics

Vera Grossmann, MSc, Claudia Haferlach, MD, Susanne Schnittger, PhD, Ulrike Bacher, MD, Franziska Poetzinger, Sandra Weissmann, PhD, Andreas Roller, PhD, Christiane Eder, PhD, Annette Fasan, PhD, Melanie Zenger, Marita Staller, Wolfgang Kern, MD, Alexander Kohlmann, PhD, Torsten Haferlach, MD

Blood (2012) 120 (21): 1394.

https://doi.org/10.1182/blood.V120.21.1394.1394

Published: 2012

NARROW

Analysis of Mechanisms of Blast Crisis in Chronic Myeloid Leukemia By Whole Genome Sequencing

Artificial Intelligence Substantially Supports Chromosome Banding Analysis Maintaining Its Strengths in Hematologic Diagnostics Even in the Era of Newer Technologies

Comprehensive Molecular Characterization of Myeloid Malignancies with 9q Deletion

In Chronic Lymphocytic Leukemia the Gain of the Short Arm of Chromosome 2 Is Highly Associated with an Unmutated IGHV status, 11q/ ATM Deletion, SF3B1 Mutation and a Complex Karyotype

Cytogenetic and Molecular Genetic Clonal Evolution in CLL Is Associated with an Unmutated IGHV Status and Frequently Leads to a Combination of Loss of 17p and TP53 mutation

Myeloid Malignancies with Isolated 7q Deletion Can be Further Characterized By Their Accompanying Molecular Mutations

Comparison of TP53 Alterations in Hematological Malignancies

Abnormalities Detected By Array CGH and Fluorescence in Situ Hybridization in AML with Normal Karyotype Lacking Mutations in NPM1 , CEBPA , RUNX1 and MLL Partial Tandem Duplications Are Associated with Unfavorable Outcome

5q Deletions in MDS and MPN: The Accompanying Molecular Mutations Determine the Phenotype but TP53 Is Frequently Mutated in All Entities: MPN, MDS and MPN/MDS Overlap

A Comprehensive Cytogenetic and Molecular Genetic Characterization of Patients with T-PLL Revealed Two Distinct Genetic Subgroups and JAK3 Mutations As an Important Prognostic Marker

Targeting Genomic Heterogeneity of Adult Acute Lymphoblastic Leukemia

Array Based Comparative Genomic Hybridization Detects Copy Number Alterations in 80.3% of Adult Acute Lymphoblastic Leukemia (ALL) with Normal Karyotype or Failed Chromosome Banding Analysis and Identifies a Subset with Only Submicroscopic Alterations Associated with Favorable Outcome

Gene Amplifications In 84 Patients With Acute Myeloid Leukemia and 31 Patients With Myelodysplastic Syndrome Investigated By Array CGH

Targeted Next-Generation Sequencing Of 2,761 Genes Detects Copy Number States and Molecular Mutations In a Single Approach

Myelodysplastic Syndromes (MDS) With 20q Deletion Show a High Frequency Of Associated Cytogenetic and Molecular Lesions With An Association To U2AF1 , SRSF2 , and Prognostically Adverse ASXL1 Mutations

Array CGH Identifies Copy Number Changes In 10% Of 520 MDS Patients With Normal Karyotype: Deletions Encompass The Genes TET2 , DNMT3A , ETV6 , NF1 , RUNX1, and STAG2 and Are Associated With Shorter Survival

Acute Lymphoblastic Leukemia (ALL) With Low-Hypodiploid/Near-Triploid Karyotype Is a Specific Clinical Entity Characterized By a High TP53 Mutation Frequency

RUNX1 Deletions Are a Novel Mechanism of Loss of Function in AML and Are Associated with Adverse Cytogenetics.

Acute Lymphoblastic Leukemia (ALL) with Low-Hypodiploid/near Triploid Karyotype Is a Specific Clinical Entity with Poor Outcome

Acute Erythroid Leukemia (AEL) Can Be Separated Into Distinct Prognostic Subsets Based On Cytogenetic and Molecular Genetic Characteristics

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American Society of Hematology

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American Society of Hematology

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