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Journal Articles

Genotype-Phenotype Correlation in Congenital TTP: New Insights from a Multicentre Study with 121 Patients

Anette Anette Van Dorland, PhD, Magnus Mansouri Taleghani, MD, Kenneth Dale Friedman, MD, James George, MD, Ingrid Hrachovinova, PhD, Paul Knöbl, MD PhD, Bernhard Lammle, MD, Masanori Matsumoto, MD, Anne Sophie von Krogh, MD, Reinhard Schneppenheim, MDPhD, Isabella Aebi-Huber, Bütikofer Lukas, PhD, Zuzana Cermakova, PhD, Petter Quist-Paulsen, MD PhD, Deirdra Terrell, PhD, Sara K. Vesely, PhD MPH, Yoshihiro Fujimura, MD PhD, Johanna A. Kremer Hovinga Strebel, MD

Blood (2018) 132 (Supplement 1): 376.

https://doi.org/10.1182/blood-2018-99-112095

Published: 2018

Journal Articles

Inhibitory Effect of a Novel DNA Aptamer with Artificial Nucleic Bases for Von Willebrand Factor A1 Domain on Platelet Thrombosis Formation

Kazuya Sakai, MD, Hideo Yagi, MD, Masaki Hayakawa, MD, Tatsuhiko Someya, PhD, Kaori Harada, PhD, Masanori Matsumoto, MD

Blood (2018) 132 (Supplement 1): 2522.

https://doi.org/10.1182/blood-2018-99-113948

Published: 2018

Journal Articles

Ischemia-Reperfusion Injury with Pringle's Maneuver Induces Increasing of Unusually Large Von Willebrand Factor Multimers after Hepatectomy

Takahiro Yoshikawa, MD, Takeo Nomi, MDPhD, Kazuya Sakai, MD, Masaki Hayakawa, MD, Daisuke Hokuto, MDPhD, Satoshi Yasuda, MDPhD, Masayuki Sho, MDPhD, Masanori Matsumoto, MD

Blood (2017) 130 (Supplement 1): 3608.

https://doi.org/10.1182/blood.V130.Suppl_1.3608.3608

Published: 2017

Journal Articles

Investigator-Initiated Phase 2 Trial of Rituximab in Adult Japanese Patients with Treatment-Resistant Acquired Thrombotic Thrombocytopenic Purpura

Yoshitaka Miyakawa, Kazunori Imada, Tatsuo Ichinohe, MDPhD, Yusuke Yamane, MD, Kenji Nishio, Takayuki Abe, Yoshihiro Fujimura, MDPhD, Yasunori Ueda, MD, PhD, Masanori Matsumoto, MD PhD, Shinichiro Okamoto

Blood (2015) 126 (23): 4645.

https://doi.org/10.1182/blood.V126.23.4645.4645

Published: 2015

Journal Articles

Introduction of a Quick Assay for ADAMTS13 Activity Improved a Survival of Acquired TTP Patients Who Received Platelet Transfusions

Yumi Yoshii, MD, Masanori Matsumoto, MD PhD, Kurumatani Norio, MD PhD, Ayami Isonishi, BS, Masahito Uemura, MD PhD, Yuji Hori, PhD, Masaki Hayakawa, MD, Hideo Yagi, MD PhD, Charles L Bennett, MD PhD MPP, Yoshihiro Fujimura, MD PhD

Blood (2014) 124 (21): 4209.

https://doi.org/10.1182/blood.V124.21.4209.4209

Published: 2014

Journal Articles

Decreased Platelet Thrombus Size, Due to a Heightened Proteolysis of VWF By ADAMTS13, Is Quickly Restored after Valve Replacement in Aortic Stenosis Patients

Hideo Yagi, MD PhD, Masaki Hayakawa, MD, Naoko Yamaguchi, Keigo Yamashita, MD, Shigeki Taniguchi, MD PhD, Masanori Matsumoto, MD PhD, Kazuo Tsubaki, MD PhD, Yoshihiro Fujimura, MD PhD

Blood (2014) 124 (21): 2857.

https://doi.org/10.1182/blood.V124.21.2857.2857

Published: 2014

Journal Articles

HSCT-Associated Hepatic VOD Is Initiated With Preceding Appearance Of Unusually Large Von Willebrand Factor Multimers In Patient Plasmas

Masaki Hayakawa, MD, Masanori Matsumoto, MD, PhD, Yumi Yoshii, MD, Hideo Yagi, MD, PhD, Hiroshi Kimura, MD, PhD, Yoshihiro Fujimura, MD, PhD

Blood (2013) 122 (21): 3625.

https://doi.org/10.1182/blood.V122.21.3625.3625

Published: 2013

Journal Articles

Atypical Hemolytic Uremic Syndrome In Japan Characterized By The Inhibitory Antibody-Based Hemolytic Assay and The Gene Analysis

Yoko Yoshida, MS, Xinping Fan, MD, Yoshifumi Ohyama, PhD, Tetsuro Kokubo, PhD, Masanori Matsumoto, MD, PhD, Hideo Yagi, MD, PhD, Hiroko Shirotani-Ikejima, PhD, Toshiyuki Miyata, PhD, Yoshihiro Fujimura, MD, PhD

Blood (2013) 122 (21): 2318.

https://doi.org/10.1182/blood.V122.21.2318.2318

Published: 2013

Journal Articles

A Long-Term Phenotype Analysis Of 51 Patients With Upshaw–Schulman Syndrome In Japan, With Special References To Pregnancy and Renal Failure That Requires Hemodialysis

Yoshihiro Fujimura, MD, PhD, Yumi Yoshii, MD, Masanori Matsumoto, MD, PhD, Ayami Isonishi, BS, Masaki Hayakawa, MD, Yoko Yoshida, MS, Hideo Yagi, MD, PhD, Koichi Kokame, PhD, Toshiyuki Miyata, PhD

Blood (2013) 122 (21): 3545.

https://doi.org/10.1182/blood.V122.21.3545.3545

Published: 2013

Journal Articles

Analysis of Genetic and Predisposing Factors in Japanese Patients with Atypical Hemolytic Uremic Syndrome

Xinping Fan, MD, Yoko Yoshida, MS, Toshiyuki Miyata, PhD, Shigenori Honda, MD, PhD, Masanori Matsumoto, MD, PhD, Yoshihiro Fujimura, MD, PhD

Blood (2012) 120 (21): 3337.

https://doi.org/10.1182/blood.V120.21.3337.3337

Published: 2012

Journal Articles

Deficient ADAMTS13 Activity in Ticlopidine-Associated Thrombotic Thrombocytopenic Purpura (TTP) in Populations From Japan in 2012: Validation of Findings Initially Reported in the United States in 1998 and 2000.

Charles Bennett, MD, PhD, MPP, Masanori Matsumoto, MD, Peter Georgantopoulos, MPH, AM, Sony Jacob, MD, Brianne L Dunn, PharmD, Zaina Parvez Qureshi, PhD, MPH, Nicholas Bandarenko, III, MD, Hau C. Kwaan, MD, PhD, Jeffrey Winters, MD, Ravindra Sarode, MD, Joseph E Kiss, MD, Constance Danielson, MD, PhD, Thomas L. Ortel, MD, PhD, Thomas Raife, MD, William F Clark, MD, Gail Rock, PhD, MD, FRCP, X. Long Zheng, MD, PhD, Dennis Raisch, Ph.D., M.S., R.Ph., Yoshihiro Fujimura, MD, PhD

Blood (2012) 120 (21): 2203.

https://doi.org/10.1182/blood.V120.21.2203.2203

Published: 2012

Journal Articles

Anti-ADAMTS13 Inhibitor Boosting During Plasma Exchange Therapy Often Causes an Intractable Acquired Idiopathic TTP

Ayami Isonishi, BS, Masanori Matsumoto, MD, PhD, Friedrich Scheiflinger, PhD, Barbara Plaimauer, PhD, Charles Bennett, MD, PhD, MPP, Yoshihiro Fujimura, MD, PhD

Blood (2012) 120 (21): 1086.

https://doi.org/10.1182/blood.V120.21.1086.1086

Published: 2012

Journal Articles

The Ratio of ADAMTS13 to VWF-Propeptide Can Reflect the Disease Severity and the Extent of Inflammation of the Patients with Severe Sepsis or Septic Shock,

Kenji Nishio, MD, PhD, Hidetada Fukushima, MD, Tomoro Watanabe, MD, Tadahiko Seki, MD, Hideto Matsui, MD, PhD, Mitsuhiko Sugimoto, MD, PhD, Masanori Matsumoto, MD, PhD, Yoshihiro Fujimura, MD, PhD, Kazuo Okuchi, MD, PhD

Blood (2011) 118 (21): 3349.

https://doi.org/10.1182/blood.V118.21.3349.3349

Published: 2011

Journal Articles

A Large-Pore IEF Gel Electrophoresis Separates the Complex in Both of ADAMTS13 Bound to VWF and to the IgG Autoantibodies From the Unbound in Plasma Milieu

Masanori Matsumoto, MD, PhD, Ayami Isonishi, BS, Yuji Hori, BS, Masaki Hayakawa, MD, Kenji Soejima, PhD, Yoshihiro Fujimura, MD, PhD

Blood (2011) 118 (21): 1160.

https://doi.org/10.1182/blood.V118.21.1160.1160

Published: 2011

Journal Articles

Quantitative Analysis of the Domain-Specific Autoantibodies to ADAMTS13 in Patients with Acquired Thrombotic Thrombocytopenic Purpura

Atsuko Igari, Takanori Moriki, MD, PhD, Yusuke Yamaguchi, Terumichi Nakagawa, Hideo Wada, MD, Masanori Matsumoto, MD, PhD, Yoshihiro Fujimura, MD, PhD, Kenji Soejima, PhD, Mitsuru Murata, MD

Blood (2011) 118 (21): 1167.

https://doi.org/10.1182/blood.V118.21.1167.1167

Published: 2011

Journal Articles

Characterization of Two Patient Groups with Acquired Idiopathic Thrombotic Thrombocytopenic Purpura, Defined by ADAMTS13 (n=195) and/or Classic Pentad (n=89).

Masanori Matsumoto, MD, Ayami Isonishi, BS, Seiji Kato, PhD, Hiromichi Ishizashi, PhD, Hideo Yagi, MD, Yoshihiro Fujimura, MD

Blood (2009) 114 (22): 3505.

https://doi.org/10.1182/blood.V114.22.3505.3505

Published: 2009

Journal Articles

Natural History of 33 Patients with Upshaw-Schulman Syndrome Has Revealed That All the Gravida Develop Thrombocytopenia, Often Followed by Thrombotic Microangiopathy with Stillbirth.

Blood (2007) 110 (11): 3211.

https://doi.org/10.1182/blood.V110.11.3211.3211

Published: 2007

Journal Articles

Analysis of ADAMTS13 and Its IgG-Autoantibodies in 170 Patients with Connective Tissue Disease-Associated Thrombotic Microangiopathy Indicates More Than 2 Types on Its Pathogenesis.

Tomomi Matsuyama, MD, Masanori Matsumoto, MD, Ayami Isonishi, MD, Shigeko Inokuma, MD, Yoshihiro Fujimura, MD

Blood (2007) 110 (11): 1322.

https://doi.org/10.1182/blood.V110.11.1322.1322

Published: 2007

Journal Articles

Plasma ADAMTS13 Activity Markedly Decreases in Patients with Severe Acute Pancreatitis: Its Potential Role on the Development of Multiorgan Failure.

Chie Morioka, MD, Masahito Uemura, MD, Tomomi Matsuyama, MD, Masanori Matsumoto, MD, Seiji Kato, MD, Masatohsi Ishikawa, MD, Hiromichi Ishizashi, MD, Masao Fujimoto, MD, Tatsuhiro Tsujimoto, MD, Kenji Nishio, MD, Kazuo Okuchi, MD, Yoshihiro Fujimura, MD, Hiroshi Fukui, MD

Blood (2007) 110 (11): 2160.

https://doi.org/10.1182/blood.V110.11.2160.2160

Published: 2007

Journal Articles

Clinical and Outcomes Findings for Thrombotic Thrombocytopenic Purpura among 467 Persons with Severely Versus Not Severely Deficient ADAMTS-13 Levels.

Charles L. Bennett, MD, PhD, MPP, Thanh Ha Luu, BA, Anaadriana Zakarija, MD, Hau C. Kwaan, MD, PhD, Nicholas Bandarenko, MD, Dilip K. Pandey, MBBS, MS, PhD, John F. Cursio, MS, June M. McKoy, MD, JD, MPH, Charlie Buffie, BA, Jeffrey L. Winters, MD, Thomas L. Ortel, MD, Ravindra Sarode, MD, X. Long Zheng, MD, PhD, Thomas J. Raife, MD, Masanori Matsumoto, MD, PhD, Yoshihiro Fujimura, MD, PhD, Gail A. Rock, MD, PhD

Blood (2007) 110 (11): 2088.

https://doi.org/10.1182/blood.V110.11.2088.2088

Published: 2007

NARROW

Genotype-Phenotype Correlation in Congenital TTP: New Insights from a Multicentre Study with 121 Patients

Inhibitory Effect of a Novel DNA Aptamer with Artificial Nucleic Bases for Von Willebrand Factor A1 Domain on Platelet Thrombosis Formation

Ischemia-Reperfusion Injury with Pringle's Maneuver Induces Increasing of Unusually Large Von Willebrand Factor Multimers after Hepatectomy

Investigator-Initiated Phase 2 Trial of Rituximab in Adult Japanese Patients with Treatment-Resistant Acquired Thrombotic Thrombocytopenic Purpura

Introduction of a Quick Assay for ADAMTS13 Activity Improved a Survival of Acquired TTP Patients Who Received Platelet Transfusions

Decreased Platelet Thrombus Size, Due to a Heightened Proteolysis of VWF By ADAMTS13, Is Quickly Restored after Valve Replacement in Aortic Stenosis Patients

HSCT-Associated Hepatic VOD Is Initiated With Preceding Appearance Of Unusually Large Von Willebrand Factor Multimers In Patient Plasmas

Atypical Hemolytic Uremic Syndrome In Japan Characterized By The Inhibitory Antibody-Based Hemolytic Assay and The Gene Analysis

A Long-Term Phenotype Analysis Of 51 Patients With Upshaw–Schulman Syndrome In Japan, With Special References To Pregnancy and Renal Failure That Requires Hemodialysis

Analysis of Genetic and Predisposing Factors in Japanese Patients with Atypical Hemolytic Uremic Syndrome

Deficient ADAMTS13 Activity in Ticlopidine-Associated Thrombotic Thrombocytopenic Purpura (TTP) in Populations From Japan in 2012: Validation of Findings Initially Reported in the United States in 1998 and 2000.

Anti-ADAMTS13 Inhibitor Boosting During Plasma Exchange Therapy Often Causes an Intractable Acquired Idiopathic TTP

The Ratio of ADAMTS13 to VWF-Propeptide Can Reflect the Disease Severity and the Extent of Inflammation of the Patients with Severe Sepsis or Septic Shock,

A Large-Pore IEF Gel Electrophoresis Separates the Complex in Both of ADAMTS13 Bound to VWF and to the IgG Autoantibodies From the Unbound in Plasma Milieu

Quantitative Analysis of the Domain-Specific Autoantibodies to ADAMTS13 in Patients with Acquired Thrombotic Thrombocytopenic Purpura

Characterization of Two Patient Groups with Acquired Idiopathic Thrombotic Thrombocytopenic Purpura, Defined by ADAMTS13 (n=195) and/or Classic Pentad (n=89).

Natural History of 33 Patients with Upshaw-Schulman Syndrome Has Revealed That All the Gravida Develop Thrombocytopenia, Often Followed by Thrombotic Microangiopathy with Stillbirth.

Analysis of ADAMTS13 and Its IgG-Autoantibodies in 170 Patients with Connective Tissue Disease-Associated Thrombotic Microangiopathy Indicates More Than 2 Types on Its Pathogenesis.

Plasma ADAMTS13 Activity Markedly Decreases in Patients with Severe Acute Pancreatitis: Its Potential Role on the Development of Multiorgan Failure.

Clinical and Outcomes Findings for Thrombotic Thrombocytopenic Purpura among 467 Persons with Severely Versus Not Severely Deficient ADAMTS-13 Levels.

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American Society of Hematology

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American Society of Hematology

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