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Martin Trbusek, PhD
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Journal Articles

Assessment of p53 and ATM Functionality in Chronic Lymphocytic Leukemia By Multiplex Ligation-Dependent Probe Amplification

Doreen te Raa, Perry Moerland, Alexander Leeksma, Ingrid Derks, Martin Loden, Veronika Navrkalova, Martin Trbusek, PhD, Dieuwertje Luijks, Thorsten Zenz, MD, Anna Skowronska, PhD, Tatjana Stankovic, Mels Hoogendoorn, MD PhD, Marinus H. J. van Oers, Eric Eldering, PhD, Arnon P. Kater, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2918.
https://doi.org/10.1182/blood.V126.23.2918.2918
Published: 2015
Journal Articles

ATM Mutations in Major Stereotyped CLL Subsets: Enrichment in Subset #2 is Associated with Unfavourable Outcome

Veronika Navrkalova, PhD, Emma Young, Panagiotis Baliakas, Lenka Radova, Karla Plevova, PhD, Lesley-Ann Sutton, Larry Mansouri, Viktor Ljungstrom, Stavroula Ntoufa, Zadie Davis, Gunnar Juliusson, MD PhD, Karin E Smedby, MD PhD, Chrysoula Belessi, Panagiotis Panagiotidis, Frederic Davi, MD PhD, Anton W. Langerak, Paolo Ghia, MD PhD, Jonathan C Strefford, PhD, David G Oscier, Kostas Stamatopoulos, Sarka Pospisilova, Richard Rosenquist, Martin Trbusek, PhD
Journal: Blood
Blood (2015) 126 (23): 1712.
https://doi.org/10.1182/blood.V126.23.1712.1712
Published: 2015
Journal Articles

Single Cell Analysis Proves the Coexistence of NOTCH1 and TP53 Mutations within the Same Cancer Cells in Patients with Chronic Lymphocytic Leukemia

Barbara Kantorova, MSc., Jitka Malcikova, PhD, Kamila Brazdilova, MSc., Marek Borsky, MSc., Karla Plevova, PhD, Jana Smardova, Prof., Martin Trbusek, PhD, Yvona Brychtova, PhD, MD, Michael Doubek, Prof., MD, Jiri Mayer, Prof., MD, Sarka Pospisilova, Prof.
Journal: Blood
Blood (2015) 126 (23): 2913.
https://doi.org/10.1182/blood.V126.23.2913.2913
Published: 2015
Journal Articles

SF3B1 Mutations Frequently Occur With Both ATM Mutations and TP53 Mutations In CLL Patients

Veronika Navrkalova, MSc., Jitka Malcikova, PhD, Barbara Kantorova, MSc., Ludmila Sebejova, Karla Plevova, MSc., Marek Mraz, MD, PhD, Michael Doubek, Yvona Brychtova, MD, PhD, Jana Smardova, MD, PhD, Jiri Mayer, MD, PhD, Sarka Pospisilova, Martin Trbusek, PhD
Journal: Blood
Blood (2013) 122 (21): 2868.
https://doi.org/10.1182/blood.V122.21.2868.2868
Published: 2013
Journal Articles

Ofatumumab Added To Dexamethasone In Patients With Relapsed Or Refractory Chronic Lymphocytic Leukemia. Results From a Phase II Study Of The Czech Leukemia Study Group For Life

Michael Doubek, Yvona Brychtova, MD, PhD, Anna Panovska, MD, Jakub Trizuljak, MD, Ludmila Sebejova, Olga Stehlikova, MSc., Jana Chovancova, DVM, Jitka Malcikova, PhD, Jana Smardova, MD, PhD, Karla Plevova, MSc., Pavlina Volfova, MSc., Martin Trbusek, PhD, Marek Mraz, MD, PhD, Denisa Majercakova, MD, Petra Obrtlikova, MD, Josef Karban, MD, Lukas Smolej, MD, PhD, Michaela Lindtnerova, MD, Alexandra Oltova, MD, Eva Jelinkova, MSc., Sarka Pospisilova, Jiri Mayer, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2877.
https://doi.org/10.1182/blood.V122.21.2877.2877
Published: 2013
Journal Articles

The Fate of Chronic Lymphocytic Leukemia Patients After Failure of Fludarabine, Cyclophosphamide, and Rituximab Regimen

Anna Panovska, MD, Daniel Lysák, MD, Lukas Smolej, M.D., Ph.D., Yvona Brychtova, M.D., Ph.D., Martin Simkovic, MD, Monika Motyckova, M.D., Michaela Lindtnerova, MD, Martin Trbusek, PhD, Jitka Malcikova, Dr, PhD, Sarka Pospisilova, Prof., Jiri Mayer, M.D., PhD., Prof., Michael Doubek, M.D., PhD., Prof.
Journal: Blood
Blood (2012) 120 (21): 4603.
https://doi.org/10.1182/blood.V120.21.4603.4603
Published: 2012
Journal Articles

Microrna-34a As a Marker for Fludarabine Resistance and Impairment of p53-Pathway in Chronic Lymphocytic Leukemia

Marek Mraz, MD, PhD, Katerina Cerna, Veronika Mayerova, Katerina Musilova, Karla Plevova, Sarka Pavlova, PhD, Boris Tichy, Dr., PhD., Michael Doubek, M.D., PhD., Prof., Yvona Brychtova, M.D., Ph.D., Jitka Malcikova, Dr, PhD, Jiri Mayer, M.D., PhD., Prof., Martin Trbusek, PhD, Sarka Pospisilova, Dr, PhD
Journal: Blood
Blood (2012) 120 (21): 3883.
https://doi.org/10.1182/blood.V120.21.3883.3883
Published: 2012
Journal Articles

Defects of ATM Gene Involving Mutation Lead to Complete Elimination of ATM Function in Chronic Lymphocytic Leukemia

Veronika Navrkalova, MSc., Ludmila Sebejova, Dr., Jana Zemanova, Jana Kminkova, PharmD., Blanka Kubesova, Michael Doubek, Prof., Yvona Brychtova, M.D., Ph.D., Jana Smardova, Prof., Jiri Mayer, M.D., PhD., Prof., Sarka Pospisilova, Prof., Martin Trbusek, PhD
Journal: Blood
Blood (2012) 120 (21): 3902.
https://doi.org/10.1182/blood.V120.21.3902.3902
Published: 2012
Journal Articles

The Regulation, Targets and Clinical Relevance of Microrna Mir-650 in Chronic Lymphocytic Leukemia (CLL),

Marek Mraz, MD, Karla Plevova, Dasa Dolezalova, Katerina Stano-Kozubik, Veronika Mayerova, Katerina Cerna, Katerina Musilova, Sarka Pavlova, Dr., Boris Tichy, Dr., Jana Lochmanova, Michael Doubek, MD, PhD, Yvona Brychtova, MD, Martin Trbusek, PhD, Ales Hampl, Jiri Mayer, Sarka Pospisilova, Dr, PhD
Journal: Blood
Blood (2011) 118 (21): 3874.
https://doi.org/10.1182/blood.V118.21.3874.3874
Published: 2011
Journal Articles

Mutational Analysis of Mir-29 Family Members in Chronic Lymphocytic Leukemia

Jana Lochmanova, PharmD, Marek Mraz, MD, Veronika Navrkalova, Barbora Dvorakova, Boris Tichy, Dr, Karla Plevova, Ludmila Sebejova, Dr, Jitka Malcikova, Dr, Sarka Pavlova, PhD, Vladimir Benes, Tobias Rausch, Dr, Yvona Brychtova, MD, Michael Doubek, MD, PhD, Martin Trbusek, PhD, Jiri Mayer, Sarka Pospisilova, Dr
Journal: Blood
Blood (2011) 118 (21): 1770.
https://doi.org/10.1182/blood.V118.21.1770.1770
Published: 2011
Journal Articles

High Expression of LAG3, LPL and ZAP-70 Genes in B-CLL Strongly Correlates with Unmutated IgV H and Early Therapy Requirement.

Jana Kotaskova, MSc., Marek Mraz, MSc., Boris Tichy, Jitka Kabathova, Jitka Malcikova, MSc., Martin Trbusek, PhD., Hana Francova, MSc., Michael Doubek, MD, PhD., Yvona Brychtova, MD, Jiri Mayer, MD, PhD., Sarka Pospisilova, PhD.
Journal: Blood
Blood (2008) 112 (11): 2059.
https://doi.org/10.1182/blood.V112.11.2059.2059
Published: 2008
Journal Articles

p53 Inactivation in CLL: Pattern of 110 TP53 Mutations.

Thorsten Zenz, MD, Martin Trbusek, PhD, Jana Smardova, PhD, Sonja Häbe, Tina Denzel, Jitka Malcikova, Michael Doubek, PhD, Jiri Schwarz, MD, Hartmut Dohner, MD, Stephan Stilgenbauer, MD
Journal: Blood
Blood (2007) 110 (11): 2064.
https://doi.org/10.1182/blood.V110.11.2064.2064
Published: 2007
Journal Articles

Role of p53 Gene Mutation Type in B-CLL Prognosis.

Sarka Pospisilova, PhD, Jitka Malcikova, MSc., Jiri Damborsky, PhD., Jana Smardova, PhD., Martin Trbusek, PhD., Boris Tichy, M.D., Yvona Brychtova, M.D., Michael Doubek, M.D., PhD., Jiri Vorlicek, M.D., PhD., Jiri Mayer, M.D., PhD.
Journal: Blood
Blood (2006) 108 (11): 4324.
https://doi.org/10.1182/blood.V108.11.4324.4324
Published: 2006