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Journal Articles

RXR agonist IRX4204 induces ferroptosis in multiple myeloma via HMOX1/GPX4 axis and enhances lenalidomide efficacy

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Jian Wu, Zhibo Yan, Kimberly Burcher, Zhannan Han, Mikhail Nikiforov, Vidyasagar Vuligonda, Martin Sanders, Yubin Kang
Journal: Blood
Blood (2025) 146 (Supplement 1): 3950.
https://doi.org/10.1182/blood-2025-3950
Published: 2025
Journal Articles

RXR agonist IRX4204 enhances BCMA CAR-T-cell efficacy by suppressing ferroptosis via CHAC1 downregulation

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Jian Wu, Ying Zhou, Kimberly Burcher, Louisa Wirthlin, Jen Makepeace, Pamela Noldner, Pradyot Dash, Mikhail Nikiforov, Beth Shaz, Vidyasagar Vuligonda, Martin Sanders, Yubin Kang
Journal: Blood
Blood (2025) 146 (Supplement 1): 3947.
https://doi.org/10.1182/blood-2025-3947
Published: 2025