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Journal Articles

Anti-Human CD117 CAR T-Cells Efficiently Eliminate Hematopoietic Stem and CD117-Positive AML Cells

Renier Myburgh, PhD BSc, MSc, Jonathan Kiefer, Msc, Norman F Russkamp, Dr. MD, Alexander Simonis, Dr. MD, Surema Pfister, C. Matthias Wilk, MD, Chiara Magnani, PhD, Antonia MS Mueller, MD, Burkhard Becher, Prof. Dr., Maries van den Broek, Prof. Dr., Dario Neri, Prof. Dr., Markus G. Manz, MD

Blood (2018) 132 (Supplement 1): 4063.

https://doi.org/10.1182/blood-2018-99-118230

Published: 2018

Journal Articles

Argx-110 Targeting CD70, in Combination with Azacitidine, Shows Favorable Safety Profile and Promising Anti-Leukemia Activity in Newly Diagnosed AML Patients in an Ongoing Phase 1/2 Clinical Trial

Adrian F Ochsenbein, MD, Carsten Riether, PhD, Ulrike Bacher, Rouven Müller, MD, Sabine Höpner, PhD, Yara Banz, Magdalena Hinterbrandner, Msc, Mario Bargetzi, MD, Markus G. Manz, MD, Luc Van Rompaey, PhD, Mahan Moshir, MSc, Tim Delahaye, MSc, Domenica Gandini, MD PhD, Ellen Erzeel, Anna Hultberg, PhD, Samson Fung, MD, Hans De Haard, PhD, Nicolas Leupin, MD, Thomas Pabst, MD PhD

Blood (2018) 132 (Supplement 1): 2680.

https://doi.org/10.1182/blood-2018-99-118302

Published: 2018

Journal Articles

Graft-Vs-Host Reactivity Against the Bone Marrow Is Directed Against the Hematopoietic and Non-Hematopoietic Compartments in Mice

Hui Chyn Wong, MSc, BSc, Stephan Isringhausen, Markus G. Manz, MD, Cesar Nombela-Arrieta, Antonia MS Mueller, MD

Blood (2018) 132 (Supplement 1): 808.

https://doi.org/10.1182/blood-2018-99-116778

Published: 2018

Journal Articles

Characterizing Graft-Vs-Host Disease of the Bone Marrow Post Allogeneic Hematopoietic Cell Transplantation in Mice

Hui-Chyn Wong, PhDstudent, Stephan Isringhausen, Markus G Manz, MD, Cesar Nombela-Arrieta, Antonia Mueller, MD, Ute Suessbier, PhDcandidate

Blood (2017) 130 (Supplement 1): 3167.

https://doi.org/10.1182/blood.V130.Suppl_1.3167.3167

Published: 2017

Journal Articles

Analysis of the Hematopoietic System in Long-Term Survivors of Allogeneic Stem Cell Transplantation and Their Respective Donors

C. Matthias Wilk, MD, Steffen Boettcher, MD, Fabian Beier, MD, Tim H. Brümmendorf, MD, Markus G Manz, MD

Blood (2017) 130 (Supplement 1): 1996.

https://doi.org/10.1182/blood.V130.Suppl_1.1996.1996

Published: 2017

Journal Articles

Improvement of Relative Survival in Elderly Patients with Acute Myeloid Leukemia Emerging from Population-Based Cancer Registries in Switzerland from 2001-2013

Annatina Schnegg-Kaufmann, MD, Anita Feller, Helen Boldomero, Alicia Rovó, MD, Markus G Manz, MD, Michael Gregor, MD, Anna Efthymiou, Mario Bargetzi, MD, Urs Hess, MD, Olivier Spertini, MD, Yves Chalandon, MD PhD, Jakob R. Passweg, MDMS, Georg Stuessi, MD, Volker Arndt, MDMPH, Nicolas Bonadies, MD

Blood (2017) 130 (Supplement 1): 863.

https://doi.org/10.1182/blood.V130.Suppl_1.863.863

Published: 2017

Journal Articles

Prospective Molecular MRD Detection By NGS: A Powerful Independent Predictor for Relapse and Survival in Adults with Newly Diagnosed AML

Blood (2017) 130 (Supplement 1): LBA-5.

https://doi.org/10.1182/blood.V130.Suppl_1.LBA-5.LBA-5

Published: 2017

Journal Articles

BRAF-V600E in Peripheral Mononuclear Cells and Microglia-like Brain Cells Suggest Hematopoietic Origin of Langerhans Cell Histiocytosis-Associated Neurodegeneration

Blood (2017) 130 (Supplement 1): 2930.

https://doi.org/10.1182/blood.V130.Suppl_1.2930.2930

Published: 2017

Journal Articles

CXCL12-Abundant Reticular (CAR) Cells Are Key Regulators for a Sustained Hematopoietic Response during Chronic Inflammation

Steffen Boettcher, MD, Rahel C. Gerosa, Markus G Manz, MD

Blood (2016) 128 (22): 429.

https://doi.org/10.1182/blood.V128.22.429.429

Published: 2016

Journal Articles

The Bone Marrow Microenvironment Is a Target of Graft-Vs-Host Reactivity Following Allogeneic Hematopoietic Cell Transplantation in Mice

Hui Chyn Wong, Stephan Isringhausen, Markus G Manz, MD, César Nombela-Arrieta, PhD, Antonia MS Müller, MD

Blood (2016) 128 (22): 4539.

https://doi.org/10.1182/blood.V128.22.4539.4539

Published: 2016

Journal Articles

Effects of the Sympathicomimetic Agonist Mirabegron on Disease Course, Mutant Allele Burden, Marrow Fibrosis, and Nestin Positive Stem Cell Niche in Patients with JAK2 -Mutated Myeloproliferative Neoplasms. a Prospective Multicenter Phase II Trial SAKK 33/14

Beatrice Drexler, MD, Jakob Passweg, MD, Martin Bigler, Alexandre PA Theocharides, MD, Nathan Cantoni, MD, Peter Keller, MD, Georg Stuessi, MD, Axel Rüfer, MD, Rudolf A. Benz, MD, Geneviève Favre, MD, Alexandar Tzankov, MD, Pontus Lundberg, PhD, Andrea Fuhrer, PhD, Christine Biaggi, Markus G Manz, MD, Mario Bargetzi, MD, Simon Mendez-Ferrer, PhD, Radek C. Skoda, MD

Blood (2016) 128 (22): 3108.

https://doi.org/10.1182/blood.V128.22.3108.3108

Published: 2016

Journal Articles

BRAFV600E Transduced Human CD34 + Cells Establish Aggressive Langerhans Cell Histiocytosis in Humanized Mice

Anahita Rafiei, PhD, Yasuyuki Saito, MD PhD, Davide Soldini, MD PhD, Miriam Merad, MD PhD, Carl E. Allen, MD PhD, Markus G Manz, MD

Blood (2016) 128 (22): 2739.

https://doi.org/10.1182/blood.V128.22.2739.2739

Published: 2016

Journal Articles

Inv(16) AML Engrafts Human Cytokine Knock-in Mice

Philipp J Rauch, MD, Jana M Ellegast, MD, Larisa V Kovtonyuk, PhD, Ulrich Wagner, PhD, Rouven Müller, MD, Yasuyuki Saito, MD PhD, Nicole Wildner-Verhey van Wijk, PhD, Christine Fritz, Anahita Rafiei, PhD, Veronika Lysenko, Ewa Dudkiewicz, Davide Soldini, MD PhD, Jeroen S Goede, MD, Richard Flavell, PhD, Markus G Manz, MD

Blood (2016) 128 (22): 1078.

https://doi.org/10.1182/blood.V128.22.1078.1078

Published: 2016

Journal Articles

Mpl Expression on AML Blasts Predicts Cytopenia

Philipp J Rauch, MD, Corinne Widmer, MD, Kristin Fritsch, MS, Jana M Ellegast, MD, Jeroen S Goede, MD, Peter J M Valk, PhD, Hitoshi Takizawa, PhD, Markus G Manz, MD

Blood (2015) 126 (23): 1387.

https://doi.org/10.1182/blood.V126.23.1387.1387

Published: 2015

Journal Articles

Direct Sensing of Lipopolysaccharide Limits Hematopoietic Stem Cell Selfrenewal Via TLR4-TRIF-ROS-p38 Pathway

Hitoshi Takizawa, PhD, Yasuyuki Saito, MD PhD, Larisa V. Kovtonyuk, Kristin Frisch, Markus G. Manz, MD

Blood (2014) 124 (21): 604.

https://doi.org/10.1182/blood.V124.21.604.604

Published: 2014

Journal Articles

ΜΙSΤRG Mice Support Good-Risk AML Engraftment

Jana M. Ellegast, MD, Yasuyuki Saito, MD PhD, Richard A. Flavell, PhD, Markus G. Manz, MD

Blood (2014) 124 (21): 3808.

https://doi.org/10.1182/blood.V124.21.3808.3808

Published: 2014

Journal Articles

The Comparative Value of Hematopoietic Stem Cell Transplantation and Chemotherapy in Cytogenetically Normal AML Subclassified By NPM1 Mutation Status and FLT3 -ITD Allelic Ratio

Blood (2014) 124 (21): 323.

https://doi.org/10.1182/blood.V124.21.323.323

Published: 2014

Journal Articles

Adult Donor-Derived Human CD34 + Cell Engraftment and Hemato-Lymphoid System Development in 3rd Generation Humanized Mice

Yasuyuki Saito, MD PhD, Jana M. Ellegast, MD, Rouven Müller, MD, Richard A. Flavell, PhD, Markus G. Manz, MD

Blood (2014) 124 (21): 4378.

https://doi.org/10.1182/blood.V124.21.4378.4378

Published: 2014

Journal Articles

Next Generation Humanized Mice Support Engraftment of Myelofibrosis CD34+ Cells

Alexandre P.A. Theocharides, MD, Rouven Müller, MD, Yasuyuki Saito, MD PhD, Richard A. Flavell, PhD, Markus G. Manz, MD

Blood (2014) 124 (21): 1880.

https://doi.org/10.1182/blood.V124.21.1880.1880

Published: 2014

Journal Articles

Engraftment Of Human Polycythemia Vera CD34+ Cells In hSIRPα-Transgenic-Human-TPO-Expressing RAG2 -/- , IL2Rγ -/- Immunodeficient Mice

Rouven Müller, MD, Alexandre Theocharides, MD, Renate Looser, Radek C. Skoda, M.D., Richard A. Flavell, PhD, Markus G. Manz, MD

Blood (2013) 122 (21): 2844.

https://doi.org/10.1182/blood.V122.21.2844.2844

Published: 2013

NARROW

Anti-Human CD117 CAR T-Cells Efficiently Eliminate Hematopoietic Stem and CD117-Positive AML Cells

Argx-110 Targeting CD70, in Combination with Azacitidine, Shows Favorable Safety Profile and Promising Anti-Leukemia Activity in Newly Diagnosed AML Patients in an Ongoing Phase 1/2 Clinical Trial

Graft-Vs-Host Reactivity Against the Bone Marrow Is Directed Against the Hematopoietic and Non-Hematopoietic Compartments in Mice

Characterizing Graft-Vs-Host Disease of the Bone Marrow Post Allogeneic Hematopoietic Cell Transplantation in Mice

Analysis of the Hematopoietic System in Long-Term Survivors of Allogeneic Stem Cell Transplantation and Their Respective Donors

Improvement of Relative Survival in Elderly Patients with Acute Myeloid Leukemia Emerging from Population-Based Cancer Registries in Switzerland from 2001-2013

Prospective Molecular MRD Detection By NGS: A Powerful Independent Predictor for Relapse and Survival in Adults with Newly Diagnosed AML

BRAF-V600E in Peripheral Mononuclear Cells and Microglia-like Brain Cells Suggest Hematopoietic Origin of Langerhans Cell Histiocytosis-Associated Neurodegeneration

CXCL12-Abundant Reticular (CAR) Cells Are Key Regulators for a Sustained Hematopoietic Response during Chronic Inflammation

The Bone Marrow Microenvironment Is a Target of Graft-Vs-Host Reactivity Following Allogeneic Hematopoietic Cell Transplantation in Mice

Effects of the Sympathicomimetic Agonist Mirabegron on Disease Course, Mutant Allele Burden, Marrow Fibrosis, and Nestin Positive Stem Cell Niche in Patients with JAK2 -Mutated Myeloproliferative Neoplasms. a Prospective Multicenter Phase II Trial SAKK 33/14

BRAFV600E Transduced Human CD34 + Cells Establish Aggressive Langerhans Cell Histiocytosis in Humanized Mice

Inv(16) AML Engrafts Human Cytokine Knock-in Mice

Mpl Expression on AML Blasts Predicts Cytopenia

Direct Sensing of Lipopolysaccharide Limits Hematopoietic Stem Cell Selfrenewal Via TLR4-TRIF-ROS-p38 Pathway

ΜΙSΤRG Mice Support Good-Risk AML Engraftment

The Comparative Value of Hematopoietic Stem Cell Transplantation and Chemotherapy in Cytogenetically Normal AML Subclassified By NPM1 Mutation Status and FLT3 -ITD Allelic Ratio

Adult Donor-Derived Human CD34 + Cell Engraftment and Hemato-Lymphoid System Development in 3rd Generation Humanized Mice

Next Generation Humanized Mice Support Engraftment of Myelofibrosis CD34+ Cells

Engraftment Of Human Polycythemia Vera CD34+ Cells In hSIRPα-Transgenic-Human-TPO-Expressing RAG2 -/- , IL2Rγ -/- Immunodeficient Mice

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American Society of Hematology

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American Society of Hematology

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