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Mark T Drayson, MD PhD
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Journal Articles

Lenalidomide Maintenance Significantly Improves Outcomes Compared to Observation Irrespective of Cytogenetic Risk: Results of the Myeloma XI Trial

Graham Jackson, MDPhD, Faith E Davies, MD, Charlotte Pawlyn, BA,PhDMBBChir,MRCP,FRCPath, David Cairns, BSc, MSc, PhD, Alina Striha, MSc, Anna Hockaday, Inga Sakauskiene, John R Jones, MD, Bhuvan Kishore, MD, Mamta Garg, MD, Cathy Williams, Kamaraj Karunanithi, Jindriska Lindsay, MD, Matthew W Jenner, Gordon Cook, MD PhD, Martin F Kaiser, MD, Mark T Drayson, MD PhD, Roger G Owen, MD, Nigel H. Russell, Walter M Gregory, PhD, Gareth J. Morgan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 436.
https://doi.org/10.1182/blood.V130.Suppl_1.436.436
Published: 2017
Journal Articles

Molecular Characterisation of TP53 Aberrations in 1,777 Myeloma Trial Patients

Vallari Shah, MBBS, Amy L Sherborne, PhD, Sidra Ellis, David C. Johnson, PhD, Farzana Begum, Jack Kendall, Brian A Walker, PhD, John R Jones, MD, Charlotte Pawlyn, BA,PhDMBBChir,MRCP,FRCPath, Suvi Savola, Matthew W Jenner, Mark T Drayson, MD PhD, Roger G. Owen, MD, David Cairns, BSc, MSc, PhD, Walter M Gregory, PhD, Richard S Houlston, MD PhD, Faith E Davies, MD, Gordon Cook, MD PhD FRCP, FRCPath, Gareth J. Morgan, MD PhD, Graham Jackson, MDPhD, Martin F Kaiser, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4331.
https://doi.org/10.1182/blood.V130.Suppl_1.4331.4331
Published: 2017
Journal Articles

Tackling Early Morbidity and Mortality in Myeloma (TEAMM): Assessing the Benefit of Antibiotic Prophylaxis and Its Effect on Healthcare Associated Infections in 977 Patients

Mark T Drayson, MD PhD, Stella Bowcock, MDMA, Tim Planche, MDPhD, Gulnaz Iqbal, PhD, Jill Wood, MPH, Kerry Raynes, MSc, Guy Pratt, MD FRCP, FRCPath, Kwee Yong, PhD, Peter Hawkey, FRCPath, Helen Higgins, MSc, Janet Dunn, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 903.
https://doi.org/10.1182/blood.V130.Suppl_1.903.903
Published: 2017
Journal Articles

Minimal Residual Disease in the Maintenance Setting in Myeloma: Prognostic Significance and Impact of Lenalidomide

Ruth M de Tute, PhD FRCPath, David Cairns, BSc, MSc, PhD, Andy Rawstron, PhD, Charlotte Pawlyn, BA,PhDMBBChir,MRCP,FRCPath, Faith E. Davies, MD, John R Jones, MD, Martin F Kaiser, MD, Anna Hockaday, Alina Striha, MSc, Rowena Henderson, PhD, Gordon Cook, PhD, Nigel H. Russell, Mark T Drayson, MD PhD, Matthew W Jenner, Walter M Gregory, PhD, Graham Jackson, MDPhD, Gareth J. Morgan, MD PhD, Roger G. Owen, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 904.
https://doi.org/10.1182/blood.V130.Suppl_1.904.904
Published: 2017
Journal Articles

Assessment of Anti-Bacterial Antibodies in Multiple Myeloma Patients at Disease Presentation and in Response to Therapy: Implication for Patient Management

Ilaria Chicca, PhD, Jennifer LJ Heaney, PhD, Gulnaz Iqbal, PhD, Stella Bowcock, MDMA, Tim Planche, MDPhD, Jill Wood, MPH, Kerry Raynes, MSc, Peter Hawkey, FRCPath, Guy Pratt, MD FRCP, FRCPath, Kwee Yong, PhD, Helen Higgins, MSc, Janet Dunn, PhD, Mark T Drayson, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3036.
https://doi.org/10.1182/blood.V130.Suppl_1.3036.3036
Published: 2017
Journal Articles

Factors Predicting Poor Outcomes for Myeloma Patients at Different Ages: Results from 3894 Patients in the Myeloma XI Trial

Charlotte Pawlyn, BA,PhDMBBChir,MRCP,FRCPath, Martin F Kaiser, MD, David Cairns, BSc, MSc, PhD, Alina Striha, MSc, John R Jones, MD, Vallari Shah, MBBS, Matthew W Jenner, Mark T Drayson, MD PhD, Roger G Owen, MD, Walter M Gregory, PhD, Gordon Cook, MD PhD, Graham Jackson, MDPhD, Gareth J. Morgan, MD PhD, Faith E Davies, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3040.
https://doi.org/10.1182/blood.V130.Suppl_1.3040.3040
Published: 2017
Journal Articles

Clinical Comparison of a New Serum Free Light Chain (FLC) Assay Based on the Seralite Monoclonal Anti-FLC Antibodies with the Freelite and N-Latex FLC Assays in the Diagnosis of AL Amyloidosis

Peter Mollee, FRACP, FRCPA, MBBS, MMSc, Carel Pretorius, MBBS, Mark T Drayson, MD PhD, Jill Tate
Journal: Blood
Blood (2017) 130 (Supplement 1): 4345.
https://doi.org/10.1182/blood.V130.Suppl_1.4345.4345
Published: 2017
Journal Articles

Diagnostic Pathways of Myeloma Patients Presenting to Hospital Care and Relationship to End Organ Damage: An Analysis from the Teamm (Tackling EArly Morbidity and Mortality in Myeloma) Trial in 977 Patients

Stella Bowcock, MDMA, Catherine Atkin, MD, Gulnaz Iqbal, PhD, Tim Planche, MDPhD, Guy Pratt, MD FRCP, FRCPath, Kwee Yong, PhD, Jill Wood, MPH, Kerry Raynes, MSc, Eric Low, BSc, Helen Higgins, MSc, Janet Dunn, PhD, Mark T Drayson, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2132.
https://doi.org/10.1182/blood.V130.Suppl_1.2132.2132
Published: 2017
Journal Articles

The Mutational Landscape of Relapse in High Risk Myeloma Is Significantly Impacted By the Depth of Response but Not Maintenance Lenalidomide

John R Jones, MD, Niels Weinhold, PhD, Cody Cody Ashby, PhD, Charlotte Pawlyn, BA,PhDMBBChir,MRCP,FRCPath, Brian A Walker, PhD, Christopher P. Wardell, PhD, Lorenzo Melchor, Leo Rasche, MD, David C. Johnson, PhD, Sidra Ellis, Amy L Sherborne, PhD, Gordon Cook, MD PhD FRCP, FRCPath, Matthew W Jenner, Martin F Kaiser, MD, Walter M Gregory, PhD, Mark T Drayson, MD PhD, Roger G Owen, MD, Graham Jackson, MDPhD, Faith E. Davies, MD, Melvyn F. Greaves, PhD, Gareth J. Morgan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 396.
https://doi.org/10.1182/blood.V130.Suppl_1.396.396
Published: 2017
Journal Articles

Continuous Treatment with Lenalidomide Improves Outcomes in Newly Diagnosed Myeloma Patients Not Eligible for Autologous Stem Cell Transplant: Results of the Myeloma XI Trial

Charlotte Pawlyn, BA,PhDMBBChir,MRCP,FRCPath, Faith E. Davies, MD, David Cairns, BSc, MSc, PhD, Alina Striha, MSc, Phillip Best, Rachel Sigsworth, John R Jones, MD, Bhuvan Kishore, MD, Mamta Garg, MD, Cathy Williams, Kamaraj Karunanithi, Jindriska Lindsay, MD, Matthew W Jenner, Gordon Cook, MD PhD, Martin F Kaiser, MD, Mark T Drayson, MD PhD, Roger G Owen, MD, Nigel H. Russell, Walter M Gregory, PhD, Graham Jackson, MDPhD, Gareth J. Morgan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1854.
https://doi.org/10.1182/blood.V130.Suppl_1.1854.1854
Published: 2017
Journal Articles

Thrombotic Events in Patients with Myeloma Treated with Immunomodulatory Drugs; Results of the Myeloma XI Study

Charlotte A Bradbury, PhD MD FRCPath, FRCP, MSc, Matthew W Jenner, Alina Striha, MSc, Gordon Cook, MD PhD, Charlotte Pawlyn, BA,PhDMBBChir,MRCP,FRCPath, John R Jones, MD, David Cairns, BSc, MSc, PhD, Anna Hockaday, Andrea Paterson, Mark T Drayson, MD PhD, Roger G Owen, MD, Martin F Kaiser, MD, Walter M Gregory, PhD, Faith E. Davies, MD, Gareth J. Morgan, MD PhD, Graham H Jackson, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 553.
https://doi.org/10.1182/blood.V130.Suppl_1.553.553
Published: 2017
Journal Articles

Improving Outcomes for Patients with High-Risk Myeloma Via Prospective Trial Evidence: The Myeloma UK Nine Optimum Trial

Amy L Sherborne, PhD, Vallari Shah, MBBS, Sidra Ellis, Farzana Begum, Jack Kendall, David C Johnson, Roger G Owen, MD, Mark T Drayson, MD PhD, Louise Flanagan, Debbie Sherratt, Walter M Gregory, PhD, Graham Jackson, MDPhD, Guy Pratt, MD FRCP, FRCPath, Gordon Cook, MD PhD, Samantha Hinsley, Sarah Brown, Matthew W Jenner, Martin F Kaiser, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1767.
https://doi.org/10.1182/blood.V130.Suppl_1.1767.1767
Published: 2017
Journal Articles

Impact of Minimal Residual Disease in Transplant Ineligible Myeloma Patients: Results from the UK NCRI Myeloma XI Trial

Ruth Mary de Tute, PhD FRCPath, Andy C Rawstron, BSc, PhD, David A Cairns, MSc, PhD, Charlotte Pawlyn, MB BChir, Faith E Davies, MD, Corinne Collett, Martin F Kaiser, John R Jones, MD, Anna Waterhouse, Alina Striha, MSc, Gordon Cook, MDPhD, Matthew W Jenner, MD, Nigel H Russell, MD, Mark T Drayson, MD PhD, Walter M Gregory, PhD, Graham H Jackson, MD PhD, Gareth J Morgan, MD PhD, Roger G Owen, MD
Journal: Blood
Blood (2016) 128 (22): 245.
https://doi.org/10.1182/blood.V128.22.245.245
Published: 2016
Journal Articles

Lenalidomide Is a Highly Effective Maintenance Therapy in Myeloma Patients of All Ages; Results of the Phase III Myeloma XI Study

Graham H Jackson, MD PhD, Faith E Davies, MD, Charlotte Pawlyn, MB BChir, David A Cairns, MSc, PhD, Alina Striha, MSc, Corinne Collett, Anna Waterhouse, John R Jones, MD, Bhuvan Kishore, MBBS, MRCP, FRCPath, Mamta Garg, MD, Cathy D Williams, Kamaraj Karunanithi, MBBS, MD, Jindriska Lindsay, MD, Matthew W Jenner, MD, Gordon Cook, MDPhD, Martin F Kaiser, MD, Mark T Drayson, MD PhD, Roger G Owen, MB BCh, MD, Nigel H Russell, MD, Walter M Gregory, PhD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1143.
https://doi.org/10.1182/blood.V128.22.1143.1143
Published: 2016
Journal Articles

Primary IMiD Refractory Myeloma; Results from 3894 Patients Treated in the Phase III Myeloma XI Study

Charlotte Pawlyn, MB BChir, Faith E Davies, MD, Martin F Kaiser, MD, David A Cairns, MSc, PhD, Alina Striha, MSc, Corinne Collett, Anna Waterhouse, John R Jones, MD, Bhuvan Kishore, MBBS, MRCP, FRCPath, Mamta Garg, MD, Cathy D Williams, Kamaraj Karunanithi, MBBS, MD, Jindriska Lindsay, MD, Matthew W Jenner, MD, Gordon Cook, MD PhD, Mark T Drayson, MD PhD, Roger G Owen, MB BCh, MD, Nigel H Russell, MD, Walter M Gregory, PhD, Graham H Jackson, MD PhD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1144.
https://doi.org/10.1182/blood.V128.22.1144.1144
Published: 2016
Journal Articles

Response Adapted Induction Treatment Improves Outcomes for Myeloma Patients; Results of the Phase III Myeloma XI Study

Graham H Jackson, MD PhD, Faith E Davies, MD, Charlotte Pawlyn, MB BChir, David A Cairns, MSc, PhD, Alina Striha, MSc, Corinne Collett, Anna Waterhouse, John R Jones, MD, Bhuvan Kishore, MBBS, MRCP, FRCPath, Mamta Garg, MD, Cathy D Williams, Kamaraj Karunanithi, MBBS, MD, Jindriska Lindsay, MD, Matthew W Jenner, MD, Gordon Cook, MDPhD, Martin F Kaiser, MD, Mark T Drayson, MD PhD, Roger G Owen, MB BCh, MD, Nigel H Russell, MD, Walter M Gregory, PhD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 244.
https://doi.org/10.1182/blood.V128.22.244.244
Published: 2016
Journal Articles

DNA Methylation Profiling of Myeloma Trial Patients Reveals Specific Epigenetic Changes Associated with Outcome

David C Johnson, PhD, Dil B Begum, Sidra Ellis, Amy L Sherborne, Amy Price, Charlotte Smith, Fabio Mirabella, PhD, Karen Menezes, Scott Kimber, John R Jones, MD, Charlotte Pawlyn, MB BChir, Matthew W Jenner, MD, Richard S Houlston, MD PhD FRCP, Gordon Cook, Nigel H. Russell, V, MD, Alina Striha, MSc, Corinne Collett, Anna Waterhouse, Walter M Gregory, PhD, David A Cairns, MSc, PhD, Mark T Drayson, MD PhD, Roger G Owen, MD PhD, Faith E Davies, MD, Gareth J Morgan, MD PhD, Graham H Jackson, MD PhD, Martin F Kaiser, MD
Journal: Blood
Blood (2016) 128 (22): 804.
https://doi.org/10.1182/blood.V128.22.804.804
Published: 2016
Journal Articles

The Impact of Maintenance Lenalidomide on the Mutational Status of the Myeloma Clone at Relapse in the NCRI Myeloma XI Trial for Newly Diagnosed Multiple Myeloma Patients (NDMM)

John R Jones, MD, Niels Weinhold, PhD, Shweta S. Chavan, PhD, Charlotte Pawlyn, MB BChir, Lorenzo Melchor, PhD, David A Cairns, MSc, PhD, Dil B Begum, Charlotte Smith, Sidra Ellis, Amy Price, Amy L Sherborne, Brian A Walker, PhD, Christopher P Wardell, PhD, Gordon Cook, MD PhD, Matthew W Jenner, MD, Nigel H Russell, MD, Mark T Drayson, MD PhD, Roger G Owen, MD PhD, Faith E Davies, MD, Martin F Kaiser, MD, Graham H Jackson, MD PhD, Walter M Gregory, PhD, Mel Greaves, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4412.
https://doi.org/10.1182/blood.V128.22.4412.4412
Published: 2016
Journal Articles

Identifying Ultra-High Risk Myeloma By Integrated Molecular Genetic and Gene Expression Profiling

Amy L Sherborne, Dil B Begum, Amy Price, David C Johnson, PhD, Sidra Ellis, Charlotte Smith, Fabio Mirabella, PhD, Karen Menezes, Scott Kimber, John R Jones, MD, Charlotte Pawlyn, MB BChir, Richard S Houlston, MD PhD FRCP, Nigel H. Russell, V, MD, Matthew W Jenner, MD, Gordon Cook, Alina Striha, MSc, Corinne Collett, Anna Waterhouse, Walter M Gregory, PhD, David A Cairns, MSc, PhD, Mark T Drayson, MD PhD, Roger G Owen, MD PhD, Faith E Davies, MD, Gareth J Morgan, MD PhD, Graham H Jackson, MD PhD, Martin F Kaiser, MD
Journal: Blood
Blood (2016) 128 (22): 4407.
https://doi.org/10.1182/blood.V128.22.4407.4407
Published: 2016
Journal Articles

Specific Identification of High Risk Disease Using Molecular Profiling By Mymap (Myeloma MLPA and translocation PCR) of 1,036 Cases

Martin F Kaiser, MD, Eileen Mary Boyle, MD PhD, Brian A Walker, PhD, Dil B Begum, Paula Proszek, David C Johnson, PhD, Charlotte Pawlyn, MB BChir, John R Jones, MD, Suvi Savola, PhD, Roger G Owen, Mark T Drayson, MD PhD, David A Cairns, Gordon Cook, MD PhD, Walter M Gregory, Richard S Houlston, MDPhDFRCP, Faith E Davies, MD, Graham H Jackson, MD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2981.
https://doi.org/10.1182/blood.V126.23.2981.2981
Published: 2015