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Maria Themeli, MD, PhD
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Journal Articles

Interactions with a "Humanized" Mesenchymal Bone Marrow Stromal Niche In Vivo Modify the Patterns of Essential Genes for Myeloma Cells: Therapeutic Implications

Ryosuke Shirasaki, MD PhD, Sondra L. Downey-Kopyscinski, PhD, Ricardo De Matos Simoes, PhD, Olga Dashevsky, Sara Gandolfi, MD, Megan Bariteau, BSc, Aviad Tsherniak, PhD, Francisca Vazquez, PhD, Maria Themeli, MD PhD, Jonathan D. Licht, MD, Larry H. Boise, PhD, Richard W.J. Groen, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40.
https://doi.org/10.1182/blood-2020-143151
Published: 2020
Journal Articles

The Impact and Modulation of Microenvironment-Induced Immune Resistance Against CAR T Cell and Antibody Treatments in Multiple Myeloma

Lisa C. Holthof, MSc, Hilma J. Van Der Horst, MSc, Renée Poels, Jort T. van der Schans, MSc, Anne T. Gelderloos, MSc, Fengzhi Li, Henk Lokhorst, MD PhD, Sonja Zweegman, MD PhD, Maria Themeli, MD PhD, Niels W. C. J. Van De Donk, Richard W.J. Groen, PhD, Tuna Mutis, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 137.
https://doi.org/10.1182/blood-2019-125818
Published: 2019
Journal Articles

Potent Synergy between Combination of Chimeric Antigen Receptor (CAR) Therapy Targeting CD19 in Conjunction with Dendritic Cell (DC)/Tumor Fusion Vaccine in Hematological Malignancies

Marzia Capelletti, PhD MMSc, Jessica Liegel, MD, Maria Themeli, MD PhD, Tuna Mutis, Dina Stroopinsky, PhD, Shira Orr, PhD, Daniela Torres, Adam Morin, Gertrude Gunset, BA, Haider Ghiasuddin, Maryam Rahimian, MD, Myrna Nahas, MD, Lina Bisharat, Shufen Meng, MD, Nikhil C. Munshi, MD, Donald Kufe, MD, Jacalyn Rosenblatt, MD, Michel Sadelain, MD PhD, David E. Avigan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3227.
https://doi.org/10.1182/blood-2019-124944
Published: 2019
Journal Articles

The Combination of 41BB and CD28 Costimulatory Signals Endows Lower Affinity CAR T Cells with the Most Optimal Properties for Selective Targeting of the Tumor Associated Antigen CD38

Esther Drent, MSc, Renée Poels, BSc, Niels WCJ Van De Donk, Sonja Zweegman, MD PhD, Henk M Lokhorst, Richard WJ Groen, PhD, Tuna Mutis, PhD, Maria Themeli, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3183.
https://doi.org/10.1182/blood.V130.Suppl_1.3183.3183
Published: 2017
Journal Articles

Reducing on-Target Off-Tumor Effects of CD38-Chimeric Antigen Receptors By Affinity Optimization

Esther Drent, MSc, Maria Themeli, MD PhD, Renée Poels, Niels W.C.J. van de Donk, MD PhD, Henk M. Lokhorst, MD PhD, Tuna Mutis, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2170.
https://doi.org/10.1182/blood.V128.22.2170.2170
Published: 2016
Journal Articles

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

Fabiana Perna, MD, Ly P. Vu, Maria Themeli, MD, PhD, Ruben Hoya-Arias, PhD, Fan Liu, MD, PhD, Lan Wang, PhD, Nadia Gurvich, PhD, Todd Hricik, BS, Eirini P. Papapetrou, MD, PhD, Malcolm A.S. AS Moore, Ross L. Levine, Michel Sadelain, MD, PhD, Stephen Nimer, MD
Journal: Blood
Blood (2012) 120 (21): 2296.
https://doi.org/10.1182/blood.V120.21.2296.2296
Published: 2012