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Margaret Ashton-Key
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Journal Articles

Longitudinal Analyses of Diagnostic-Relapse Biopsies of Diffuse Large B Cell Lymphoma Reveal a Poor Risk Subset of ABC Patients Based on the Expression of a 30 Gene Panel

Findlay Bewicke-Copley, PhD MSc, BSc, Koorosh Korfi, PhD BSc, Shamzah Araf, MRCP, MBBS, PhD, Emil Arjun Kumar, BCh,BM, Thomas E C Cummin, MRCP MBBCh BSc, Margaret Ashton-Key, MD, Sharon Barrans, Suzan Van Hoppe, Cathy Burton, Mohamed Elshiekh, Simon Rule, Nicola Crosbie, Andrew James Clear, BSc, Maria Calaminici, MD PhD, David W. Scott, MBChB, PhD, Lisa M. Rimsza, MD, Menon Geetha, Chulin Sha, Michael A Bentley, Ai Nagano, PhD, Andrew Davies, MD PhD, Daniel Painter, BSc, Alexandra Smith, PhD, John G. Gribben, MD DSc, Kikkeri Naresh, David R Westhead, Jessica Okosun, MD PhD, Peter Johnson, MDFRCP, Jun Wang, PhD, Jude Fitzgibbon, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2769.
https://doi.org/10.1182/blood-2019-124352
Published: 2019
Journal Articles

Longitudinal Analyses of the Genomic, Transcriptomic, and T Cell Repertoire in Diffuse Large B Cell Lymphoma Demonstrates Changes in Signaling and Immune Recognition at Relapse

Shamzah Araf, MRCP, MBBS, Koorosh Korfi, PhD BSc, Ai Nagano, PhD, Thomas E C Cummin, MRCP MBBCh BSc, Michael Bentley, PhD, Aaron R. Thorner, PhD, Margaret Ashton-Key, MD, Maria Calaminici, MD PhD, Andrew James Clear, BSc, Andrew Davies, PhD, Sharon Barrans, Suzan Van Hoppe, Cathy Burton, Simon Rule, MD, Nicola Crosbie, Daniel Painter, BSc, Alexandra Smith, PhD, David M. Weinstock, MD, David R Westhead, Jessica Okosun, MD PhD, John G. Gribben, MDDSc FMedSci, Peter Johnson, MD FRCP, Jude Fitzgibbon, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2734.
https://doi.org/10.1182/blood.V130.Suppl_1.2734.2734
Published: 2017
Journal Articles

Regulation and Impact of BCR Induced Autophagy in Chronic Lymphocytic Leukemia

Lindsay D Smith, PhD, Laura I Karydis, PhD, Margaret Ashton-Key, MD, Jonathan C Strefford, PhD, Freda K. Stevenson, DPhil, Graham Packham, PhD, Mark Cragg, PhD, David A Tumbarello, PhD, Matthew D Blunt, PhD, Francesco Forconi, MD DM, PhD FRCPath, Andrew J Steele, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1717.
https://doi.org/10.1182/blood.V130.Suppl_1.1717.1717
Published: 2017
Journal Articles

Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK

Sergey Krysov, Andrew J. Steele, Vania Coelho, Adam Linley, Marina Sanchez Hidalgo, Matthew Carter, Kathleen N. Potter, Benjamin Kennedy, Andrew S. Duncombe, Margaret Ashton-Key, Francesco Forconi, Freda K. Stevenson, Graham Packham
Journal: Blood
Blood (2014) 124 (20): 3101–3109.
https://doi.org/10.1182/blood-2014-04-567198
Published: 2014
Includes: Supplemental data
Journal Articles

Expression of Inhibitory Fc Receptor (FcγRIIB) Is a Marker of Poor Response to Rituximab Monotherapy in Follicular Lymphoma (FL).

Chern Siang Lee, MB BS, Margaret Ashton-Key, MD FRCPath, Sergio Cogliatti, Susanne Crowe, Mark S Cragg, PhD, Shu-Fang H Schmitz, Michele Ghielmini, MD, Peter Johnson
Journal: Blood
Blood (2012) 120 (21): 2747.
https://doi.org/10.1182/blood.V120.21.2747.2747
Published: 2012
Journal Articles

Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells

Sergey Krysov, Samantha Dias, Alex Paterson, C. Ian Mockridge, Kathleen N. Potter, Kelly-Ann Smith, Margaret Ashton-Key, Freda K. Stevenson, Graham Packham
Journal: Blood
Blood (2012) 119 (1): 170–179.
https://doi.org/10.1182/blood-2011-07-370403
Published: 2012
Includes: Supplemental data
Journal Articles

Fc gamma receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy

Sean H. Lim, Andrew T. Vaughan, Margaret Ashton-Key, Emily L. Williams, Sandra V. Dixon, H. T. Claude Chan, Stephen A. Beers, Ruth R. French, Kerry L. Cox, Andrew J. Davies, Kathleen N. Potter, C. Ian Mockridge, David G. Oscier, Peter W. M. Johnson, Mark S. Cragg, Martin J. Glennie
Journal: Blood
Blood (2011) 118 (9): 2530–2540.
https://doi.org/10.1182/blood-2011-01-330357
Published: 2011
Includes: Supplemental data
Journal Articles

Primary central nervous system lymphoma: tumor-related clones exist in the blood and bone marrow with evidence for separate development

Brief Report
Katy J. McCann, Margaret Ashton-Key, KellyAnn Smith, Freda K. Stevenson, Christian H. Ottensmeier
Journal: Blood
Blood (2009) 113 (19): 4677–4680.
https://doi.org/10.1182/blood-2008-09-179366
Published: 2009
Includes: Supplemental data