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Journal Articles

Targeting the IRE1α-XBP1s Pathway to Enhance Venetoclax Effectiveness in AML

Orsola Di Martino, Mary Basse, Nancy BJ Arthur, Nishanth Gabriel, Judith Sokei, Ahmed Mahmoud, Marco Vitale, Elena Masselli, Cecilia Carubbi, Stephen Sykes, Francesca Ferraro

Blood (2024) 144 (Supplement 1): 4144.

https://doi.org/10.1182/blood-2024-210769

Published: 2024

Journal Articles

Homozygosity for -2518 G Allele Variant of MCP-1 Predisposes to Adverse Presentation and Outcome in Primary Myelofibrosis

Elena Masselli, MD, Cecilia Carubbi, PhD, Giulia Pozzi, MS, Antonio Percesepe, MD PhD, Rita Campanelli, Laura Villani, Giuliana Gobbi, PhD, Vittorio Rosti, MD, Margherita Massa, Giovanni Barosi, Marco Vitale, MD

Blood (2019) 134 (Supplement_1): 1689.

https://doi.org/10.1182/blood-2019-122750

Published: 2019

Journal Articles

Pkcε Is a Central Regulator of Mitochondrial Function and Metabolism in Acute Myeloid Leukemia

Daniela Di Marcantonio, PhD, Elena Masselli, MD, Esteban Martinez, BS, Daniela Araiza-Olivera, MD PhD, Giuliana Gobbi, PhD, Prisco Mirandola, PhD, Marco Vitale, MD, Stephen M. Sykes, PhD

Blood (2018) 132 (Supplement 1): 3926.

https://doi.org/10.1182/blood-2018-99-119758

Published: 2018

Journal Articles

Higher Monocyte Chemoattractant Protein-1 Levels in Myelofibrosis Are Sustained By the rs1024611 Single Nucleotide Polymorphism and Correlate with Disease Subtype and Severity

Elena Masselli, MD, Giulia Pozzi, MS, Cecilia Carubbi, PhD, Luca Pagliaro, MD, Elena Follini, MD, Benedetta Cambò, MD, Monica Crugnola, MD, Giuliana Gobbi, PhD, Prisco Mirandola, PhD, Franco Aversa, MD, Marco Vitale, MD

Blood (2018) 132 (Supplement 1): 1785.

https://doi.org/10.1182/blood-2018-99-111719

Published: 2018

Journal Articles

The -2518A/G (rs1026411) Regulatory Region Polymorphism of the Monocyte Chemoattractant Protein-1 (MCP-1) Is Associated with Secondary Myelofibrosis

Elena Masselli, MD, Cecilia Carubbi, PhD, Benedetta Cambò, MD, Giulia Pozzi, MS, Giuliana Gobbi, PhD, Prisco Mirandola, PhD, Elena Follini, MD, Luca Pagliaro, MD, Francesco Bonatti, PhD, Antonio Percesepe, MD PhD, Franco Aversa, MD, Marco Vitale, MD

Blood (2017) 130 (Supplement 1): 5286.

https://doi.org/10.1182/blood.V130.Suppl_1.5286.5286

Published: 2017

Journal Articles

Pkc Epsilon Regulates Mitochondrial Redox Biology to Support the Differentiation Blockade in Acute Myeloid Leukemia

Daniela Di Marcantonio, PhD, Jessica Vadaketh, Esteban Martinez, Prisco Mirandola, PhD, Giuliana Gobbi, PhD, Michael D. Milsom, PhD, Claudia Scholl, Stefan Fröhling, Marco Vitale, MD, Stephen Matthew Sykes, PhD

Blood (2015) 126 (23): 444.

https://doi.org/10.1182/blood.V126.23.444.444

Published: 2015

Journal Articles

Protein Kinase C Epsilon Inhibition Restores In-Vitro Megakaryocyte Differentiation Of Primary Myelofibrosis Hematopoietic Progenitors

Elena Masselli, MD, Prisco Mirandola, PhD, Giuliana Gobbi, PhD, Cecilia Carubbi, MS, Sabrina Bonomini, PhD, Monica Crugnola, MD, Filomena Russo, MD, Luisa Craviotto, MD, Benedetta Cambò, MD, Caterina Plenteda, MD, Elena Rossetti, MD, Cecilia Caramatti, MD, Franco Aversa, MD, Marco Vitale, MD

Blood (2013) 122 (21): 114.

https://doi.org/10.1182/blood.V122.21.114.114

Published: 2013

Journal Articles

Proplatelet generation in the mouse requires PKCε-dependent RhoA inhibition

Giuliana Gobbi, Prisco Mirandola, Cecilia Carubbi, Elena Masselli, Stephen M. Sykes, Francesca Ferraro, Antonio Nouvenne, Jonathan N. Thon, Joseph E. Italiano, Jr, Marco Vitale

Blood (2013) 122 (7): 1305–1311.

https://doi.org/10.1182/blood-2013-04-490599

Published: 2013

Includes: Supplemental data

Journal Articles

PCM1-JAK2 Fusion Product Selectively Activates MAP-Kinase Pathway and Fails to Phosphorylate JAK2 and STAT5: Implications for Therapeutic Strategies.

Elena Masselli, MD, Cristina Mecucci, Giuliana Gobbi, PhD, Cecilia Carubbi, Sabrina Bonomini, Lucia Prezioso, MD, Elena Rossetti, MD, Cecilia Caramatti, MD, Marco Vitale, MD, Franco Aversa, MD

Blood (2012) 120 (21): 2858.

https://doi.org/10.1182/blood.V120.21.2858.2858

Published: 2012

Journal Articles

Abnormal VWF modifies megakaryocytopoiesis: studies of platelets and megakaryocyte cultures from patients with von Willebrand disease type 2B

Paquita Nurden, Giuliana Gobbi, Alan Nurden, Jocelyne Enouf, Ibtissam Youlyouz-Marfak, Cecilia Carubbi, Silvia La Marca, Margherita Punzo, Luciano Baronciani, Luigi De Marco, Marco Vitale, Augusto B. Federici

Blood (2010) 115 (13): 2649–2656.

https://doi.org/10.1182/blood-2009-07-231886

Published: 2010

Journal Articles

Phorbol ester–induced PKCϵ down-modulation sensitizes AML cells to TRAIL-induced apoptosis and cell differentiation

Giuliana Gobbi, Prisco Mirandola, Cecilia Carubbi, Cristina Micheloni, Chiara Malinverno, Paolo Lunghi, Antonio Bonati, Marco Vitale

Blood (2009) 113 (13): 3080–3087.

https://doi.org/10.1182/blood-2008-03-143784

Published: 2009

Includes: Supplemental data

Journal Articles

PKCϵ controls protection against TRAIL in erythroid progenitors

Prisco Mirandola, Giuliana Gobbi, Cristina Ponti, Ivonne Sponzilli, Lucio Cocco, Marco Vitale

Blood (2006) 107 (2): 508–513.

https://doi.org/10.1182/blood-2005-07-2676

Published: 2006

Journal Articles

Activated human NK and CD8 + T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity

Prisco Mirandola, Cristina Ponti, Giuliana Gobbi, Ivonne Sponzilli, Mauro Vaccarezza, Lucio Cocco, Giorgio Zauli, Paola Secchiero, Francesco Antonio Manzoli, Marco Vitale

Blood (2004) 104 (8): 2418–2424.

https://doi.org/10.1182/blood-2004-04-1294

Published: 2004

Journal Articles

Human herpesvirus 7 induces the functional up-regulation of tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) coupled to TRAIL-R1 down-modulation in CD4 + T cells

Paola Secchiero, Prisco Mirandola, Davide Zella, Claudio Celeghini, Arianna Gonelli, Marco Vitale, Silvano Capitani, Giorgio Zauli

Blood (2001) 98 (8): 2474–2481.

https://doi.org/10.1182/blood.V98.8.2474

Published: 2001

Journal Articles

Infection of CD34 + hematopoietic progenitor cells by human herpesvirus 7 (HHV-7)

Prisco Mirandola, Paola Secchiero, Sabina Pierpaoli, Giuseppe Visani, Loris Zamai, Marco Vitale, Silvano Capitani, Giorgio Zauli

Blood (2000) 96 (1): 126–131.

https://doi.org/10.1182/blood.V96.1.126

Published: 2000

Journal Articles

TNF-related apoptosis-inducing ligand (TRAIL) as a negative regulator of normal human erythropoiesis

Loris Zamai, Paola Secchiero, Sabina Pierpaoli, Alessandra Bassini, Stefano Papa, Emad S. Alnemri, Lia Guidotti, Marco Vitale, Giorgio Zauli

Blood (2000) 95 (12): 3716–3724.

https://doi.org/10.1182/blood.V95.12.3716

Published: 2000

Journal Articles

Lineage-Restricted Expression of Protein Kinase C Isoforms in Hematopoiesis

Alessandra Bassini, Giorgio Zauli, Giovanni Migliaccio, Anna Rita Migliaccio, Massimiliano Pascuccio, Sabina Pierpaoli, Lia Guidotti, Silvano Capitani, Marco Vitale

Blood (1999) 93 (4): 1178–1188.

https://doi.org/10.1182/blood.V93.4.1178

Published: 1999

Journal Articles

Human Herpesvirus 7 Infection Induces Profound Cell Cycle Perturbations Coupled to Disregulation of cdc2 and Cyclin B and Polyploidization of CD4 + T Cells

Paola Secchiero, Lucia Bertolaso, Luca Casareto, Davide Gibellini, Marco Vitale, Kristi Bemis, Arrigo Aleotti, Silvano Capitani, Genoveffa Franchini, Robert C. Gallo, Giorgio Zauli

Blood (1998) 92 (5): 1685–1696.

https://doi.org/10.1182/blood.V92.5.1685

Published: 1998

Journal Articles

The Induction of Megakaryocyte Differentiation Is Accompanied by Selective Ser 133 Phosphorylation of the Transcription Factor CREB in Both HEL Cell Line and Primary CD34 + Cells

Giorgio Zauli, Davide Gibellini, Marco Vitale, Paola Secchiero, Claudio Celeghini, Alessandra Bassini, Sabina Pierpaoli, Marco Marchisio, Lia Guidotti, Silvano Capitani

Blood (1998) 92 (2): 472–480.

https://doi.org/10.1182/blood.V92.2.472

Published: 1998

Journal Articles

In Vitro Senescence and Apoptotic Cell Death of Human Megakaryocytes

Giorgio Zauli, Marco Vitale, Elisabetta Falcieri, Davide Gibellini, Alessandra Bassini, Claudio Celeghini, Marta Columbaro, Silvano Capitani

Blood (1997) 90 (6): 2234–2243.

https://doi.org/10.1182/blood.V90.6.2234

Published: 1997

NARROW

Targeting the IRE1α-XBP1s Pathway to Enhance Venetoclax Effectiveness in AML

Homozygosity for -2518 G Allele Variant of MCP-1 Predisposes to Adverse Presentation and Outcome in Primary Myelofibrosis

Pkcε Is a Central Regulator of Mitochondrial Function and Metabolism in Acute Myeloid Leukemia

Higher Monocyte Chemoattractant Protein-1 Levels in Myelofibrosis Are Sustained By the rs1024611 Single Nucleotide Polymorphism and Correlate with Disease Subtype and Severity

The -2518A/G (rs1026411) Regulatory Region Polymorphism of the Monocyte Chemoattractant Protein-1 (MCP-1) Is Associated with Secondary Myelofibrosis

Pkc Epsilon Regulates Mitochondrial Redox Biology to Support the Differentiation Blockade in Acute Myeloid Leukemia

Protein Kinase C Epsilon Inhibition Restores In-Vitro Megakaryocyte Differentiation Of Primary Myelofibrosis Hematopoietic Progenitors

Proplatelet generation in the mouse requires PKCε-dependent RhoA inhibition

PCM1-JAK2 Fusion Product Selectively Activates MAP-Kinase Pathway and Fails to Phosphorylate JAK2 and STAT5: Implications for Therapeutic Strategies.

Abnormal VWF modifies megakaryocytopoiesis: studies of platelets and megakaryocyte cultures from patients with von Willebrand disease type 2B

Phorbol ester–induced PKCϵ down-modulation sensitizes AML cells to TRAIL-induced apoptosis and cell differentiation

PKCϵ controls protection against TRAIL in erythroid progenitors

Activated human NK and CD8 + T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity

Human herpesvirus 7 induces the functional up-regulation of tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) coupled to TRAIL-R1 down-modulation in CD4 + T cells

Infection of CD34 + hematopoietic progenitor cells by human herpesvirus 7 (HHV-7)

TNF-related apoptosis-inducing ligand (TRAIL) as a negative regulator of normal human erythropoiesis

Lineage-Restricted Expression of Protein Kinase C Isoforms in Hematopoiesis

Human Herpesvirus 7 Infection Induces Profound Cell Cycle Perturbations Coupled to Disregulation of cdc2 and Cyclin B and Polyploidization of CD4 + T Cells

The Induction of Megakaryocyte Differentiation Is Accompanied by Selective Ser 133 Phosphorylation of the Transcription Factor CREB in Both HEL Cell Line and Primary CD34 + Cells

In Vitro Senescence and Apoptotic Cell Death of Human Megakaryocytes

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American Society of Hematology

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American Society of Hematology

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