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Journal Articles

Integrated High-Throughput Drug Profiling and CRISPR Screening Identify Novel Pathway Vulnerabilities of Leukemic Stem Cells in Chronic Myeloid Leukemia

Shady Adnan Awad, Olli Dufva, Jay Klievink, Ella Karjalainen, Aleksandr Ianevski, Paavo Pietarinen, Daehong Kim, Swapnil Potdar, Maija Wolf, Kourosh Lotfi, Tero Aittokallio, Krister Wennerberg, Kimmo Porkka, Satu Mustjoki
Journal: Blood
Blood (2022) 140 (Supplement 1): 799–800.
https://doi.org/10.1182/blood-2022-165247
Published: 2022
Journal Articles

Identification and Clinical Exploration of Individualized Targeted Therapeutic Approaches in Acute Myeloid Leukemia Patients By Integrating Drug Response and Deep Molecular Profiles

Disha Malani, MRes, Ashwini Kumar, MRes, Bhagwan Yadav, PhD, Mika Kontro, MD, Swapnil Potdar, MSc, Samuli Eldfors, MSc, Jani Saarela, Bjørn Tore Gjertsen, Riikka Karjalainen, Tero Aittokallio, Astrid Murumagi, Maija Wolf, PhD, Simon Anders, PhD, Krister Wennerberg, Caroline A Heckman, PhD, Kimmo Porkka, MD PhD, Olli Kallioniemi, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 854.
https://doi.org/10.1182/blood.V130.Suppl_1.854.854
Published: 2017
Journal Articles

Analysis of Clonal Evolution in Chemorefractory Acute Myeloid Leukemia from Diagnosis to Relapse

Naga Poojitha Ojamies, MSc, Mika Kontro, MD, Maija Wolf, PhD, Henrik Edgren, PhD, Pekka Ellonen, MSc, Sonja Lagström, MSc, Tiina Hannunen, MSc, Tea Pemovska, MSc, Henrikki Almusa, MSc, Maija Lepistö, MSc, Caroline A Heckman, PhD, Krister Wennerberg, PhD, Kimmo Porkka, MD PhD, Olli Kallioniemi, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1022.
https://doi.org/10.1182/blood.V124.21.1022.1022
Published: 2014
Journal Articles

AML Specific Targeted Drugs Identified By Drug Sensitivity and Resistance Testing: Comparison of Ex Vivo Patient Cells with in Vitro Cell Lines

Disha Malani, MSc, Astrid Murumägi, PhD, Bhagwan Yadav, MSc, Tea Pemovska, MSc, John Patrick Mpindi, MSc, Mika Kontro, MD, Tero Aittokallio, PhD, Caroline A Heckman, PhD, Kimmo Porkka, MD PhD, Krister Wennerberg, PhD, Maija Wolf, PhD, Olli Kallioniemi, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2163.
https://doi.org/10.1182/blood.V124.21.2163.2163
Published: 2014
Journal Articles

Identification Of AML Subtype-Selective Drugs By Functional Ex Vivo Drug Sensitivity and Resistance Testing and Genomic Profiling

Tea Pemovska, MSc, Mika Kontro, MD, Bhagwan Yadav, MSc, Henrik Edgren, PhD, Samuli Eldfors, MSc, Agnieszka Szwajda, MSc, Henrikki Almusa, MSc, Maxim Bespalov, PhD, Pekka Ellonen, MSc, Erkki Elonen, MD, PhD, Bjorn T Gjertsen, MD PhD, Riikka Karjalainen, MSc, Evgeny Kulesskiy, MSc, Sonja Lagström, MSc, Anna Lehto, MSc, Maija Lepistö, MSc, Tuija Lundan, PhD, Muntasir Mamun Majumder, MSc, Jesus Maria Lopez Marti, PhD, Pirkko Mattila, PhD, Astrid Murumägi, PhD, Satu Mustjoki, MD, PhD, Aino Palva, MSc, Alun Parsons, MSc, Tero Pirttinen, MD, Maria E Rämet, MD, Minna Suvela, BSc, Laura Turunen, MSc, Imre Västrik, PhD, Maija Wolf, PhD, Jonathan Knowles, PhD, Tero Aittokallio, PhD, Caroline A Heckman, PhD, Kimmo Porkka, MD, PhD, Olli Kallioniemi, MD, PhD, Krister Wennerberg, PhD
Journal: Blood
Blood (2013) 122 (21): 482.
https://doi.org/10.1182/blood.V122.21.482.482
Published: 2013
Journal Articles

Development of a Cancer Pharmacopeia-Wide Ex-Vivo Drug Sensitivity and Resistance Testing (DSRT) Platform: Identification of MEK and mTOR As Patient-Specific Molecular Drivers of Adult AML and Potent Therapeutic Combinations with Dasatinib

Mika Kontro, MD, Caroline Heckman, PhD, Evgeny Kulesskiy, MSc, Tea Pemovska, MSc, Maxim Bespalov, PhD, Samuli Eldfors, MSc, Elonen Erkki, MD, PhD, Riikka Karjalainen, MSc, Jonathan Knowles, PhD, Disha Malani, MSc, Muntasir Mamun Majumder, MSc, John Patrick Mpindi, MSc, PhD, Astrid Murumägi, PhD, Satu Mustjoki, MD, PhD, Laura Turunen, MSc, Maija Wolf, PhD, Kimmo Porkka, MD, PhD, Krister Wennerberg, PhD, Olli Kallioniemi, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2487.
https://doi.org/10.1182/blood.V118.21.2487.2487
Published: 2011
Journal Articles

Novel DNA Copy Number Changes in Hematological Malignancies: A cDNA-Based CGH Microarray Screening of CML, AML and CLL Cases without Chromosomal Imbalances in G-Banding.

Tuija Lundan, M.Sc., Anne Oikarainen, M.Sc., Lena Hafren, M.Sc., Maija Wolf, Ph.D., Erkki Elonen, M.D., Juhani Vilpo, M.D., Kimmo Porkka, M.D., Sakari Knuutila, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 4418.
https://doi.org/10.1182/blood.V104.11.4418.4418
Published: 2004