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Lucio H. Castilla, PhD
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Journal Articles

Core Binding Factor Leukemias Utilize a Physiologic Sense/Antisense Promoter Switch Employed By T-Cells

Emiel van der Kouwe, PharmD, Gerwin Heller, PhD, Akos Czibere, MD, Lucio H. Castilla, PhD, Ruud Delwel, PhD, Annalisa Di Ruscio, MD PhD, Alexander Ebralidze, PhD, Maurizio Forte, MSc, Lukas Kazianka, MD, Christoph Kornauth, Trang Le, BSc, Karin Lind, MSc, Ines Barbosa, PhD, Alexander Pichler, MD, John Pulikkan, PhD, Ann-Sofie Schmolke, MD, Heinz Sill, MD, Wolfgang R. Sperr, MD, Andreas Spittler, MD, Bon Q. Trinh, PhD, Peter Valent, MD, Katrina Vanura, PhD, Robert Welner, PhD, Johannes Zuber, PhD, Daniel G. Tenen, MD, Philipp B. Staber, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-140776
Published: 2020
Journal Articles

HIF-1α Promotes Cbfbeta-SMMHC-Induced Acute Myeloid Leukemia Development

Benedikt W. Pelzer, Anita Hollenbeck, PhD, Stefanie Weber, Bertram Opalka, PhD, Lucio H. Castilla, PhD, Ulrich Dührsen, MD, Joachim R. Göthert, MD
Journal: Blood
Blood (2016) 128 (22): 1559.
https://doi.org/10.1182/blood.V128.22.1559.1559
Published: 2016
Journal Articles

Selective Inhibition of the Leukemia Fusion Protein CBFβ-SMMHC By Small Molecule AI-10-49 in the Treatment of Inv(16) AML

John Anto Pulikkan, PhD, Anuradha Illendula, PhD, Jolanta Grembecka, Liting Xue, Roger Rajewski, Monica L. Guzman, PhD, John H. Bushweller, PhD, Lucio H. Castilla, PhD
Journal: Blood
Blood (2014) 124 (21): 390.
https://doi.org/10.1182/blood.V124.21.390.390
Published: 2014
Journal Articles

Deletion Of Core Binding Factors Runx1 and Runx2 Leads To Perturbed Hematopoiesis In Multiple Lineages

John Anto Pulikkan, PhD, Xue Liting, Rachel Gerstein, PhD, Merav Socolovsky, PhD, Lucio H. Castilla, PhD
Journal: Blood
Blood (2013) 122 (21): 46.
https://doi.org/10.1182/blood.V122.21.46.46
Published: 2013
Journal Articles

A Small Molecule Inhibitor of the CBFβ-SMMHC/RUNX Interaction Attenuates Inv(16) Leukemia in Vivo

John H. Bushweller, PhD, Anuradha Illendula, Ph.D., John Anto Pulikkan, Jolanta Grembecka, PhD, Paul Bradley, Yunpeng Zhou, Ph.D., Liting Xue, Yan Gao, Lucio H. Castilla, PhD
Journal: Blood
Blood (2012) 120 (21): 286.
https://doi.org/10.1182/blood.V120.21.286.286
Published: 2012
Journal Articles

PLAGL2 Cooperates in Leukemia Development by Direcly Inducing c-Mpl Expression.

Sean F. Landrette, BS, Lucio H. Castilla, PhD
Journal: Blood
Blood (2005) 106 (11): 744.
https://doi.org/10.1182/blood.V106.11.744.744
Published: 2005
Journal Articles

The Role of CBFβ in T Cell Development.

Ling Zhao, MD, PhD, Jennifer L. Cannons, PhD, Lucio H. Castilla, PhD, Pamela L. Schwartzberg, MD, PhD, Pu Paul Liu, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 3234.
https://doi.org/10.1182/blood.V104.11.3234.3234
Published: 2004