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Journal Articles

Evolution of Human BCR-ABL1 lymphoblastic Leukaemia-Initiating Cells.

Faiyaz Notta, PhD, Charles Mullighan, MBBS, MD, FRACP, FRCPA, MSc, Jean Wang, MD, PhD, Armando G Poeppl, Sergei Doulatov, Letha A Phillips, Jing Ma, Ph.D., Mark D. Minden, MD, PhD, James R. Downing, MD, John E. Dick, PhD

Blood (2010) 116 (21): 1023.

https://doi.org/10.1182/blood.V116.21.1023.1023

Published: 2010

Journal Articles

CREBBP Mutations In Relapsed Acute Lymphoblastic Leukemia

Charles Mullighan, MBBS, MD, FRACP, FRCPA, MSc, Jinghui Zhang, Ph.D., Lawryn H. Kasper, Ph.D., Stephanie Lerach, Ph.D., Debbie Payne-Turner, Letha A Phillips, J. Racquel Collins-Underwood, Ph.D., Susan L. Heatley, Ph.D., Jing Ma, Ph.D., Kenneth Buetow, Ph.D., Ching-Hon Pui, MD, Paul K. Brindle, Ph.D., James R. Downing, MD

Blood (2010) 116 (21): 413.

https://doi.org/10.1182/blood.V116.21.413.413

Published: 2010

Journal Articles

Integrated Genetic and Epigenetic Analysis of Childhood Acute Lymphoblastic Leukemia Reveals a Synergistic Role for Structural and Epigenetic Lesions In Determining Disease Phenotype

Maria E. Figueroa, MD, Shann-Ching Chen, Ph.D., Anna K. Andersson, PhD, Wei Liu, Ph.D., Cheng Cheng, Ph.D., Letha A Phillips, Yushan Li, James R. Downing, MD, Ari M. Melnick, Charles Mullighan, MBBS, MD, FRACP, FRCPA, MSc

Blood (2010) 116 (21): 537.

https://doi.org/10.1182/blood.V116.21.537.537

Published: 2010

Journal Articles

Rearrangement of CRLF2 in B-Progenitor and Down Syndrome Associated Acute Lymphoblastic Leukemia.

Blood (2009) 114 (22): 182.

https://doi.org/10.1182/blood.V114.22.182.182

Published: 2009

Journal Articles

Mutations in the RAS Signaling, B-Cell Development, TP53/RB1, and JAK Signaling Pathways Are Common in High Risk B-Precursor Childhood Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group (COG) High-Risk (HR) ALL TARGET Project.

Jinghui Zhang, Ph.D., Charles G. Mullighan, MBBS(Hons), MSc, MD, Richard C. Harvey, PhD, Kenneth E Buetow, Ph.D, William L. Carroll, MD, I-Ming Chen, MS, Meenakshi Devidas, PhD, Michael Edmonson, Daniela Gerhard, PhD, Ying Hu, PhD, Mignon L. Loh, MD, Letha A Phillips, BS, Gregory H Reaman, M.D., Mary V. Relling, PharmD, Malcolm Smith, MD, PhD, James R. Downing, MD, Cheryl L. Willman, MD, Stephen P Hunger, MD

Blood (2009) 114 (22): 85.

https://doi.org/10.1182/blood.V114.22.85.85

Published: 2009

Journal Articles

Identification of Novel Recurring Mutations in Relapsed Acute Lymphoblastic Leukemia.

Charles G. Mullighan, MBBS(Hons), MSc, MD, Jinghui Zhang, Ph.D., Letha A Phillips, BS, Ching-Hon Pui, MD, James R. Downing, MD

Blood (2009) 114 (22): 703.

https://doi.org/10.1182/blood.V114.22.703.703

Published: 2009

Journal Articles

Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

Charles G Mullighan, MBBS(Hons), MSc, MD, Letha A Phillips, BS, Xiaoping Su, PhD, Jing Ma, PhD, Christopher B Miller, BS, James R. Downing, MD

Blood (2008) 112 (11): 429.

https://doi.org/10.1182/blood.V112.11.429.429

Published: 2008

Journal Articles

Deletion of IKZF1 (Ikaros) Predicts Poor Outcome and Impaired Maturation in B-Progenitor Acute Lymphoblastic Leukemia

Blood (2008) 112 (11): 427.

https://doi.org/10.1182/blood.V112.11.427.427

Published: 2008

Journal Articles

Genome-Wide Analysis of Genetic Alterations in Chronic Myelogenous Leukemia.

Charles G Mullighan, MBBS(Hons), MSC, MD, Ina Radtke, PhD, Jinghui Zhang, Ph.D., Letha A. Phillips, BS, Xiaoping Su, PhD, Jing Ma, PhD, Zhongling Cai, Timothy P. Hughes, MBBS, PhD, Deborah L White, PhD, Andrew W. Roberts, MBBS, PhD, Lynda J. Campbell, MBBS, FRCPA, Sheila A. Shurtleff, James R. Downing, MD

Blood (2008) 112 (11): 1089.

https://doi.org/10.1182/blood.V112.11.1089.1089

Published: 2008

Journal Articles

Ultra-High Resolution Analysis of Genomic Alterations in High-Risk Acute Lymphoblastic Leukemia.

Charles G Mullighan, MBBS(Hons), MSc, MD, Letha A. Phillips, BS, Lesli A. Kiedrowski, Jing Ma, PhD, Richard T. Williams, MD, PhD, Sheila A. Shurtleff, Charles J. Sherr, MD, PhD, James R. Downing, MD

Blood (2008) 112 (11): 2053.

https://doi.org/10.1182/blood.V112.11.2053.2053

Published: 2008

Journal Articles

Retroviral and Chemical Mutagenesis Identifies Pax5 as a Tumor Suppressor in B-Progenitor Acute Lymphoblastic Leukemia

Jinjun Dang, PhD, Charles G Mullighan, MBBS(Hons), MSc, MD, Letha A. Phillips, BS, Perdeep Mehta, PhD, James R. Downing, MD

Blood (2008) 112 (11): 1789.

https://doi.org/10.1182/blood.V112.11.1789.1789

Published: 2008

Journal Articles

High-Resolution Genome-Wide Profiling of DNA Copy Number Abnormalities and Gene Resequencing in Pediatric Acute Myeloid Leukemia (AML).

Ina Radtke, PhD, Charles G. Mullighan, MD, PhD, Masami Ishii, MD, PhD, Jing Ma, PhD, Xiaoping Su, PhD, Salil Goorha, MD, Ramapriya Ganti, PhD, Zhongling Cai, Letha A. Phillips, Stanley B. Pounds, PhD, James Dalton, Susana C. Raimondi, PhD, Jeffrey E. Rubnitz, MD, PhD, Raul C. Ribeiro, MD, Sheila A. Shurtleff, PhD, James R. Downing, MD

Blood (2007) 110 (11): 103.

https://doi.org/10.1182/blood.V110.11.103.103

Published: 2007

Journal Articles

IKZF1 (Ikaros) Deletions Are a Hallmark of BCR-ABL1 Positive Acute Lymphoblastic Leukemia.

Charles G. Mullighan, MBBS, MD, Christopher B. Miller, BS, Letha A. Phillips, BS, James Dalton, BS, Jing Ma, PhD, Ina Radtke, MD, PhD, Deborah White, BSc(Hons), Timothy P. Hughes, MBBS, PhD, Michelle M. Le Beau, MD, PhD, Sheila A. Shurtleff, PhD, James R. Downing, MD

Blood (2007) 110 (11): 721.

https://doi.org/10.1182/blood.V110.11.721.721

Published: 2007

NARROW

Evolution of Human BCR-ABL1 lymphoblastic Leukaemia-Initiating Cells.

CREBBP Mutations In Relapsed Acute Lymphoblastic Leukemia

Integrated Genetic and Epigenetic Analysis of Childhood Acute Lymphoblastic Leukemia Reveals a Synergistic Role for Structural and Epigenetic Lesions In Determining Disease Phenotype

Rearrangement of CRLF2 in B-Progenitor and Down Syndrome Associated Acute Lymphoblastic Leukemia.

Mutations in the RAS Signaling, B-Cell Development, TP53/RB1, and JAK Signaling Pathways Are Common in High Risk B-Precursor Childhood Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group (COG) High-Risk (HR) ALL TARGET Project.

Identification of Novel Recurring Mutations in Relapsed Acute Lymphoblastic Leukemia.

Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

Deletion of IKZF1 (Ikaros) Predicts Poor Outcome and Impaired Maturation in B-Progenitor Acute Lymphoblastic Leukemia

Genome-Wide Analysis of Genetic Alterations in Chronic Myelogenous Leukemia.

Ultra-High Resolution Analysis of Genomic Alterations in High-Risk Acute Lymphoblastic Leukemia.

Retroviral and Chemical Mutagenesis Identifies Pax5 as a Tumor Suppressor in B-Progenitor Acute Lymphoblastic Leukemia

High-Resolution Genome-Wide Profiling of DNA Copy Number Abnormalities and Gene Resequencing in Pediatric Acute Myeloid Leukemia (AML).

IKZF1 (Ikaros) Deletions Are a Hallmark of BCR-ABL1 Positive Acute Lymphoblastic Leukemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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