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Leo Nicolai
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Journal Articles

Procoagulant platelet activation promotes venous thrombosis

Brief Report
Rainer Kaiser, Robin Dewender, Maité Mulkers, Julia Stermann, Dario Rossaro, Lea Di Fina, Lukas Li, Christoph Gold, Michael Schmid, Lily Kääb, Luke Eivers, Sezer Akgöl, Keyang Yue, Lisa Kammerer, Quentin Loew, Afra Anjum, Raphael Escaig, Anastassia Akhalkatsi, Lisa Laun, Jan Kranich, Thomas Brocker, Tonina T. Mueller, Angelina Krächan, Jonas Gmeiner, Kami Pekayvaz, Manuela Thienel, Steffen Massberg, Konstantin Stark, Badr Kilani, Leo Nicolai
Journal: Blood
Blood (2024) 144 (24): 2546–2553.
https://doi.org/10.1182/blood.2024025476
Published: 2024
Includes: Multimedia, Supplemental data
Journal Articles

Dissection of Single-Cell Landscapes for the Development of Chimeric Antigen Receptor T Cells in Hodgkin Lymphoma

Adrian Gottschlich, Ruth Grünmeier, Gordon Victor Hoffmann, Sayantan Nandi, Vladyslav Kavaka, Philipp Jie Müller, Jakob Jobst, Arman Öner, Rainer Kaiser, Jan Gärtig, Ignazio Piseddu, Stephanie Frenz-Wiessner, Heiko Schulz, Lea Di Fina, Maité Mulkers, Moritz Thomas, Veronika Igl, Thomas Alexander Janert, Daria Briukhovetska, Donjetë Simnica, Emanuele Carlini, Christina Tsiverioti, Marcel Trefny, Theo Lorenzini, Florian Märkl, Ruben Brabenec, Thaddäus Strzalkowski, Sophia Stock, Stefanos Michaelides, Irmela Jeremias, Johannes Christian Hellmuth, Martin Thelen, Sarah Reinke, Wolfram Klapper, Pascal Gelebart, Leo Nicolai, Carsten Marr, Eduardo Beltrán, Christoph Klein, Fanny Baran-Marszak, Paul J. Bröckelmann, Andreas Rosenwald, Michael von Bergwelt-Baildon, Stefan Endres, Sebastian Kobold
Journal: Blood
Blood (2024) 144 (Supplement 1): 4796.
https://doi.org/10.1182/blood-2024-207274
Published: 2024
Journal Articles

Procoagulant platelets promote immune evasion in triple-negative breast cancer

Johanna B. Schaubaecher, Bojan Smiljanov, Florian Haring, Katja Steiger, Zhengquan Wu, Anais Ugurluoglu, Joshua Luft, Simone Ballke, Shaan Mahameed, Vera Schneewind, Jonas Hildinger, Martin Canis, Laura A. Mittmann, Constanze Braun, Gabriele Zuchtriegel, Rainer Kaiser, Leo Nicolai, Matthias Mack, Wilko Weichert, Kirsten Lauber, Bernd Uhl, Christoph A. Reichel
Journal: Blood
Blood (2024) 144 (2): 216–226.
https://doi.org/10.1182/blood.2023022928
Published: 2024
Includes: Multimedia, Supplemental data
Journal Articles

Hemostasis without clot formation: how platelets guard the vasculature in inflammation, infection, and malignancy

Rainer Kaiser, Raphael Escaig, Leo Nicolai
Journal: Blood
Blood (2023) 142 (17): 1413–1425.
https://doi.org/10.1182/blood.2023020535
Published: 2023
Journal Articles

Mechanosensing via a GpIIb/Src/14-3-3ζ axis critically regulates platelet migration in vascular inflammation

Rainer Kaiser, Afra Anjum, Lisa Kammerer, Quentin Loew, Anastassia Akhalkatsi, Dario Rossaro, Raphael Escaig, Augustin Droste zu Senden, Ben Raude, Michael Lorenz, Christoph Gold, Kami Pekayvaz, Thomas Brocker, Jan Kranich, Julian Walter Holch, Karsten Spiekermann, Steffen Massberg, Florian Gaertner, Leo Nicolai
Journal: Blood
Blood (2023) 141 (24): 2973–2992.
https://doi.org/10.1182/blood.2022019210
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

Mechanosensing Via a Gp2b3a-Src-Axis Regulates Platelet Migration in Vitro and In Vivo

Leo Nicolai, Rainer Kaiser, Quentin Loew, Lisa Kammerer, Karsten Spiekermann, Steffen Massberg
Journal: Blood
Blood (2022) 140 (Supplement 1): 8371.
https://doi.org/10.1182/blood-2022-158320
Published: 2022
Journal Articles

Immunothrombotic Signatures of Resident and Circulating Immune Cells in Human Infective Endocarditis Revealed By Multi-Omic Profiling

Rainer Kaiser, Markus Joppich, Augustin Droste, Viktoria Knottenberg, Anastassia Akhalkatsi, Shekhar Saha, Christian Hagl, Raphael Escaig, Steffen Massberg, Rika Draenert, Konstantin Stark, Leo Nicolai, Kami Pekayvaz
Journal: Blood
Blood (2022) 140 (Supplement 1): 2591–2592.
https://doi.org/10.1182/blood-2022-163114
Published: 2022
Journal Articles

Thrombocytopenia and splenic platelet-directed immune responses after IV ChAdOx1 nCov-19 administration

Leo Nicolai, Alexander Leunig, Kami Pekayvaz, Max Esefeld, Afra Anjum, Justina Rath, Eva Riedlinger, Vincent Ehreiser, Magdalena Mader, Luke Eivers, Marie-Louise Hoffknecht, Zhe Zhang, Daniela Kugelmann, Dario Rossaro, Raphael Escaig, Rainer Kaiser, Vivien Polewka, Anna Titova, Tobias Petzold, Karsten Spiekermann, Matteo Iannacone, Thomas Thiele, Andreas Greinacher, Konstantin Stark, Steffen Massberg
Journal: Blood
Blood (2022) 140 (5): 478–490.
https://doi.org/10.1182/blood.2021014712
Published: 2022
Includes: Multimedia, Supplemental data
Journal Articles

Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI

Rainer Kaiser, Raphael Escaig, Jan Kranich, Marie-Louise Hoffknecht, Afra Anjum, Vivien Polewka, Magdalena Mader, Wenbo Hu, Larissa Belz, Christoph Gold, Anna Titova, Michael Lorenz, Kami Pekayvaz, Stefan Kääb, Florian Gaertner, Konstantin Stark, Thomas Brocker, Steffen Massberg, Leo Nicolai
Journal: Blood
Blood (2022) 140 (2): 121–139.
https://doi.org/10.1182/blood.2021014914
Published: 2022
Includes: Multimedia, Supplemental data
Journal Articles

Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps

Charlotte Marx, Julia Novotny, Danby Salbeck, Katie R. Zellner, Leo Nicolai, Kami Pekayvaz, Badr Kilani, Sven Stockhausen, Niklas Bürgener, Danny Kupka, Thomas J. Stocker, Ludwig T. Weckbach, Joachim Pircher, Markus Moser, Michael Joner, Walter Desmet, Tom Adriaenssens, Franz-Josef Neumann, Anthony H. Gerschlick, Jurrien M. ten Berg, Michael Lorenz, Konstantin Stark
Journal: Blood
Blood (2019) 134 (21): 1859–1872.
https://doi.org/10.1182/blood.2019000518
Published: 2019
Includes: Multimedia, Supplemental data