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Laura L. Swystun, PhD
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Journal Articles

VWF-FVIII Interactions Influence Hemostatic Thrombus Stability in Murine Models of Hemophilia Α and Type 2N VWD

Laura L Swystun, PhD, Courtney Dwyer, Kate Nesbitt, Kassandra Hebert, David Lillicrap, MD
Journal: Blood
Blood (2016) 128 (22): 1403.
https://doi.org/10.1182/blood.V128.22.1403.1403
Published: 2016
Journal Articles

Differential Glycosylation Between Recombinant Factor VIII Produced in Baby Hamster Kidney and Chinese Hamster Ovary Cells Confers Differences in Immunogenicity in a Humanized Hemophilia Α Mouse Model

Jesse Lai, BSc, Laura L Swystun, PhD, Dominique Cartier, Cunjie Zhang, MSc, Kate Nesbitt, James Dennis, PhD, Christine Hough, PhD, David Lillicrap, MD
Journal: Blood
Blood (2016) 128 (22): 326.
https://doi.org/10.1182/blood.V128.22.326.326
Published: 2016
Journal Articles

Characterization of Type 2N Von Willebrand Disease Mutations Using Ιn Vitro and Ιn Vivo Mouse Models

Laura L Swystun, PhD, Ilinca Georgescu, Meghan Deforest, Mia Golder, PhD, Kate Sponagle, Christine Brown, Colleen Notley, David Lillicrap, MD
Journal: Blood
Blood (2014) 124 (21): 471.
https://doi.org/10.1182/blood.V124.21.471.471
Published: 2014
Journal Articles

Clearance and Genetic Variability of Von Willebrand Factor Are Major Determinants of the Pharmacokinetic Behavior of Factor VIII Concentrates in the Treatment of Pediatric Hemophilia A

Kenichi Ogiwara, MD PhD, Laura L Swystun, PhD, Ilinca Georgescu, Christine Brown, Angie Tuttle, Shawn Tinlin, Jayne Leggo, Silvia Albánez, MSc, Manuel Carcao, MD MSc, Victor S. Blanchette, MD FRCPC, Christoph Male, MD MSC, Katharina Thom, David Lillicrap, MD
Journal: Blood
Blood (2014) 124 (21): 473.
https://doi.org/10.1182/blood.V124.21.473.473
Published: 2014
Journal Articles

Histones Induce Endothelial Von Willebrand Factor Release and Subsequent Platelet Capture in In Vitro and In Vivo Models

Alison Michels, BSc, Laura L Swystun, PhD, Silvia Albánez, MSc, Jeffrey Mewburn, Kate Sponagle, David Lillicrap, MD
Journal: Blood
Blood (2014) 124 (21): 2768.
https://doi.org/10.1182/blood.V124.21.2768.2768
Published: 2014
Journal Articles

Regulation Of Factor VIII Clearance By Mannose-Binding Lectins

Laura L. Swystun, PhD, Colleen Notley, Kate Sponagle, Paula D. James, MD, David Lillicrap
Journal: Blood
Blood (2013) 122 (21): 2340.
https://doi.org/10.1182/blood.V122.21.2340.2340
Published: 2013
Journal Articles

Platelet-Mediated Mechanical Tensile Force Influences ADAMTS13 Localization and Regulation Of Thrombus Development At The Site Of Platelet Accumulation

Yasuaki Shida, MD, PhD, Laura L. Swystun, PhD, Christine Brown, Jeff Mewburn, Kate Sponagle, Ozge Danisment, Jacob Riches, Christine Hough, PhD, David Lillicrap
Journal: Blood
Blood (2013) 122 (21): 454.
https://doi.org/10.1182/blood.V122.21.454.454
Published: 2013
Journal Articles

The Endothelial Lectin Receptor CLEC4M Internalizes Factor VIII and Von Willebrand Factor Via a Clathrin-Coated Pit-Dependent Mechanism

Laura L. Swystun, PhD, Colleen Notley, Ilinca Georgescu, Paula D. James, MD, David Lillicrap, MD
Journal: Blood
Blood (2013) 122 (21): 1091.
https://doi.org/10.1182/blood.V122.21.1091.1091
Published: 2013
Journal Articles

Genetic Variability of the CLEC4M Endothelial Lectin Receptor Modulates Binding and Internalization of Von Willebrand Factor and Contributes to Variance in Plasma VWF Levels

Laura L. Swystun, PhD, Natalia Rydz, MD, Colleen Notley, Jonathan J. Riches, Andrew D Paterson, MD, Robert R. Montgomery, MD, Paula D. James, MD, David Lillicrap, MD
Journal: Blood
Blood (2012) 120 (21): 16.
https://doi.org/10.1182/blood.V120.21.16.16
Published: 2012