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Journal Articles

Allogeneic Hematopoietic Stem Cell Transplant for B-Cell Lymphomas in the Era of Novel Cellular Therapies: Experience from a Tertiary Canadian Center

Mathias Castonguay, Jean-Sébastien Claveau, Jean Roy, Sandra Cohen, Sylvie Lachance, Imran Ahmad, Nadia M. Bambace, Lea Bernard, Jean-Sebastien Delisle, Thomas L. Kiss, Isabelle Fleury, Luigina Mollica, Denis-Claude Roy, Guy Sauvageau, Olivier Veilleux
Journal: Blood
Blood (2024) 144 (Supplement 1): 7446.
https://doi.org/10.1182/blood-2024-210718
Published: 2024
Journal Articles

Long Term Follow up of UM171 Expanded Cord Blood Transplantation Patients Does Not Reveal Any Late Toxicity

Sandra Cohen, Nadia M. Bambace, Lea Bernard, Imran Ahmad, Jean Roy, Sylvie Lachance, Jean-Sebastien Delisle, Thomas L. Kiss, Denis-Claude Roy, Olivier Veilleux, Guy Sauvageau
Journal: Blood
Blood (2024) 144 (Supplement 1): 4916.
https://doi.org/10.1182/blood-2024-194132
Published: 2024
Journal Articles

A CD33-Deleted Allograft (Trem-cel) Enables Post-Hematopoietic Cell Transplant (HCT) Maintenance Dosing of Gemtuzumab Ozogamicin (GO) with Therapeutic Levels of Drug Exposure and Low Hematologic and Hepatic Toxicity in Patients with High-Risk Acute Myeloid Leukemia (AML)

John F. DiPersio, Guenther Koehne, Nirali N. Shah, Lea Bernard, Hyung C Suh, Divya Koura, Miguel Angel Perales, Roni Tamari, Muhammad Umair Mushtaq, Joseph E. Maakaron, Michael R. Loken, Darren A Stanizzi, Melissa M. Lee-Sundlov, Sanjana Thosar, Sharon L Hyzy, Glen D Raffel, Brenda W Cooper
Journal: Blood
Blood (2024) 144 (Supplement 1): 2873.
https://doi.org/10.1182/blood-2024-205641
Published: 2024
Journal Articles

UM171 Cord Blood Transplantation for TP53 Mutated and EVI1 Rearranged Myelodysplasia/Acute Myeloid Leukemia

Sandra Cohen, Nadia M. Bambace, Lea Bernard, Imran Ahmad, Jean Roy, Sylvie Lachance, Jean-Sebastien Delisle, Thomas L. Kiss, Denis-Claude Roy, Olivier Veilleux, Guy Sauvageau
Journal: Blood
Blood (2024) 144 (Supplement 1): 1502.
https://doi.org/10.1182/blood-2024-211972
Published: 2024
Journal Articles

Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Shows Rapid Primary Engraftment with CD33-Negative Hematopoiesis in Patients with High-Risk Acute Myeloid Leukemia (AML) and Avoids Hematopoietic Toxicity during Gemtuzumab Ozogamicin (GO) Maintenance Post-Hematopoietic Cell Transplant (HCT)

John DiPersio, Brenda W Cooper, Hyung C Suh, Divya Koura, Lea Bernard, Nirali N. Shah, Roland B. Walter, Miguel-Angel Perales, Markus Mapara, Roni Tamari, Michael R. Loken, Kyle Breitschwerdt, Sritama Nath, Glen D Raffel, Guenther Koehne
Journal: Blood
Blood (2023) 142 (Supplement 1): 483.
https://doi.org/10.1182/blood-2023-190037
Published: 2023
Journal Articles

Infusion of UM171-Expanded Cord Blood Led to Excellent Survival in Patients with High-Risk Leukemias: Results from Two Independent Phase II Studies

Filippo Milano, Guy Sauvageau, Gabrielle Thauvette, Nadia M. Bambace, Lea Bernard, Imran Ahmad, Jean Roy, Laura C Roberts, Laurel Thur, Jenna B Pedersen, Ann Dahlberg, Sandra Cohen
Journal: Blood
Blood (2023) 142 (Supplement 1): 1040.
https://doi.org/10.1182/blood-2023-187446
Published: 2023
Journal Articles

The EBMT Disease Risk Stratification System (DRSS) Allows Prediction of Relapse after Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome

Yasmine Kadri, Michelle Phan, Nadia Bambace, Léa Bernard, Sandra Cohen, Jean-Sébastien Delisle, Thomas L. Kiss, Sylvia Lachance, Denis-Claude Roy, Jean Roy, Guy Sauvageau, Olivier Veilleux, Imran Ahmad
Journal: Blood
Blood (2022) 140 (Supplement 1): 7759–7760.
https://doi.org/10.1182/blood-2022-157107
Published: 2022
Journal Articles

Improved Outcomes of UM171-Expanded Cord Blood Transplantation Compared with Other Graft Sources: Real World Evidence

Sandra Cohen, Nadia M. Bambace, Imran Ahmad, Linda J. Burns, Jean Roy, Silvy Lachance, Léa Bernard, Jean-Sébastien Delisle, Denis-Claude Roy, Thomas L. Kiss, Olivier Veilleux, Mei-Jie Zhang, Xiao-Ying Tang, Guy Sauvageau
Journal: Blood
Blood (2022) 140 (Supplement 1): 1610–1612.
https://doi.org/10.1182/blood-2022-160417
Published: 2022
Journal Articles

Trial in Progress: A First-in-Human Phase 1/2 Study of Hematopoietic Stem Cell Transplantation (HCT) with VOR33 (CD33-Deleted Allograft) Followed By Treatment with Gemtuzumab Ozogamicin (GO) in Patients with CD33+ Acute Myeloid Leukemia (AML) Who Are at High-Risk of Post-HCT Relapse

Brenda W. Cooper, Hyung C. Suh, Divya Koura, Guenther Koehne, Christina Cho, Nadia M. Bambace, Léa Bernard, Nirali N. Shah, Roland B. Walter, John F. DiPersio, Sritama Nath, Melissa M. Lee-Sundlov, Ali Lacy, Darren Stanizzi, Karen Kuhn, Jennifer S. Whangbo, Christopher Slapak, Glen D. Raffel
Journal: Blood
Blood (2022) 140 (Supplement 1): 12973–12975.
https://doi.org/10.1182/blood-2022-165289
Published: 2022
Journal Articles

Ex Vivo Generation and Infusion of Anti-Minor Histocompatibility Antigen Expanded T Cells for Patients Who Relapse after Allogeneic HLA-Matched Stem Cell Transplantation

Denis-Claude Roy, Jean-Sébastien Delisle, Imran Ahmad, Brian Leber, Félix Couture, Stephanie Thiant, Natasha Kekre, Radia Sidi Boumedine, Cédric Carli, Ann Brasey, Nadia M. Bambace, Léa Bernard, Sandra Cohen, Thomas L. Kiss, Jean Roy, Guy Sauvageau, Olivier Veilleux, Claude Perreault, Lambert Busque, Silvy Lachance
Journal: Blood
Blood (2022) 140 (Supplement 1): 1601–1603.
https://doi.org/10.1182/blood-2022-170147
Published: 2022
Journal Articles

Efficacy, Toxicity and Cost of Venetoclax-Based Combinations for the Treatment of Acute Myeloid Leukemia: Real-World Evidence from a Canadian Academic Center

Philippe Bouchard, Annie Brisebois-Boyer, Anne Beaudry, Jean-Francois Berthiaume, Nadia M. Bambace, Léa Bernard, Josee Hebert, Julie Bergeron
Journal: Blood
Blood (2021) 138 (Supplement 1): 1253.
https://doi.org/10.1182/blood-2021-149967
Published: 2021
Journal Articles

UM171-Expanded Cord Blood Transplants Support Robust T-Cell Reconstitution with Low Rates of Severe Infections

Maude Dumont-Lagacé, Qi Li, Mégane Tanguay, MD, Jalila Chagraoui, PhD, Tibila Kientega, Guillaume Cardin, Ann Brasey, PhD, Assya Trofimov, MSc, Cédric Carli, PhD, Imran Ahmad, MD, Nadia M. Bambace, MD, Léa Bernard, MD, Thomas L. Kiss, MD, Jean Roy, MD, Denis-Claude Roy, MD, Sébastien Lemieux, PhD, Claude Perreault, MD, Francis Rodier, PhD, Simon Frédéric Dufresne, MD FRCP, Lambert Busque, MD, Silvy Lachance, MD FRCP, Guy Sauvageau, MDPhD, Sandra Cohen, MD FRCP(C), Jean-Sébastien Delisle, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 36–37.
https://doi.org/10.1182/blood-2020-139598
Published: 2020
Journal Articles

UM171 Modified Cord Blood Achieves Excellent Survival and Disease Control after 2 Years of Follow-up in High and Very High Risk Malignancies

Sandra Cohen, MD FRCP(C), Jean Roy, MD, Jean-Sébastien Delisle, MD PhD, Nadia M. Bambace, MD, Imran Ahmad, MD, Silvy Lachance, MD FRCP, Léa Bernard, MD, Frederic Barabe, MD, Thomas L. Kiss, MD, Lambert Busque, MD, Denis-Claude Roy, MD, Filippo Milano, MD PhD, Guy Sauvageau, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3245.
https://doi.org/10.1182/blood-2019-121698
Published: 2019
Journal Articles

Single UM171 Expanded Cord Blood Permits Transplantation of Better HLA Matched Cords with Excellent Gvhd Relapse Free Survival

Sandra Cohen, MD FRCP(C), Jean Roy, MD, Silvy Lachance, MD FRCP, Anne Marinier, PhD, Jean-Sébastien Delisle, MD PhD, Denis-Claude Roy, MD, Lambert Busque, MD, Imran Ahmad, MD MPH, Nadia M. Bambace, MD, Frederic Barabe, MD, Léa Bernard, MD, Thomas L. Kiss, MD, Philippe Bouchard, BPharm, Pierre Caudrelier, MD, Fannie Larochelle, Sébastien Lemieux, PhD, Mégane Tanguay, Jalila Chagraoui, PhD, Peter W. Zandstra, PhD, Guy Sauvageau, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4658.
https://doi.org/10.1182/blood-2018-99-110188
Published: 2018
Journal Articles

Minimal Residual Disease Evaluation Using 8-Color Flow Cytometry Predicts Risk of Relapse in High-Risk and/or Young Myeloma Patients Who Receive Bortezomib Consolidation after Frontline Tandem Transplantation

Richard Leblanc, MD FRCPC, Imran Ahmad, MD MPH, Rafik Terra, PhD, Séverine Landais, PhD, Céline Nkoue, MD, Michael Sebag, MD PhD, Émilie Lemieux Blanchard, MD FRCPC, Nadia M. Bambace, MD, Léa Bernard, MD, Sandra Cohen, MD FRCP(C), Jean-Sébastien Delisle, MD PhD, Thomas L. Kiss, MD, Silvy Lachance, MD FRCP, Denis-Claude Roy, MD, Guy Sauvageau, MD, PhD, Jean Roy, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4666.
https://doi.org/10.1182/blood-2018-99-112313
Published: 2018
Journal Articles

Impact of Carmustine (BCNU) Substitution for Bendamustine in the Conditioning Regimen Prior to Autologous Hematopoietic Cell Transplantation for the Treatment of Lymphoma

Josie-Anne Boisjoly, MD, Philippe Bouchard, BPharm, Sandra Cohen, MD FRCP(C), Imran Ahmad, MD, Nadia M. Bambace, MD, Léa Bernard, MD, Jean-Sébastien Delisle, MD PhD, Thomas L Kiss, MD, Denis-Claude Roy, MD, Guy Sauvageau, MD, PhD, Jean Roy, MD, Silvy Lachance, MDFRCPC
Journal: Blood
Blood (2017) 130 (Supplement 1): 2022.
https://doi.org/10.1182/blood.V130.Suppl_1.2022.2022
Published: 2017
Journal Articles

Bortezomib Consolidation after Nonmyeloablative Allogeneic Transplant Is Safe and Leads to a High Incidence of Immunophenotypic Complete Response in High-Risk or Young Myeloma Patients

Richard LeBlanc, MDFRCPC, Imran Ahmad, MD M.Sc., Rafik Terra, PhD, Séverine Landais, PhD, Michael Sebag, MD PhD, Emilie Lemieux-Blanchard, MD, Nadia M. Bambace, MD, Léa Bernard, MD, Sandra Cohen, MD, Jean-Sébastien Delisle, MD PhD, Thomas Kiss, MD, Silvy Lachance, MDFRCPC, Denis-Claude Roy, MD, Guy Sauvageau, MD PhD, Jean Roy, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4556.
https://doi.org/10.1182/blood.V130.Suppl_1.4556.4556
Published: 2017
Journal Articles

Single UM171 Expanded Cord Blood Transplant Is Feasible, Safe, and Permits Transplantation of Better HLA Matched Cords with Very Low Transplant Related Mortality

Sandra Cohen, MD, Jean Roy, MD, Silvy Lachance, MDFRCPC, Anne Marinier, PhD, Denis-Claude Roy, MD, Jean-Sébastien Delisle, MD PhD, Lambert Busque, MD, Pierre Caudrelier, MD, Fannie Larochelle, Philippe Bouchard, BPharm, Jean Roy, MD, Nadia M. Bambace, MD, Léa Bernard, MD, Thomas L Kiss, MD, Sébastien Lemieux, PhD, Peter W. Zandstra, PhD, Guy Sauvageau, MD, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 658.
https://doi.org/10.1182/blood.V130.Suppl_1.658.658
Published: 2017
Journal Articles

Bortezomib Consolidation after Nonmyeloablative Allogeneic Stem Cell Transplantation Leads to a High Incidence of Immunophenotypic Complete Response in Young and/or High-Risk Multiple Myeloma Patients

Richard LeBlanc, MD, Imran Ahmad, MD, Rafik Terra, PhD, Séverine Landais, PhD, Michael Sebag, MD PhD, Emilie Lemieux-Blanchard, MD, Nadia M. Bambace, MD, Lea Bernard, MD, Sandra Cohen, MD, Jean-Sebastien Delisle, MD PhD, Thomas Kiss, MD, Silvy Lachance, MD, Denis-Claude Roy, MD, Guy Sauvageau, MD PhD, Jean Roy, MD
Journal: Blood
Blood (2016) 128 (22): 2306.
https://doi.org/10.1182/blood.V128.22.2306.2306
Published: 2016
Journal Articles

Evaluation of the Impact of Hematopoietic Stem Cell Transplant on the Quality of Life of Elderly Patients Treated for Lymphoma

Christopher Lemieux, MD, Nadia M. Bambace, MD, Jean Roy, MD, Sandra Cohen, MD, Imran Ahmad, MD, Lea Bernard, MD, Jean-Sebastien Delisle, MD PhD, Thomas Kiss, MD, Silvy Lachance, MD
Journal: Blood
Blood (2016) 128 (22): 4788.
https://doi.org/10.1182/blood.V128.22.4788.4788
Published: 2016