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Kyle R Crassini
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Journal Articles

Optimizing Immunoglobulin Replacement Therapy for Patients with B-Cell Malignancies and Hypogammaglobulinemia: The Investigator-Initiated, International, Randomized Phase II/III Rational Platform Trial, and the Rationalise (STOP IgRT) Domain

Erica M. Wood, Khai Li Chai, John Reynolds, Jennifer Griffiths, Brendan Beaton, Jeannie Callum, Kyle R Crassini, Philip J Crispin, Laura Fanning, Michael Gilbertson, Andrew P Grigg, Eliza A Hawkes, C. Orla Morrissey, Stephen P Mulligan, Stephen S. Opat, David L Paterson, Dennis Petrie, Jason A Roberts, Elizabeth G Ryan, Andrew Spencer, Simon J Stanworth, Le Thi Phuong Thao, Judith Trotman, Neil A Waters, Robert Weinkove, Zoe K McQuilten
Journal: Blood
Blood (2023) 142 (Supplement 1): 1295.
https://doi.org/10.1182/blood-2023-181541
Published: 2023
Journal Articles

Venetoclax Is Synergistic with Idelalisib or MK2206 Against Primary CLL Cells in an in Vitro Model of the Microenvironment

Yandong Shen, BMedSc (Hon) PhD, Kyle R Crassini, MBBS,BSc, Narjis Fatima, BSMedTech,MPhil, Richard Christopherson, PhDEmeritus Professor, Stephen P. Mulligan, PhDFRACP,FRCPA,MBBS, Oliver Giles Best, PhDBSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 5443.
https://doi.org/10.1182/blood-2019-130082
Published: 2019
Journal Articles

TR57, an Inhibitor of the Integrated Stress Response, Is Synergistic with Venetoclax Against CLL Cells, Independent of Their TP53 Status

Narjis Fatima, BSMedTech,MPhil, Yandong Shen, BMedSc (Hon) PhD, Kyle R Crassini, MBBS,BSc, Edwin Iwanowicz, PhD, Richard Christopherson, PhDEmeritus Professor, Giles Best, BSc, PhD, Stephen P. Mulligan, PhDFRACP,FRCPA,MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 1735.
https://doi.org/10.1182/blood-2019-132160
Published: 2019
Journal Articles

mRNA Profiling of CLL Cells Derived from the Blood, Bone Marrow and Lymph Node

Kyle R Crassini, MBBS, BSc, Yandong Shen, BMedSc (Hon), William S. Stevenson, MBBS, PhD, Stephen P. Mulligan, PhD, FRACP, FRCPA, MBBS, Oliver Giles Best, PhD BSc, Richard Christopherson, PhD Emeritus Professor
Journal: Blood
Blood (2018) 132 (Supplement 1): 1850.
https://doi.org/10.1182/blood-2018-99-118264
Published: 2018
Journal Articles

The Dual PI3/PIM-Kinase Inhibitor, Ibl-202, Is Highly Synergistic with Venetoclax Against CLL Cells, and TP53 -Knock-out Cells, and Under Conditions That Mimic the Tumor Microenvironment

Yandong Shen, BMedSc (Hon), Kyle R Crassini, MBBS, BSc, Michael E O'Dwyer, MD, Michael Francis O'Neill, PhD BA, Richard Christopherson, PhD Emeritus Professor, Stephen P. Mulligan, PhD FRACP, FRCPA, MBBS, Oliver Giles Best, PhD BSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 1870.
https://doi.org/10.1182/blood-2018-99-115574
Published: 2018
Journal Articles

ONC-212 (I-39), a Novel Inhibitor of the UPR, Is Cytotoxic and Cytostatic Against CLL Cells Under in Vitro Conditions That Mimic the Tumor Microenvironment

Narjis Rizwan, BSMedTech, MPhil, PhD, Yandong Shen, BMedSc (Hon), Edwin Iwanowicz, PhD, Stephen P. Mulligan, PhD FRACP, FRCPA, MBBS, Kyle R Crassini, MBBS, BSc, Richard Christopherson, PhD Emeritus Professor, Oliver Giles Best, PhD BSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 3145.
https://doi.org/10.1182/blood-2018-99-115555
Published: 2018
Journal Articles

Inhibition of AKT By MK2206 but Not PI3-Kinase δ By Idelalisib Is Effective Against CLL Cells in an In Vitro Model of the Hypoxic Microenvironment

Yandong Shen, BMedSc (Hon), Kyle R Crassini, MBBS,BE,BSc, Stephen Mulligan, PhDFRACP,FRCPA,MBBS, Richard Christopherson, PhDEmeritus Professor, Oliver Giles Best, PhDBSc
Journal: Blood
Blood (2017) 130 (Supplement 1): 5340.
https://doi.org/10.1182/blood.V130.Suppl_1.5340.5340
Published: 2017
Journal Articles

Deficiencies in Immunoglobulin Classes and Immunoglobulin G Subclasses Are Associated with Shorter Treatment Free Survival and Overall Survival in CLL

Kyle R Crassini, MBBS,BE,BSc, Eva Zhang, MBBS, Shalini Balendran, MBBS, Jane Freeman, BA,FRACP,FRCPA,MBBS,MPhil,MSc, Oliver Giles Best, PhDBSc, Cecily Forsyth, FRACP, FRCPA, MBBS, Naomi Mackinlay, Ping Han, MDPhD, William S. Stevenson, MBBS,PhD, Stephen Mulligan, PhDFRACP,FRCPA,MBBS
Journal: Blood
Blood (2017) 130 (Supplement 1): 5321.
https://doi.org/10.1182/blood.V130.Suppl_1.5321.5321
Published: 2017
Journal Articles

Analysis of mRNA Expression in Peripheral, Bone Marrow and Lymph Node Dervied CLL Cells Using the Nanosting Ncounter Platform

Kyle R Crassini, MBBS,BE,BSc, Yandong Shen, BMedSc (Hon), Richard Christopherson, PhDEmeritus Professor, William S. Stevenson, MBBS,PhD, Stephen Mulligan, PhDFRACP,FRCPA,MBBS, Oliver Giles Best, PhDBSc
Journal: Blood
Blood (2017) 130 (Supplement 1): 4279.
https://doi.org/10.1182/blood.V130.Suppl_1.4279.4279
Published: 2017