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Katrina J Ashworth
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Journal Articles

LRRC8 complexes are ATP release channels regulating platelet activation and arterial thrombosis

Open Access
John David Tranter, Ryan Takayuki Mikami, Ashutosh Kumar, Gavriel Brown, Tarek Mohamed Abd El-Aziz, Yonghui Zhao, Prakash Arullampalam, Katrina J Ashworth, Vishwanath Jha, Nihil Abraham, Chloe Meyer, Abigail Ajanel Gomez, Litao Xie, Yongmei Feng, Juan Hong, Haixia Zhang, Tripti Kumari, Adam Balutowski, Alice Liu, David Bark, Vinayak K Nair, Nina M Lasky, Nathan O Stitziel, Daniel J Lerner, Robert A Campbell, Jorge Di Paola, Jaehyung Cho, Rajan Sah
Journal: Blood
Blood blood.2024026667.
https://doi.org/10.1182/blood.2024026667
Published: 2025
Includes: Multimedia, Supplemental data
Journal Articles

Single-cell transcriptional analysis of human endothelial colony-forming cells from patients with low VWF levels

Free
Christopher J. Ng, Alice Liu, Sujatha Venkataraman, Katrina J. Ashworth, Christopher D. Baker, Rebecca O’Rourke, Rajeev Vibhakar, Kenneth L. Jones, Jorge Di Paola
Journal: Blood
Blood (2022) 139 (14): 2240–2251.
https://doi.org/10.1182/blood.2021010683
Published: 2022
Includes: Supplemental data
Journal Articles

Single Cell RNA Sequencing of Blood Outgrowth Endothelial Cells from Patients with Low Von Willebrand Factor Reveal Multiple Novel Signaling Pathways

Free
Christopher J. Ng, MD, Alice Liu, BS, Katrina J. Ashworth, MS, Kenneth L. Jones, PhD, Jorge Di Paola, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 982.
https://doi.org/10.1182/blood-2018-99-116694
Published: 2018
Journal Articles

Epigenetic Profiles of Primary Endothelial Cells from Patients with Low VWF Levels

Free
Christopher J. Ng, MD, Alice Liu, BS, Katrina J. Ashworth, MS, Kenneth L. Jones, PhD, Jorge Di Paola, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 983.
https://doi.org/10.1182/blood-2018-99-116719
Published: 2018
Journal Articles

TNF-α Driven Inflammation and Mitochondrial Dysfunction Characterize the Platelet Hyperreactivity of Aging and Myeloproliferative Neoplasms (MPN)

Free
Pavel Davizon-Castillo, MD, Brandon McMahon, MD, Sonia Aguila, PhD, Kenneth L. Jones, PhD, George D Trahan, MS, Katrina J. Ashworth, MS, David Bark, PhD, Robert A. Campbell, PhD, Kelly Higa, MS, Lauren Christine Shih, BA, Natalie Saunders, MD, James DeGregori, Matthew T. Rondina, MD, Jorge Di Paola, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1134.
https://doi.org/10.1182/blood-2018-99-119620
Published: 2018
Journal Articles

Endothelial Colony Forming Cells from Individuals with Low VWF Levels Demonstrate Impairment in Stimulated VWF Release

Free
Christopher J. Ng, MD, Katrina J. Ashworth, MS, Marilyn J Manco-Johnson, MD, Christopher Baker, MD, Jorge Di Paola, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 21.
https://doi.org/10.1182/blood.V130.Suppl_1.21.21
Published: 2017
Journal Articles

A CRISPR-Cas9 Generated Etv6 mutant Mouse Exhibits Decreased Platelet Counts and Functional Platelet Defects

Free
Leila Noetzli, BS, Jesse W Rowley, PhD, Pavel Davizon-Castillo, MD, Greg Kirkpatrick, Katrina J. Ashworth, MS, Sonia Aguila, PhD, Christopher C. Porter, MD, Eric Martin Pietras, PhD, Andrew S. Weyrich, PhD, Jorge Di Paola, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1035.
https://doi.org/10.1182/blood.V130.Suppl_1.1035.1035
Published: 2017
Journal Articles

Aging-Associated Inflammation Due to Elevated Levels of TNF-α Increases Activation of the Integrin αIIbβ3 and the Procoagulant Potential of Platelets

Free
Pavel Davizon-Castillo, MD, Ken L. Jones, PhD, Sonia Aguila, PhD, David Bark, PhD, Katrina J. Ashworth, MS, Kelly Higa, MS, Eric Martin Pietras, PhD, Robert A. Campbell, PhD, Lauren Christine Shih, BA, Natalie Saunders, MD, James DeGregori, Matthew T. Rondina, MD, Jorge Di Paola, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 292.
https://doi.org/10.1182/blood.V130.Suppl_1.292.292
Published: 2017
Journal Articles

The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi

Free
Mehran Ghasemzadeh, Zane S. Kaplan, Imala Alwis, Simone M. Schoenwaelder, Katrina J. Ashworth, Erik Westein, Ehteramolsadat Hosseini, Hatem H. Salem, Robyn Slattery, Shaun R. McColl, Michael J. Hickey, Zaverio M. Ruggeri, Yuping Yuan, Shaun P. Jackson
Journal: Blood
Blood (2013) 121 (22): 4555–4566.
https://doi.org/10.1182/blood-2012-09-459636
Published: 2013
Includes: Multimedia, Supplemental data
Journal Articles

High shear–dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction

Free
Susan L. Cranmer, Katrina J. Ashworth, Yu Yao, Michael C. Berndt, Zaverio M. Ruggeri, Robert K. Andrews, Shaun P. Jackson
Journal: Blood
Blood (2011) 117 (9): 2718–2727.
https://doi.org/10.1182/blood-2010-07-296194
Published: 2011
Includes: Multimedia, Supplemental data