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Journal Articles

Induced PD-1 Expression on Bone Marrow CD34+ Cells from MDS Patients Treated with 5-Azacitadine in Combination with Nivolumab and/or Ipilimumab

Hui Yang, PhDMD, Zhihong Fang, Karen Clise-Dwyer, PhD, Kathryn Ruisaard, Simona Colla, PhD, Irene Ganan-Gomez, PhD, Guillermo Montalban-Bravo, MD, Kelly Soltysiak, Naval G. Daver, MD, Elias J. Jabbour, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2018) 132 (Supplement 1): 1807.

https://doi.org/10.1182/blood-2018-99-119278

Published: 2018

Journal Articles

Identification of Myeloperoxidase As a Leukemia-Associated Antigen and Therapeutic Target for Acute Myeloid Leukemia

Eran Tallis, Sijie Lu, PhD, Xiaoling Ding, Dan Li, PhD, Kathryn Ruisaard, M. James You, MD PhD, Lisa St. John, Gheath Alatrash, DO, PhD, Qing Ma, PhD, Jeffrey J. Molldrem, MD

Blood (2017) 130 (Supplement 1): 4460.

https://doi.org/10.1182/blood.V130.Suppl_1.4460.4460

Published: 2017

Journal Articles

Inhibition of T Cell Proliferation By Granulocyte Membrane-Associated Proteinase 3 Is Reversed By Blocking the Interaction of Calreticulin with LRP on T Cells

Tian-Hui Yang, PhD, Lisa S. St. John, PhD, Karen Clise-Dwyer, PhD, Kathryn Ruisaard, MS, Gheath Alatrash, DO, PhD, Jeffrey J. Molldrem, MD

Blood (2014) 124 (21): 4110.

https://doi.org/10.1182/blood.V124.21.4110.4110

Published: 2014

Journal Articles

Membrane-Associated Proteinase 3 On Granulocytes and Myeloid Leukemia Mediates Reversible Inhibition of T Cell Proliferation Associated with Altered ZAP70 and ERK Signaling

Tian-Hui Yang, MD, PhD, Karen Clise-Dwyer, PhD, S Lisa, St. John, PhD, Gheath Alatrash, DO, PhD, Kathryn Ruisaard, MS, Sijie Lu, PhD, Jeffrey J. Molldrem, MD

Blood (2012) 120 (21): 1031.

https://doi.org/10.1182/blood.V120.21.1031.1031

Published: 2012

Journal Articles

RNA-Seq Expression Profiling of AML Stem Cells Reveals Differential Expression of Lineage Differentiation Markers and Novel Splice Variants.

Benjamin G Vincent, MD, Darshan Singh, MS, Michael Wu, PhD, Sally A. Hunsucker, PhD, Gheath Alatrash, DO, PhD, Kathryn Ruisaard, MS, Pariya Sukhumalchandra, BS, Karen Clise-Dwyer, PhD, Jonathan S Serody, MD, Jan F Prins, PhD, Jeffrey J. Molldrem, M.D., Paul M. Armistead, MD, PhD

Blood (2012) 120 (21): 2502.

https://doi.org/10.1182/blood.V120.21.2502.2502

Published: 2012

Journal Articles

Multiple Myeloma Cross-Presents Neutrophil Elastase and Proteinase 3 and Becomes Susceptible to PR1-Targeting Immunotherapy

Gheath Alatrash, DO, PhD, Pariya Sukhumalchandra, BS, Mao Zhang, MPH, Anna Sergeeva, PhD, Haroon Jakher, BS, Jinsheng Weng, Ph.D, Lisa S St. John, PhD, Kathryn Ruisaard, BS, Karen Clise-Dwyer, PhD, Sijie Lu, PhD, Jeffrey J. Molldrem, MD

Blood (2012) 120 (21): 4973.

https://doi.org/10.1182/blood.V120.21.4973.4973

Published: 2012

Journal Articles

Treatment with 8F4, An Anti-PR1/HLA-A2 T Cell Receptor-Like Antibody, Reduces Established Acute Myeloid Leukemia and Eliminates Leukemia Stem Cells in Mice

Anna Sergeeva, PhD, Hong He, MD, PhD, Kathryn Ruisaard, MS, Karen Clise-Dwyer, PhD, Lisa S St. John, PhD, Rebecca Patenia, Pariya Sukhumalchandra, BS, Gheath Alatrash, DO, PhD, William K Decker, PhD, Elizabeth J Shpall, MD, M. James You, MD, PhD, Qing Ma, PhD, Jeffrey J. Molldrem, MD

Blood (2011) 118 (21): 766.

https://doi.org/10.1182/blood.V118.21.766.766

Published: 2011

Journal Articles

Membrane-Associated Proteinase 3 on Granulocytes and Myeloid Leukemia Mediates Reversible Inhibition of T Cell Proliferation

Tian-Hui Yang, MD, PhD, Karen Clise-Dwyer, PhD, Gheath Alatrash, DO, PhD, Kathryn Ruisaard, MS, Shoudan Liang, PhD, Jeffrey J. Molldrem, MD

Blood (2011) 118 (21): 1916.

https://doi.org/10.1182/blood.V118.21.1916.1916

Published: 2011

Journal Articles

A Novel HLA-A2 Restricted Peptide Derived From Cathepsin G Is An Effective Immunotherapeutic Target for Myeloid Leukemia

Mao Zhang, MPH, Pariya Sukhumalchandra, BS, Atim A. Enyenihi, PhD, Lisa S St. John, PhD, Sally A. Hunsucker, PhD, Kathryn Ruisaard, MS, Zein Al Atrache, Patricia A Ropp, PhD, Tania Rodriguez-Cruz, BS, Elizabeth Mittendorf, MD, Gregory Lizee, PhD, Karen Clise-Dwyer, PhD, Sijie Lu, PhD, Gary L. Glish, PhD, Jeffrey J. Molldrem, MD, Paul M Armistead, MD, PhD, Gheath Alatrash, D.O., Ph.D.

Blood (2011) 118 (21): 2986.

https://doi.org/10.1182/blood.V118.21.2986.2986

Published: 2011

Journal Articles

An anti–PR1/HLA-A2 T-cell receptor–like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells

Anna Sergeeva, Gheath Alatrash, Hong He, Kathryn Ruisaard, Sijie Lu, James Wygant, Bradley W. McIntyre, Qing Ma, Dan Li, Lisa St John, Karen Clise-Dwyer, Jeffrey J. Molldrem

Blood (2011) 117 (16): 4262–4272.

https://doi.org/10.1182/blood-2010-07-299248

Published: 2011

Includes: Supplemental data

NARROW

Induced PD-1 Expression on Bone Marrow CD34+ Cells from MDS Patients Treated with 5-Azacitadine in Combination with Nivolumab and/or Ipilimumab

Identification of Myeloperoxidase As a Leukemia-Associated Antigen and Therapeutic Target for Acute Myeloid Leukemia

Inhibition of T Cell Proliferation By Granulocyte Membrane-Associated Proteinase 3 Is Reversed By Blocking the Interaction of Calreticulin with LRP on T Cells

Membrane-Associated Proteinase 3 On Granulocytes and Myeloid Leukemia Mediates Reversible Inhibition of T Cell Proliferation Associated with Altered ZAP70 and ERK Signaling

RNA-Seq Expression Profiling of AML Stem Cells Reveals Differential Expression of Lineage Differentiation Markers and Novel Splice Variants.

Multiple Myeloma Cross-Presents Neutrophil Elastase and Proteinase 3 and Becomes Susceptible to PR1-Targeting Immunotherapy

Treatment with 8F4, An Anti-PR1/HLA-A2 T Cell Receptor-Like Antibody, Reduces Established Acute Myeloid Leukemia and Eliminates Leukemia Stem Cells in Mice

Membrane-Associated Proteinase 3 on Granulocytes and Myeloid Leukemia Mediates Reversible Inhibition of T Cell Proliferation

A Novel HLA-A2 Restricted Peptide Derived From Cathepsin G Is An Effective Immunotherapeutic Target for Myeloid Leukemia

An anti–PR1/HLA-A2 T-cell receptor–like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells

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American Society of Hematology

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American Society of Hematology

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